5 results match your criteria: "Marudhar Kesari Jain College for Women[Affiliation]"
An Investigation on Optical, Larvacidal and Cytotoxicity Analysis of Sulfanilic Acid Single Crystal for Optical and Biomedical Applications.
Cell Biochem Biophys
September 2024
Department of Physics, Jamal Mohamed College (Autonomous), Trichy, 620 020, Tamilnadu, India.
Article Synopsis
- Sulfanilic acid (SFA) crystal is a versatile material used in photonics and biomedical applications, and this article discusses the growth of a high-quality SFA single crystal using the slow evaporation solution method over 75 days.
- The resulting transparent crystal, measuring 5 × 5 × 2 mm, underwent various characterizations such as Single Crystal XRD, FTIR, UV-Visible analysis, and Scanning Electron Microscopy to assess its structural and optical properties.
- Notably, this study is the first to explore the cytotoxicity and larvicidal activity of SFA crystal, testing its efficacy against cancer cells and potential anti-malarial properties using the MTT Assay.
Biogenic synthesis and characterization of silver nanoparticles (AgNPs) from aqueous extract of Lepidagathis cristata along with their antibacterial and antineoplastic activity to combat breast cancer cells (MCF-7).
Luminescence
September 2024
Department of Biochemistry, Marudhar Kesari Jain College for Women, Vaniyambadi, Tamilnadu, India.
Lepidagathis cristata (L. cristata) plant produces reducing and capping agents; this study utilized microwave-assisted biogenic synthesis to manufacture silver nanoparticles (AgNPs) using this plant. The structure, morphology, and crystallinity phases of prepared nanoparticles (NPs) were characterized by ultraviolet-visible spectroscopy (UV-viz), powder X-ray diffraction (XRD), Fourier-transform infrared (FTIR) spectroscopy, and scanning electron microscopy (SEM).
View Article and Find Full Text PDFEvaluation of xanthene-appended quinoline hybrids as potential leads against antimalarial drug targets.
Mol Divers
April 2023
Department of Chemistry, School of Advanced Sciences, Vellore Institute of Technology, Vellore, Tamil Nadu, 632014, India.
A series of fused heterocycle xanthene-appended quinoline 6a-n was successfully synthesized with regioselectivity and characterized using IR, H NMR, C NMR, and mass spectral data. Molecular docking was performed to find the binding efficacy of all these newly synthesized compounds towards thirteen antimalarial drug targets. Molecular dynamics simulation was carried out to predict the stability of the ligand-bound complex in a solvent medium.
View Article and Find Full Text PDFIdentification of marker genes in Alzheimer's disease using a machine-learning model.
Bioinformation
February 2021
Department of Biological Sciences and Engineering, Netaji Subhas Institute of Technology, Dwarka - 110078, New Delhi, India.
Alzheimer's Disease (AD) is one of the most common causes of dementia, mostly affecting the elderly population. Currently, there is no proper diagnostic tool or method available for the detection of AD. The present study used two distinct data sets of AD genes, which could be potential biomarkers in the diagnosis.
View Article and Find Full Text PDFIdentification of zebrafish fumarate hydratase active site by molecular docking and simulation studies.
J Biomol Struct Dyn
February 2022
Zebrafish Genetics Laboratory, Department of Genetic Engineering, School of Bioengineering, SRM Institute of Science and Technology, Kattankulathur, Chengalpattu, Tamil Nadu, India.
Fumarate hydratase (FH), one of the members of TCA cycle, acts as a catalyte for the synthesis of malate from fumarate. FH has been proposed to play as a tumour suppressor leading to the pathogenicity of leiomyomas, renal cell carcinoma and paraganglioma. Mutations in the active site of FH lead to alteration in the protein structure.
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