292 results match your criteria: "Marshall University Joan C Edwards School of Medicine[Affiliation]"

Prosthetic joint infection (PJI), caused by Streptococcus bovis group (SBG), is uncommon and related to colorectal cancer. We present here a case of an 84-year-old male who had a past medical history of chronic obstructive pulmonary disease (COPD), congestive heart failure, pulmonary arterial hypertension, iron deficiency anemia, chronic kidney disease, diabetes mellitus, gout, hypertension, bilateral knee replacement with left knee pain and swelling. We initially suspected gout and treated him with prednisolone, but it did not relieve him.

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Whippets abuse, prevalent among recreational drug users, poses significant health risks, particularly through the inactivation of vitamin B12 by nitrous oxide (NO). This deficiency can lead to myelopathy, resulting in serious neurological complications. We present two female patients, aged 22 and 35, with a history of regular whippet use over the past three years, who exhibited clinical symptoms of myelopathy, including motor weakness, rigidity, sensory changes, and gait abnormalities.

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  • Anaplastic large cell lymphoma (ALCL) is a rare T-cell lymphoma marked by the presence of CD30 and can often be mistaken for other conditions due to its vague symptoms.
  • A 10-year-old girl initially treated for a bacterial infection was later diagnosed with ALK-negative ALCL after a biopsy revealed the disease, with additional imaging showing lung involvement and a Murphy stage II classification.
  • The case highlights the necessity of early biopsy and molecular testing when initial treatments don't work, emphasizing that prompt diagnosis and thorough examinations can significantly enhance treatment success and patient prognosis.
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Food allergy-induced pancreatitis is a rare condition that presents unique diagnostic challenges. While acute pancreatitis (AP) is typically linked to factors such as gallstones, alcohol consumption, metabolic issues, medications, and autoimmune conditions, food allergies are seldom considered a potential cause. Diagnosing food allergy-induced pancreatitis often requires a high index of suspicion and the exclusion of more common causes of pancreatitis.

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The prevalence of obstructive sleep apnea (OSA) is on the rise, driven by various factors including more sensitive diagnostic criteria, increased awareness, enhanced technology through at-home testing enabling easy and cost-effective diagnosis, and a growing incidence of comorbid conditions such as obesity. Treating symptomatic patients with OSA syndrome to enhance quality of life remains a cornerstone approach. However, there is a lack of consensus regarding treatment to improve cardiovascular disease (CVD) outcomes, particularly in light of overall negative results from several randomized controlled trials (RCT) indicating no benefit of positive airway pressure (PAP) therapy on primary and secondary CVD events.

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We present the case of a 61-year-old man who presented to his primary care provider for a routine visit and was found to have a pulsatile mass in his right neck. This case report shows the importance of a thorough physical exam during patient visits. In this case, the physical exam resulted in the diagnosis of a carotid body tumor (CBT) prior to the patient becoming symptomatic from it.

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Hepatitis B-associated glomerulonephritis (GN) has been recognized for decades. However, only a few cases of IgA nephropathy (IgAN) in a setting of rapidly progressive glomerulonephritis (RPGN) associated with chronic hepatitis B virus (HBV) have been described. Herein, we report the case of a 42-year-old Asian female with a past medical history significant for chronic HBV on entecavir, hypertension, chronic kidney disease, and newly diagnosed breast cancer, who underwent elective bilateral mastectomy and breast augmentation.

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Objective: The aim of this study is to evaluate the 100 most highly cited articles assessing posterior communicating artery aneurysms.

Methods: In May 2024, a comprehensive search was conducted in the Scopus database using the keyword "posterior communicating artery aneurysm" The top-100 most impactful articles were ranked by citation count and analyzed for relevant factors. Citations per year were calculated to minimize the risk of bias.

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Introduction Burn injuries pose a significant public health challenge globally, with Appalachia facing unique obstacles due to its rugged terrain, economic disparities, and limited access to healthcare. Understanding mortality risk factors specific to Appalachian burn patients is crucial for optimizing treatment approaches in this underserved population. Materials and methods A retrospective analysis of burn patient data from Cabell Huntington Hospital's burn intensive care unit (BICU) over 13 years was conducted.

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  • Generalized epileptic seizures typically lead to a postictal phase with symptoms like drowsiness and confusion; however, in rare cases, skin rashes can also occur.
  • A 45-year-old male developed a pinpoint rash with non-blanchable petechiae after a seizure, which was resolved after a week of seizure management.
  • This case highlights the importance of recognizing skin manifestations post-seizure to aid in diagnosis and reduce unnecessary medical tests, suggesting they may result from changes in blood flow and inflammation during seizures.
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  • * Malaria can be transmitted by mosquitos in endemic areas and, despite being rare in the U.S., can occur in returning travelers, posing severe health risks if not promptly treated.
  • * A case study of a 17-year-old South Korean traveler illustrates the importance of thorough clinical assessment, revealing malaria despite a negative rapid test, leading to successful treatment and no lasting effects.
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COVID-19 infections have been linked with multiple neurological manifestations. One of the infrequent complications of post-COVID-19 infection is trigeminal neuropathy. Despite its infrequency, few cases of trigeminal neuropathy following COVID-19 infection have been documented in the literature.

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Strokes are a major cause of morbidity and mortality across the globe. An ischemic stroke of thalamic origin should be considered if a patient presents with a set of non-localizing symptoms such as speech issues, sensory abnormalities, chorea-like movements, ataxia and confusion that cannot be explained by a single lesion. A 78-year-old female with a past medical history of hypertension and smoking developed right-hand numbness and ataxia that progressively worsened to numbness of the entire right side of the body and right-arm hemiballismus.

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We present here the case of a woman in her 40s with a history of an adjustable gastric band placed a decade ago. After the initial procedure, she had issues with a port-site hernia, mesh placement, and explantation secondary to mesh infection. Her port was removed at the time, with the tubing left in situ with hopes of future salvage.

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We report a case of a 51-year-old female who presented to the emergency department with stroke symptoms within the time window for intravenous (IV) thrombolytic therapy. Her initial CT head imaging showed no evidence of acute changes and her CT perfusion demonstrated an area of ischemia in the left parieto-occipital region. While she had no absolute contraindications for IV tenecteplase (TNK), she was actively menstruating at the time, which could represent a relative contraindication due to increased bleeding risk from a site that would not be easily compressible.

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Pseudoachalasia is a known complication following a gastric band placement that is reversible with band removal. However, the development of a sigmoid esophagus is uncommon. Sigmoid esophagus is considered late-stage achalasia and is associated with worse outcomes with myotomy compared to earlier-stage achalasia.

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Syphilis is a sexually transmitted infection caused by the bacterium . This disease is characterized by four different stages, each presenting with a variety of manifestations or asymptomatic disease. These stages can be further broken down into early-stage syphilis, which includes primary and secondary syphilis, and late-stage syphilis, which includes tertiary syphilis.

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Introduction Heart failure (HF) poses a substantial and escalating medical and economic challenge, marked by significant morbidity and mortality. It stands as the primary cause of hospital admissions among the elderly, contributing significantly to healthcare expenditures in developed nations. Evaluating cardiac and pulmonary function remains challenging, necessitating careful interpretation to mitigate misdiagnosis and inappropriate treatment.

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Neutralizing and binding antibody responses to SARS-CoV-2 with hybrid immunity in pregnancy.

NPJ Vaccines

August 2024

Division of Maternal-Fetal Medicine, Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California San Francisco, San Francisco, CA, USA.

Hybrid immunity against SARS-CoV-2 has not been well studied in pregnancy. We conducted a comprehensive analysis of neutralizing antibodies (nAb) and binding antibodies in pregnant individuals who received mRNA vaccination, natural infection, or both. A third vaccine dose augmented nAb levels compared to the two-dose regimen or natural infection alone; this effect was more pronounced in hybrid immunity.

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Article Synopsis
  • Steroid-responsive encephalopathy associated with thyroiditis (SREAT) is a rare autoimmune disorder that causes cognitive dysfunction, often going unnoticed in medical settings.
  • A case report highlights a male patient who suffered from various neuropsychiatric symptoms linked to SREAT, stressing the importance of early diagnosis.
  • The report advocates for recognizing SREAT in patients with unexplained symptoms, showcases the role of steroids in treatment, and emphasizes the need for better diagnostic criteria and personalized treatment plans to improve patient care.
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Introduction: Catheter ablation (CA) initiates a proinflammatory process responsible for atrial fibrillation (AF) recurrence (25-40%) and pericarditis (0.8%). Due to its anti-inflammatory properties, colchicine, a microtubule inhibitor, is explored for the prevention of early AF recurrence and pericarditis after pulmonary vein isolation.

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Trauma Prevalence and Its Association With Health-Related Quality of Life in Pregnant Persons with Opioid Use Disorder.

J Addict Med

August 2024

From the Department of Psychiatry and Behavioral Neuroscience, University of Cincinnati College of Medicine, 3131 Harvey Avenue, Cincinnati, OH (TJW, FK, DL); Center for Addiction Research, University of Cincinnati College of Medicine, Cincinnati, OH (TJW, FK, DL); Depart of Psychiatry, Harvard Medical School, Boston, MA (SFG); McLean Hospital, Division of Women's Mental Health and Division of Alcohol, Drugs and Addiction, Belmont, MA (SFG); Department of Obstetrics, Gynecology, and Reproductive Sciences, University of Pittsburgh School of Medicine, Pittsburgh, PA (EEK); Magee-Womens Research Institute, University of Pittsburgh, Pittsburgh, PA (EEK); Department of Psychiatry and Behavioral Sciences and Department of Pharmacology, Vanderbilt University Medical Center, Nashville, TN (PRM); Program for Addiction Research, Clinical Care, Knowledge and Advocacy (PARCKA), Division of Epidemiology, Department of Internal Medicine, University of Utah School of Medicine, Salt Lake City, UT (AJG); Informatics, Decision-Enhancement, and Analytic Sciences (IDEAS) Center, VA Salt Lake City Health Care System, Salt Lake City, UT (AJG); Department of Family and Community Health, Marshall University Joan C. Edwards School of Medicine, Huntington, WV (THD); Department of Pediatrics, One Boston Medical Center Place, Boston Medical Center, Boston, MA (EMW); University of Pittsburgh School of Medicine, Department of Psychiatry, Western Psychiatric Hospital, University of Pittsburgh Medical, Pittsburgh, PA (AD, XX); Department of Family Medicine Oregon Health Sciences University Portland, OR (KP); Department of Population Health Sciences, Joan & Sanford I. Weill Medical College of Cornell University, New York, NY (AJ); and Departments of Behavioral Science and Psychiatry, Center on Drug and Alcohol Research University of Kentucky College of Medicine, Lexington, KY (MRL).

Objectives: Trauma screening is recommended for pregnant persons with opioid use disorder (OUD), but there is limited literature on screening results from buprenorphine treatment. This study's objectives were to 1) describe the types, and severity, of traumatic events reported and 2) evaluate the associations between trauma and health-related quality of life (HRQoL).

Methods: Baseline data from an ongoing trial were analyzed.

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Objective: This study aimed to evaluate the cost vs. benefits of the CT face imaging study in the trauma workup of those over the age of 65.

Methods: We performed a retrospective chart review of 169 trauma patients in our trauma database aged 65 years or older who underwent a CT of the head, a CT of the face, or a CT of the head and CT of the face that resulted in findings of a facial fracture from 2017-2022.

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Duodenal varices pose a significant clinical challenge due to their association with severe gastrointestinal bleeding. This condition requires attention because of its acute severity, high morbidity, and mortality rates. The presented case underscores the importance of advancing both knowledge and treatment approaches for duodenal varices.

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Article Synopsis
  • * Its causes are not fully understood but may involve genetics, environmental factors, and immune system issues; certain medications can also trigger SCLE, such as calcium channel blockers and diuretics.
  • * A case is highlighted where SCLE developed in a patient receiving intravenous immunoglobulin (IVIG) for another condition, suggesting that healthcare providers across specialties should be aware of this potential side effect.
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