1 results match your criteria: "Massachusetts General Hospital Division of Rheumatology Allergy and Immunology[Affiliation]"
Multiorgan involvement and circulating IgG1 predict hypocomplementaemia in IgG4-related disease.
Ann Rheum Dis
November 2024
Massachusetts General Hospital Division of Rheumatology Allergy and Immunology, Boston, Massachusetts, USA.
Objectives: Hypocomplementaemia is common in patients with IgG4-related disease (IgG4-RD). We aimed to determine the IgG4-RD features associated with hypocomplementaemia and investigate mechanisms of complement activation in this disease.
Methods: We performed a single-centre cross-sectional study of 279 patients who fulfilled the IgG4-RD classification criteria, using unadjusted and multivariable-adjusted logistic regression to identify factors associated with hypocomplementaemia.