5,777 results match your criteria: "Marquette University.[Affiliation]"

The ability of neurons to sense and respond to damage is crucial for maintaining homeostasis and facilitating nervous system repair. For some cell types, notably dorsal root ganglia (DRG) and retinal ganglion cells (RGCs), extensive profiling has uncovered a significant transcriptional response to axon injury, which influences survival and regenerative outcomes. In contrast, the injury responses of most supraspinal cell types, which display limited regeneration after spinal damage, remain mostly unknown.

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Impact of a Quality Cardiopulmonary Resuscitation Coach on Pediatric Intensive Care Unit Resuscitation Teams.

Am J Crit Care

January 2025

Christine A. Schindler is a critical care pediatric nurse practitioner, critical care advanced practice provider program director, Children's Wisconsin/Medical College of Wisconsin, and a clinical professor, Marquette University, Milwaukee, Wisconsin.

Background: The quality cardiopulmonary resuscitation (CPR) coach role was developed for hospital-based resuscitation teams. This supplementary team member (CPR coach) provides real-time, verbal feedback on chest compression quality to compressors during a cardiac arrest.

Objectives: To evaluate the impact of a quality CPR coach training intervention on resuscitation teams, including presence of coaches on teams and physiologic metrics of quality CPR delivery in real compression events.

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This study aims to compare Latine men and women's perceptions of hostile and benevolent sexist behaviors, while also examining the associations between these perceptions and Latine cultural values. Participants who identified as Latine (55 men, 57 women; = 32.05, = 10.

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Hydrolysis of the acetyl-CoA allosteric activator by Staphylococcus aureus pyruvate carboxylase.

Arch Biochem Biophys

December 2024

Department of Biological Sciences, Marquette University, Milwaukee, WI 53201-1881, USA. Electronic address:

Pyruvate carboxylase (PC) catalyzes the carboxylation of pyruvate to oxaloacetate which serves as an important anaplerotic reaction to replenish citric acid cycle intermediates. In most organisms, the PC-catalyzed reaction is allosterically activated by acetyl-coenzyme A. It has previously been reported that vertebrate PC can catalyze the hydrolysis of acetyl-CoA, offering a potential means for the enzyme to attenuate its allosteric activation.

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Background: Head and neck squamous cell carcinoma (HNSCC) presents significant treatment challenges, particularly in cases unrelated to human papillomavirus (HPV). The chemokine receptor CXCR4, interacting with its ligand CXCL12, plays a crucial role in tumor proliferation, metastasis, and treatment resistance. This study explores the therapeutic potential of engineered monomeric and dimerized CXCL12 variants (CXCL12 and CXCL12, respectively) in HNSCC and evaluates potential additive effects when combined with radiation therapy.

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Testing the extent to which ecological communities are structured by deterministic (niche-based) assembly processes, resulting in predictable species abundance and composition, is a fundamental goal of ecology. Here we use a 10-year dataset of 55,156 lianas comprising 86 species in an old-growth tropical forest in Panama to test whether community assembly is consistent with niche-based assembly processes. We find that species diversity and community composition was maintained because species conformed to four general requirements of coexistence theory: (1) species have negative conspecific frequency-dependent feedback that control their local population size; (2) species have a stronger negative effect on their own population than that of heterospecifics; (3) the equilibrium frequencies of species correspond to their relative abundance; and (4) species have positive invasibility.

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Background: The diagnosis of syndesmotic instability is challenging, and chronically unstable injuries can potentially lead to ankle arthritic degeneration. The objective of this cadaveric study was to utilize a 3-dimensional (3D) weight-bearing computed tomography (WBCT) distance mapping algorithm for the detection of subtle syndesmotic instability, induced by complete syndesmotic ligament sectioning and stressed by isolated axial load. We hypothesized that this algorithm would accurately detect subtle syndesmotic instability.

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Background: Multiple sclerosis (MS) encompasses various symptoms, including fatigue, pain, spasticity, motor dysfunction, postural instability, sexual and bladder dysfunction, and cognitive impairment. Despite the documented benefits of exercise for alleviating MS symptoms, adherence to physical activity guidelines often is low, resulting in sedentary lifestyles among people with MS. This qualitative study explores the experiences of individuals with MS who participated in a ballroom dance intervention.

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Introduction: This study aimed to evaluate the short-term and long-term skeletal and dental asymmetry with miniscrew-assisted rapid palatal expansion (MARPE), rapid palatal expansion (RPE), and control group using cone-beam computed tomography (CBCT) analysis.

Methods: A total of 180 CBCT scans were analyzed for 60 patients divided into 3 groups: MARPE (mean age 13.7 ± 1.

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PFAS in landfill leachate: Practical considerations for treatment and characterization.

J Hazard Mater

November 2024

Black & Veatch, 11401 Lamar Ave, Overland Park, KS 66211, United States; Department of Civil, Construction, and Environmental Engineering, Marquette University, Milwaukee, WI 53233, United States.

Per- and polyfluoroalkyl substances (PFAS) are widely used in consumer products and are particularly high in landfill leachate. The practice of sending leachate to wastewater treatment plants (WWTPs) is an issue for utilities that have biosolids land application limits based on PFAS concentrations. Moreover, landfills may face their own effluent limit guidelines for PFAS.

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The Influence of a Deep Learning Tool on the Performance of Oral and Maxillofacial Radiologists in the Detection of Apical Radiolucencies.

Dentomaxillofac Radiol

December 2024

Diplomate ABOMR, Professor, Division of Diagnostic Sciences, Director, Oral & Maxillofacial Radiology Predoctoral Program, Section of Oral and Maxillofacial Radiology, Address: 5405 Koury Oral Health Sciences Building, UNC Adams School of Dentistry, Chapel Hill, North Carolina, 27599-7450.

Title: The Influence of a Deep Learning Tool on the Performance of Oral and Maxillofacial Radiologists in the Detection of Apical Radiolucencies.

Objectives: This study aimed to assess the impact of a deep learning model on oral radiologists' ability to detect periapical radiolucencies on periapical radiographs. The secondary objective was to conduct a regression analysis to evaluate the effects of years of experience, time to diagnose, and specialty.

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Identifying measures which accurately quantify reactive balance adaptation during walking is essential to understand how emerging perturbation-based gait paradigms impact stability over the course of an intervention. These perturbation paradigms have shown promise in reducing falls for numerous clinical populations, however tracking progress in objective terms throughout an intervention remains challenging. Whole body angular momentum (H) may be particularly suited to detect subtle adaptations in the reactive balance response and is applicable within numerous perturbation environments.

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Laser-driven betatron x rays for high-throughput imaging of additively manufactured materials.

Rev Sci Instrum

December 2024

Department of Electrical and Computer Engineering, University of Alberta, Edmonton, Alberta T6G 1H9, Canada.

Betatron x rays from a laser wakefield accelerator provide a new avenue for high-resolution, high-throughput radiography of solid materials. Here, we demonstrate the optimization of betatron x rays for three-dimensional tomography of defects in additively manufactured (AM) alloys at a repetition rate of 2.5 Hz.

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Human cytomegalovirus (HCMV) is a betaherpesvirus capable of infecting numerous cell types and persisting throughout an infected individual's life. Disease usually occurs in individuals with compromised or underdeveloped immune systems. Several antivirals exist but have limitations relating to toxicity and resistance.

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Does Social Media Increase Perioperative Anxiety in Patients Undergoing Impacted Third Molar Surgery?

J Oral Maxillofac Surg

November 2024

Resident, Department of Oral and Maxillofacial Surgery, School of Dentistry, Cukurova University, Adana, Türkiye.

Background: In anticipation of third molar surgery, patients may experience increased anxiety. Patients frequently access social media platforms and view content about surgical treatments.

Purpose: The study purpose was to measure the level of perioperative anxiety of patients scheduled for third molar surgery exposed to social media and identify factors associated with patient anxiety.

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Objective: Evaluate the effect of fathers' participation in the Preemie Prep for Parents (P3) program on maternal learning and fathers' preterm birth knowledge.

Methods: Mothers with preterm birth predisposing medical condition(s) enrolled with or without the baby's father and were randomized to the P3 intervention (text-messages linking to animated videos) or control (patient education webpages). Parent Prematurity Knowledge Questionnaire assessed knowledge, including unmarried fathers' legal neonatal decision-making ability.

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This study suggests a way to utilize the existing medical ontology and natural language processing techniques to extract major medical concepts from lay vocabularies of health consumers on social media and group them based on the defined semantic types in the ontology. Diabetes-related discussions on Tumblr was used to test the efficiency of SpaCy and the Markov-Viterbi algorithm to map lay medical terms to the defined medical concepts in the UMLS. The system discussed in this paper can better analyze free texts, take care of word ambiguity and extract the lifestyle indicators from the daily life discussions of diabetic people on Tumblr.

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Efficacy of 3D-printed chitosan‑cerium oxide dressings coated with vancomycin-loaded alginate for chronic wounds management.

Carbohydr Polym

February 2025

Marquette University School of Dentistry, Milwaukee, WI 53233, USA; Institute for Engineering in Medicine, Health, & Human Performance (EnMed), Batten College of Engineering and Technology, Old Dominion University, Norfolk, VA 23529, USA.

Multifunctional wound dressings with antibacterial and antioxidant properties hold significant promise for treating chronic wounds; however, achieving a balance of these characteristics while maintaining biocompatibility is challenging. To enhance this balance, this study focuses on the design and development of 3D-printed chitosan-matrix composite scaffolds, which are incorporated with varying amounts of cerium oxide nanoparticles (0, 1, 3, 5, and 7 wt%) and subsequently coated with a vancomycin-loaded alginate layer. The structure, antibiotic drug delivery kinetics, biodegradation, swelling, biocompatibility, antibacterial, antioxidant, and cell migration behaviors of the fabricated dressings were evaluated in-vitro.

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Aim: The objective of this review is to determine age-related differences in behavioral outcomes of bimanual motor tasks in children and adolescents with cerebral palsy (CP).

Method: This review followed the 6-stage Joanna Briggs Institute methodology. The Embase, EBSCO CINAHL, and PubMed databases were searched on May 2024.

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Background: Diagnostic reasoning is a complex cognitive process that requires intuitive, heuristic processing from knowledge and experience, as well as deliberate and reflective thinking. Evidence on interventions to improve diagnostic reasoning is inconsistent, in part because different terms and models are used to guide research.

Purpose: To present a model of the factors of diagnostic reasoning in Advanced Practice Registered Nurses (APRNs), based on a review of the literature supporting the Metacognitive Diagnostic Reasoning (MDR) Model © .

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Introduction: Alzheimer's disease (AD) prevalence and severity are associated with increased age, female sex, and apolipoprotein E4 (APOE4) genotype. Although estrogen therapy (ET) effectively reduces symptoms of menopause including hot flashes and anxiety, and can reduce dementia risk, it is associated with increased risks of breast and uterine cancer due to estrogen receptor alpha (ERα)-mediated increases in cancer cell proliferation. Because ERβ activation reduces this cell proliferation, selective targeting of ERβ may provide a safer method of improving memory and reducing hot flashes in menopausal women, including those with AD.

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Article Synopsis
  • Plant communities consist of species with varying functional traits and evolutionary backgrounds, leading to the expectation that functional diversity increases with phylogenetic diversity.* -
  • Contrary to this expectation, a study of over 1.7 million vegetation plots showed that functional and phylogenetic diversity are weakly and negatively correlated, suggesting they operate independently.* -
  • Phylogenetic diversity is more pronounced in forests and reflects recent climate, while functional diversity is influenced by both past and recent climate, highlighting the need to assess both types of diversity for ecosystem studies and conservation strategies.*
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Search for an eV-Scale Sterile Neutrino Using Improved High-Energy ν_{μ} Event Reconstruction in IceCube.

Phys Rev Lett

November 2024

Department of Physics and Wisconsin IceCube Particle Astrophysics Center, University of Wisconsin-Madison, Madison, Wisconsin 53706, USA.

Article Synopsis
  • * The study introduces enhanced modeling techniques for neutrino flux and detector response, and it distinguishes between starting (inside) and throughgoing (outside) neutrino interaction events to improve energy resolution.
  • * The findings indicate a best-fit point for the 3+1 model with sin²(2θ_{24})=0.16 and Δm_{41}²=3.5 eV², supporting previous studies while showing consistency with no evidence of sterile neutrinos, as reflected
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