2 results match your criteria: "Marqués de Valdecilla University Hospital. Santander. Spain.[Affiliation]"
Clinical and genetic factors involved in Porto-sinusoidal vascular disorder after oxaliplatin exposure.
Dig Liver Dis
October 2024
Gastroenterology and Hepatology Department, Clinical and Traslational Research in Digestive Diseases, Valdecilla Research Institute (IDIVAL), Marqués de Valdecilla University Hospital. Santander. Spain.
Article Synopsis
- Oxaliplatin (OX) is linked to a condition called porto-sinusoidal vascular disorder (PSVD) in patients with colon cancer, and the study aimed to understand its natural progression and identify risk factors.
- A multicenter study compared patients with PSVD due to OX treatment to controls without PSVD, looking at various data points and genetic markers.
- The study found that an increase in spleen diameter was the strongest predictor of PSVD, and patients with low platelet counts a year after treatment faced a higher risk, suggesting they should be monitored for related complications.
Minimally invasive surgery has demonstrated many benefits in general surgery, particularly in colon and rectal procedures. On the other hand, it has some limitations that must be taken into account, especially technical drawback. Robotic surgery has incorporated many improvements to overcome this disadvantage, such as 3D visualization, articulating instruments assisting complex and precise movements.
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