3 results match your criteria: "Maryland (NJD); New England College of Optometry[Affiliation]"
Combination Olaparib and Temozolomide in Relapsed Small-Cell Lung Cancer.
Cancer Discov
October 2019
Massachusetts General Hospital Cancer Center, Boston, Massachusetts.
Small-cell lung cancer (SCLC) is an aggressive malignancy in which inhibitors of PARP have modest single-agent activity. We performed a phase I/II trial of combination olaparib tablets and temozolomide (OT) in patients with previously treated SCLC. We established a recommended phase II dose of olaparib 200 mg orally twice daily with temozolomide 75 mg/m daily, both on days 1 to 7 of a 21-day cycle, and expanded to a total of 50 patients.
View Article and Find Full Text PDFQuality of eyeglass prescriptions from a low-cost wavefront autorefractor evaluated in rural India: results of a 708-participant field study.
BMJ Open Ophthalmol
June 2019
PlenOptika, Inc, Boston, Massachusetts, USA.
Objective: To assess the quality of eyeglass prescriptions provided by an affordable wavefront autorefractor operated by a minimally trained technician in a low-resource setting.
Methods And Analysis: 708 participants were recruited from consecutive patients registered for routine eye examinations at Aravind Eye Hospital in Madurai, India, or an affiliated rural satellite vision centre. Visual acuity (VA) and patient preference were compared between trial lenses set to two eyeglass prescriptions from (1) a novel wavefront autorefractor and (2) subjective refraction by an experienced refractionist.
Design and Clinical Evaluation of a Handheld Wavefront Autorefractor.
Optom Vis Sci
December 2015
*PhD †OD, PhD Madrid-MIT M+Visión Consortium, Massachusetts Institute of Technology, Cambridge, Massachusetts (NJD, SRD, DL, EL); Department of Biomedical Engineering, Johns Hopkins University, Baltimore, Maryland (NJD); New England College of Optometry, Boston, Massachusetts (FAV-D, FT); Instituto de Óptica "Daza de Valdés," Consejo Superior de Investigaciones Científicas, Madrid, Spain (CD, SM); and Instituto de Investigaciones Biomédicas "Alberto Sols," UAM/CSIC, Madrid, Spain (EL).
Purpose: To introduce a novel autorefractor design that is intended to be manufacturable at low cost and evaluate its performance in measuring refractive errors.
Methods: We developed a handheld, open-view autorefractor (the "QuickSee" [QS]) that uses a simplified approach to wavefront sensing that forgoes moving parts and expensive components. Adult subjects (n = 41) were recruited to undergo noncycloplegic refraction with three methods: (1) a QS prototype, (2) a Grand Seiko WR-5100K (GS) autorefractor, and (3) subjective refraction (SR).