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922 results match your criteria: "MassGeneral Hospital[Affiliation]"
J Sci Med Sport
November 2024
World Rugby, Pty (Ltd), Ireland. Electronic address: https://twitter.com/Scienceofsport.
Objectives: To evaluate if the tackler correctly adhering, or not, to four different instructions of legal front-on one-on-one torso tackles altered the tackler and/or ball carrier peak inertial head kinematics.
Design: Controlled laboratory study.
Methods: Fifteen rugby-code players measured with three-dimensional optoelectronic motion capture performed two tackle instructions from the Australian National Rugby League coaching manual on under (Dominant National Rugby League) and over (Smother National Rugby League) the ball tackles, and two novel variants of these (under, Dominant, Torso Stick; over, Smother, Pop, Lock).
J Pediatr Gastroenterol Nutr
December 2024
Massachusetts General Hospital, Center for Integrated Diagnostics, Boston, Massachusetts, USA.
Primary sclerosing cholangitis (PSC) is a risk factor for cholangiocarcinoma. When a child is diagnosed with both PSC and inflammatory bowel disease (IBD), evidence-based information on counseling families and risk management of developing cholangiocarcinoma is limited. In this case series (PubMed/collaborators), we included patients with PSC-IBD who developed cholangiocarcinoma and contacted authors to determine an event curve specifying the time between the second diagnosis (IBD or PSC) and a diagnosis of cholangiocarcinoma.
View Article and Find Full Text PDFAm J Gastroenterol
December 2024
Department of Pediatrics, Division of Pediatric Gastroenterology and Nutrition, MassGeneral Hospital for Children, Harvard Medical School, Boston, Massachusetts, USA.
Public Health Rep
December 2024
Annenberg School for Communication, University of Pennsylvania, Philadelphia, PA, USA.
Objectives: Massachusetts signed into law An Act Modernizing Tobacco Control (hereinafter, the Act) in 2019, which restricted retail sales of flavored tobacco products, including menthol cigarettes. This study assessed differences in advertising exposure to flavored tobacco products among adolescents in Massachusetts compared with adolescents in 4 neighboring states after passage of the Act.
Methods: We collected monthly cross-sectional survey data from April 2021 through August 2022 among a convenience sample of adolescents (aged 13-17 y) in Massachusetts and 4 control states: Connecticut, New Hampshire, Rhode Island, and Vermont.
Psychopharmacology (Berl)
December 2024
Department of Pharmacology, Toxicology and Neuroscience, Louisiana State University Health Sciences Center, Shreveport, LA, 71130, USA.
Rationale: There is increasing interest in establishing psychedelic research programs at academic medical centers. However, psychedelics are intensely psychoactive, carry considerable sociopolitical baggage, and most are Schedule I drugs, creating significant potential impediments to implementation. There is little formal guidance for investigators on navigating the complex on-the-ground obstacles associated with establishing psychedelic research programs.
View Article and Find Full Text PDFArch Phys Med Rehabil
November 2024
Center for Health Outcomes and Interdisciplinary Research, Department of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts; Harvard Medical School, Department of Psychiatry, Boston, Massachusetts.
Acad Pediatr
October 2024
Department of Pediatrics (A Arauz Boudreau and JM Perrin), Harvard Medical School, Boston, Mass; Division of General Academic Pediatrics (A Arauz Boudreau and JM Perrin), MassGeneral Hospital for Children, Harvard Medical School, Boston.
Health financing for children and youth comes mainly from commercial sources (especially, a parent's employer-sponsored insurance) and public sources (especially, Medicaid and Children's Health Insurance Plan [CHIP]). These 2 sources serve populations that differ in race and ethnicity. This inherent segregation perpetuates a system of disparities in health and health care.
View Article and Find Full Text PDFInflamm Bowel Dis
December 2024
Pediatric IBD Foundation Bloomfield Hills, MI, USA.
EClinicalMedicine
September 2024
Department of Nursing, Chung Shan Medical University, Taichung, Taiwan.
J Pediatr Gastroenterol Nutr
December 2024
Center for Neurointestinal Health, MassGeneral Hospital, Boston, Massachusetts, USA.
Objectives: Little is known about the experience of adolescents and young adults (AYA) with disorders of gut-brain interaction (DGBI) who transition from pediatric to adult gastroenterology care. In this two-part study, we used quantitative and qualitative methods to: (1) assess incidence of optimal versus suboptimal transitions of care for AYA with DGBI, (2) characterize health and quality of life effects of the transition, and (3) identify barriers and facilitators for optimal transition of care.
Methods: In Part 1, we conducted a retrospective review of AYA referrals to our adult neurogastroenterology clinic who had transitioned from pediatric gastroenterology care (N = 109, 17-23 years, 72% female).
J Pediatr Gastroenterol Nutr
October 2024
Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Division of Gastroenterology, Hepatology and Nutrition, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.
Objectives: The prevalence of celiac disease (CeD) is increasing, yet it is still underdiagnosed, in part because of its heterogeneous presentation. Diagnostic criteria are evolving and management with strict adherence to a gluten-free diet is challenging for many. We aimed to characterize the clinical presentation of CeD among a large multicenter cohort of pediatric patients and to identify factors associated with gluten-free diet adherence.
View Article and Find Full Text PDFNutr Neurosci
August 2024
Department of Anatomy & Neurobiology, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA.
Objective: Prenatal protein malnutrition produces anatomical and functional changes in the developing brain that persist despite immediate postnatal nutritional rehabilitation. Brain networks of prenatally malnourished animals show diminished activation of prefrontal areas and an increased activation of hippocampal regions during an attentional task [1]. While a reduction in cell number has been documented in hippocampal subfield CA1, nothing is known about changes in neuron numbers in the prefrontal or parahippocampal cortices.
View Article and Find Full Text PDFHypertension
October 2024
Pediatric Nephrology Unit, MassGeneral Hospital for Children at MassGeneral, Boston, MA (J.I.).
Hypertension has largely been viewed as a disorder of adulthood. Historically, blood pressure (BP) was not routinely measured in children because hypertension was considered uncommon in childhood. It was not until the 1970s that it was apparent that in childhood BP levels were normally lower compared with those in adults, were related to age and growth, and that abnormal BP in children needed different definitions.
View Article and Find Full Text PDFDrug Alcohol Depend
September 2024
University of Pennsylvania, Annenberg School for Communication, Philadelphia, PA, United States; University of Pennsylvania, Leonard Davis Institute of Health Economics, Philadelphia, PA, United States; Abramson Cancer Center, Tobacco and Environmental Carcinogenesis Program, Philadelphia, PA, United States. Electronic address:
J Food Allergy
April 2022
From the Department of Pediatrics, MassGeneral Hospital for Children, Boston, Massachusetts.
Background: The prevalence of pediatric food allergies is increasing. Although pediatric residents are frontline providers for children with food allergies, little is known about pediatric residents' educational experiences and comfort with infant and toddler food allergy.
Methods: An anonymous online needs assessment survey was created and distributed to 64 residents in one residency program.
Addict Behav
October 2024
University of Pennsylvania, Annenberg School for Communication, Philadelphia, PA, United States; University of Pennsylvania, Leonard Davis Institute of Health Economics, Philadelphia, PA, United States; Abramson Cancer Center, Tobacco and Environmental Carcinogenesis Program, Philadelphia, PA, United States.
Background: In November 2019, the Massachusetts legislature passed An Act Modernizing Tobacco Control and became the first state to restrict retail sales of all flavored (including menthol) cigarettes, e-cigarettes, and other tobacco products. Our study aims to provide the retailer experience of the new law from the perspectives of multiple stakeholders, including tobacco retailers themselves, public health officials, and Massachusetts residents.
Methods: We conducted in-depth interviews with seven tobacco retailers and ten public health officials from March 2021 to April 2022.
Nicotine Tob Res
May 2024
Harvard University, TH Chan School of Public Health, Department of Social and Behavioral Sciences, Boston, MA, USA.
Introduction: The Massachusetts legislature passed An Act Modernizing Tobacco Control in November 2019 to restrict retail sales of flavored commercially manufactured tobacco products including menthol products, increase penalties for violating the law's provisions, and provide health insurance coverage for tobacco treatment.
Aims And Methods: This study explores key informants' perceptions of intended and unintended impacts of implementation of the 2019 Massachusetts statewide law through a health equity and racial justice lens. We conducted in-depth interviews with 25 key informants from three key informant groups (public health officials and advocates, clinicians, and school staff) between March 2021 and April 2022.
Clin J Sport Med
September 2024
Vanderbilt Sports Concussion Center, Department of Neurological Surgery, Vanderbilt University Medical Center, Nashville, Tennessee.
Objective: To examine whether a personal history of migraines is associated with worse acute symptom burden after sport-related concussion (SRC).
Design: Retrospective cohort study.
Setting: National Collegiate Athletic Association Division III collegiate programs.
Pediatr Res
May 2024
Department of Pediatrics, MassGeneral Hospital for Children, Harvard Medical School, Boston, MA, USA.
Nicotine Tob Res
August 2024
Annenberg School for Communication, University of Pennsylvania, Philadelphia, PA, USA.
Introduction: Current measures of vaping behaviors in the U.S. do not distinguish what substances participants are vaping and to what extent they are dual-vaping nicotine and cannabis.
View Article and Find Full Text PDFObstet Gynecol
May 2024
Gillings School of Global Public Health, the Department of Obstetrics & Gynecology, and the School of Social Work, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; MassGeneral Hospital for Children, Harvard Medical School, Boston, Massachusetts; and Friends Research Institute, Baltimore, Maryland.
Child protection systems often intervene after substance-exposed births but are not designed to address the postpartum needs of the delivering parent. In this retrospective cohort study, we aimed to estimate the association between early child protection system removal and high-risk subsequent birth trajectories among a cohort of mothers with substance-exposed births in California. Of 6,893 births in 2015 with documented prenatal drug and alcohol exposure, 20.
View Article and Find Full Text PDFBrain Inj
May 2024
Department of Physical Medicine and Rehabilitation, Spaulding Rehabilitation Hospital, Schoen Adams Research Institute at Spaulding Rehabilitation, Massachusetts General Hospital, Brigham and Women's Hospital, and Harvard Medical School, Boston, Massachusetts, USA.
Primary Objective: We evaluated whether photobiomodulation with red/near infrared light applied transcranially via light emitting diodes (LED) was associated with reduced symptoms and improved cognitive functioning in patients with chronic symptoms following mild traumatic brain injury.
Research Design: Participants (3 men, 6 women; 22-61 years-old) underwent a 6-week intervention involving 18 40-minute transcranial LED treatment sessions.
Methods And Procedures: Reliable change indices were calculated for 10 neuropsychological test scores and 3 self-report questionnaires of subjective cognition, post-concussion symptoms, and depression at baseline and following treatment.
Front Hum Neurosci
January 2024
LION Lab, Sainte-Justine University Hospital Research Center, University of Montreal, Montreal, QC, Canada.
Introduction: Early childhood malnutrition affects 200+ million children under 5 years of age worldwide and is associated with persistent cognitive, behavioral and psychiatric impairments in adulthood. However, very few studies have investigated the long-term effects of childhood protein-energy malnutrition (PEM) on brain function using a functional hemodynamic brain imaging technique.
Objective And Methods: This study aims to investigate functional brain network alterations using near infrared spectroscopy (NIRS) in adults, aged 45-51 years, from the Barbados Nutrition Study (BNS) who suffered from a single episode of malnutrition restricted to their first year of life (n = 26) and controls (n = 29).
Gastroenterology
June 2024
Farncombe Family Digestive Health Research Institute, Department of Medicine, McMaster University, Hamilton, Ontario, Canada.
Celiac disease (CeD) is a chronic autoimmune condition driven by gluten ingestion in genetically predisposed individuals, resulting in inflammatory lesions in the proximal small intestine. Although the presence of specific HLA-linked haplotypes and gluten consumption are necessary for disease development, they alone do not account for the variable onset of CeD in susceptible individuals. This review explores the multifaceted role of non-host factors in CeD development, including dietary and microbial influences.
View Article and Find Full Text PDF