620 results match your criteria: "Maseno University.[Affiliation]"

Establishing and proving methodological rigor has long been a challenge for qualitative researchers where quantitative methods prevail, but much published literature on qualitative analysis assumes a relatively small number of researchers working in relative proximity. This is particularly true for research conducted with a grounded theory approach. Different versions of grounded theory are commonly used, but this methodology was originally developed for a single researcher collecting and analyzing data in isolation.

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Background: Blood component therapy helps in managing patients with reduced hematopoiesis, elevated peripheral destruction of cells, and generalized blood loss (bleeding). Increased prevalence of arterial and venous thrombotic disease linked to the impact of ABO blood group on plasma levels of coagulation glycoprotein is demonstrated by blood group non-O persons.

Objective: This study had a main objective of determining the association between blood group and change in coagulation factors in plasma preparation for transfusion purpose.

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Among the diseases threatening maize production in Africa are gray leaf spot (GLS) caused by and northern corn leaf blight (NCLB) caused by . The two pathogens, which have high genetic diversity, reduce the photosynthesizing ability of susceptible genotypes and, hence, reduce the grain yield. To identify population-based quantitative trait loci (QTLs) for GLS and NCLB resistance, a biparental population of 230 lines derived from the tropical maize parents CML511 and CML546 and an association mapping panel of 239 tropical and sub-tropical inbred lines were phenotyped across multi-environments in western Kenya.

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Fishing communities in many Sub-Saharan African countries are a high-risk population group disproportionately affected by the HIV epidemic. The association of migration with HIV and AIDS in sub-Saharan Africa is well documented. Frequent mobility, high consumption of alcohol, multiple sexual partners, transactional and commercial sex, poor health infrastructure and limited access to health services are reported among the main factors shaping the HIV epidemic in fishing communities.

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Article Synopsis
  • Despite improvements in health systems and sanitation, enteric infections and diarrhoea remain prevalent in children from low-income and middle-income countries, indicating a need for additional societal development strategies to combat these diseases.
  • This study focuses on understanding how household and neighborhood factors influence the transmission of various pathogens in children under 12 months old in Nairobi and Kisumu, Kenya, through a cohort study involving repeat testing of fecal samples for enteric pathogens.
  • Ethical approvals have been secured for this research, which aims to develop models for effective interventions to reduce multi-pathogen transmission between humans, animals, and the environment in urban settings.
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  • - The study investigated how human activities and seasonal changes affect the water quality and heavy metal concentrations in River Yala (RY) in the Lake Victoria basin by analyzing various physico-chemical parameters and ecological risks across different agricultural sites during both dry and wet seasons.
  • - Sample analysis revealed significant variability in parameters like electrical conductivity, turbidity, and heavy metal levels, with water and sediment data differing between pristine upstream areas and various agricultural farms, indicating a potential pollution impact from farming activities.
  • - The results showed that the wet season generally had a more pronounced effect on the levels of contaminants compared to the dry season, and specific heavy metals exhibited distinct correlations based on seasonal conditions, highlighting the importance of monitoring these factors for ecological health.
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Prevalence and predictors of intimate partner violence against men in Kisumu slums, Kenya.

Res Sq

October 2023

University of California and San Francisco's Division of HIV, Infectious Diseases and Global Medicine, University of California and Sans Francisco.

Article Synopsis
  • - The study focused on the prevalence and predictors of intimate partner violence against men in Kisumu slums, Kenya, revealing a high prevalence rate of 76.1% among surveyed males.
  • - Key findings indicated that married or cohabiting men were significantly more likely to experience physical and economic violence, while those who were divorced or had lower education levels faced heightened risks for sexual violence.
  • - The research emphasizes the need for safe spaces for men to share their experiences and highlights the influence of socio-demographic factors like age, marital status, education, and religion on the types of violence encountered.
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Little is known about the developmental trajectories of parental self-efficacy as children transition into adolescence. This study examined parental self-efficacy among mothers and fathers over 3 1/2 years representing this transition, and whether the level and developmental trajectory of parental self-efficacy varied by cultural group. Data were drawn from three waves of the Parenting Across Cultures (PAC) project, a large-scale longitudinal, cross-cultural study, and included 1178 mothers and 1041 fathers of children who averaged 9.

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The cost of beauty: Perspectives of salon workers in Kisumu City, Kenya.

PLOS Glob Public Health

November 2023

Department of Zoology, Maseno University, Kisumu, Kenya.

Despite occupational exposure to hazardous chemicals in cosmetics and personal care products (PCPs), salon workers receive minimal formal protections. Consequently, most salon workers rely on personal safeguards. However, the nature of such individual-level safeguards remains unknown.

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Background: Malnutrition is a significant problem in Africa. In Kenya, 26% of under-fives are stunted; slums are the hardest hit. Obunga slum has the highest prevalence at 40%.

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Background: The rise of insecticide resistance against malaria vectors in sub-Saharan Africa has resulted in the need to consider other methods of vector control. The potential use of biological methods, including larvivorous fish, Bacillus thuringiensis israelensis (Bti) and plant shading, is sustainable and environmentally friendly options. This study examined the survivorship of Anopheles arabiensis and Anopheles funestus larvae and habitat productivity in four permanent habitat types in Homa Bay county, western Kenya.

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Background: Kenya has a paediatric HIV burden of nearly 140,000 children, of which only 48% of those on antiretroviral therapy (ART) have achieved the desired viral suppression possibly due to vitamin D deficiency. We explored the influence of vitamin D levels on treatment outcome.

Method: We performed a cross-sectional study of 196 participants aged 3 - 14 years; among them 98 HIV infected who received treatment between 2019 - 2020 in Jaramogi Oginga Odinga Teaching and Referral Hospital, Kenya.

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Multipole expansion is a powerful technique used in many-body physics to solve dynamical problems involving correlated interactions between constituent particles. The Laplace multipole expansion series of the Coulomb potential is well established in literature. We compare its convergence with our recently developed perturbative and analytical alternative multipole expansion series of the Coulomb potential.

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Parenting that is high in rejection and low in acceptance is associated with higher levels of internalizing (INT) and externalizing (EXT) problems in children and adolescents. These symptoms develop and can increase in severity to negatively impact adolescents' social, academic, and emotional functioning. However, there are two major gaps in the extant literature: (a) nearly all prior research has focused on between-person differences in acceptance/rejection at the expense of examining intraindividual variability (IIV) across time in acceptance/rejection; and (b) no prior studies examine IIV in acceptance/rejection in diverse international samples.

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Underfunded healthcare infrastructures in low-resource settings in sub-Saharan Africa have resulted in a lack of medical devices crucial to provide healthcare for all. A representative example of this scenario is medical devices to administer paracervical blocks during gynaecological procedures. Devices needed for this procedure are usually unavailable or expensive.

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The World Health Organization recommends thermal ablation (TA) as an alternative to cryotherapy within "screen-and-treat" cervical cancer programs in low- and middle-income countries (LMICs), including among women living with HIV (WLWH). Data on TA efficacy among WLWH are limited, however. We conducted a clinical trial to evaluate efficacy of TA for treatment of biopsy-confirmed cervical intraepithelial neoplasia grades 2 and 3 (CIN2/3) among WLWH in Kenya.

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Background: Plasmodium falciparum malaria is a leading cause of pediatric morbidity and mortality in holoendemic transmission areas. Severe malarial anemia [SMA, hemoglobin (Hb) < 5.0 g/dL in children] is the most common clinical manifestation of severe malaria in such regions.

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Hesitancy to Covid-19 vaccine is a global challenge despite the compelling evidence of the value of vaccine in preventing disease and saving lives. It is suggested that context-specific strategies can enhance acceptability and decrease hesitancy to Covid-19 vaccine. Hence, the study determined uptake and determinants of Covid-19 vaccine following a sustained voluntary vaccination drive by Kenyan government.

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Background: Since mosquitoes which transmit and maintain the malaria parasite breed in the outdoor environment, there is an urgent need to manage these mosquito breeding sites. In order to elaborate more on the ecological landscape of mosquito breeding sites, the bacterial community structure and their interactions with physicochemical factors in mosquito larval habitats was characterised in Kwale County (Kenya), where malaria is endemic.

Methods: The physical characteristics and water physicochemical parameters of the habitats were determined and recorded.

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Article Synopsis
  • Motorcycle injuries represent a significant public health issue, with the study focused on analyzing motorcycle crash injuries in Kisumu City over six months in 2019.
  • A total of 1,073 patients sought care, with males comprising 73.6% of the cases and a notable case-fatality rate of 6.80%.
  • Key factors influencing mortality included age, helmet usage, and the severity of injuries, with head injuries being the most prevalent type.
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Objective: Data on long-term outcomes of preterm (PT) and low birth weight (LBW) infants in countries with high rates of neonatal mortality and childhood stunting are limited, especially from community settings. The current study sought to explore growth and neurodevelopmental outcomes of PT/LBW infants from a rural community-based setting of Kenya up to 18 months adjusted age.

Design: Cross-sectional study.

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Disproportionate impact of COVID-19 severity and mortality on hospitalized American Indian/Alaska Native patients.

PNAS Nexus

August 2023

Center for Global Health, Department of Internal Medicine, University of New Mexico Health Sciences Center, MSC10 5550, 1 University of New Mexico, Albuquerque, NM 87131-0001, USA.

Epidemiological data across the United States of America illustrate health disparities in COVID-19 infection, hospitalization, and mortality by race/ethnicity. However, limited information is available from prospective observational studies in hospitalized patients, particularly for American Indian or Alaska Native (AI/AN) populations. Here, we present risk factors associated with severe COVID-19 and mortality in patients (4/2020-12/2021, n = 475) at the University of New Mexico Hospital.

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Many sub-Saharan African countries have experienced various challenges that threaten the quality of health services offered to the population. The COVID-19 pandemic disrupted access to healthcare services in many countries as they grappled with implementing measures to curb its spread. The consequences of COVID-19 have been catastrophic for maternal and newborn health.

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Kenya introduced free maternity services (FMS) in 2013 to enable all pregnant women to give birth for free in all government public health facilities. Currently, Kenya is rolling out universal health coverage (UHC), which has been acknowledged as a priority goal for every health system and part of the 'Big Four Agenda' for sustainable national development in Kenya. FMS is one of the core services in Kenya, but since its launch, it is not clear whether the decentralized approach chosen to implement FMS is leading to UHC.

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Article Synopsis
  • The study aimed to assess survival rates and identify factors related to mortality in tuberculosis (TB) patients in Vihiga County, finding a notable mortality rate of 15% among 291 patients examined.
  • Using statistical methods like Kaplan-Meier for survival probability and Cox proportional hazard model for predictors, key risk factors included comorbidities, severe illness, HIV infection, and smoking, significantly affecting mortality rates.
  • Results indicated a higher death rate in HIV-positive patients (27%) compared to HIV-negative ones (9%), highlighting the urgent need for targeted interventions and better healthcare management for these vulnerable groups.
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