1 results match your criteria: "Massachusetts Eye and Ear Infirmary Harvard University Boston Massachusetts USA.[Affiliation]"
Human otopathology in scleroderma.
Laryngoscope Investig Otolaryngol
December 2023
Department of Otolaryngology-Head and Neck Surgery, Massachusetts Eye and Ear Infirmary Harvard University Boston Massachusetts USA.
Article Synopsis
- Scleroderma is a chronic autoimmune disease that can lead to fibrosis in the skin and internal organs, with recent studies indicating potential ear involvement, although this area remains under-researched.
- In a review of three scleroderma cases from a temporal bone database, patients exhibited tinnitus and varying degrees of sensorineural hearing loss, alongside significant histological changes in their ear structures.
- The study found notable changes such as diminished joint spaces, demineralized ossicles, vascular issues, and a reduction in spiral ganglion neurons, suggesting that these factors contribute to hearing and balance problems in scleroderma patients.