382 results match your criteria: "Marine Biodiversity Institute of Korea[Affiliation]"

, a halophilic unicellular chlorophyte, produces bioactive compounds and biofuels applicable to various industries. Despite its industrial significance, comprehensive studies on the morphological, physiological, and biochemical characteristics of the genus remain challenging. In this study, we characterized an axenically isolated green alga from a salt pond in Taean, Republic of Korea, and assessed its industrially relevant traits.

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During a field survey of parasitic ciliates diversity in South Korea, a scuticociliate was found in a water sample collected during scuba diving. At first glance, the species looks similar to members of the genus Paranophrys especially P. magna but they differ mainly in the body size and the number of somatic kineties.

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Objective: The ghost crab Ocypode stimpsoni (Decapoda) is designated as a protected marine species in Korea due to its declining population. In this study, we successfully identified 17 microsatellite markers for O. stimpsoni through next-generation sequencing.

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is well known for its potential for biofuel production due to its high lipid content. Numerous omics and biochemical studies have explored the overall molecular mechanisms underlying the responses of sp. to nutrient availability, primarily focusing on lipid metabolism.

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Exploring sp. M21F004 for Biocontrol of Bacterial and Fungal Phytopathogens.

Mar Drugs

November 2024

Department of Agricultural Chemistry, Institute of Environmentally Friendly Agriculture, College of Agriculture and Life Sciences, Chonnam National University, Gwangju 61186, Republic of Korea.

This study explores the biocontrol potential of sp. M21F004, a lactic acid bacteria (LAB) isolated from marine environments, against several bacterial and fungal phytopathogens. Out of 50 marine bacterial isolates, sp.

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The complete mitochondrial genome of (Gastropoda, Nudibranchia, Dendrodorididae) from South Korea.

Mitochondrial DNA B Resour

December 2024

Department of Ecology and Conservation, Marine Biodiversity Institute of Korea, Seocheon, South Korea.

The complete mitochondrial genome sequence of (J. E. Gray, 1850) was determined using next-generation sequencing.

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Developing novel anti‑angiogenic agents with minimal toxicity is notably challenging for cancer therapeutics. The discovery and development of peptides, whether derived from natural sources or synthesized, has potential for developing anti‑angiogenic agents characterized by their ability to penetrate cancer cells, high specificity and low toxicity. The present study identified a ‑derived anticancer and anti‑angiogenesis marine‑derived peptide 06 (MP06).

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3D-printed polycaprolactone/collagen/alginate scaffold incorporating phlorotannin for bone tissue regeneration: Assessment of sub-chronic toxicity.

Int J Biol Macromol

December 2024

Research Center for Marine-Integrated Bionics Technology, Pukyong National University, Busan 48513, Republic of Korea; Marine Integrated Biomedical Technology Center, The National Key Research Institutes in Universities, Pukyong National University, Busan 48513, Republic of Korea; Major of Biomedical Engineering, Division of Smart Healthcare, College of Information Technology and Convergence and New-senior Healthcare Innovation Center (BK21 Plus), Busan 48513, Republic of Korea. Electronic address:

The development of effective scaffolds for bone regeneration is crucial given the increasing demand for innovative solutions to address bone defects and enhance healing process. In this study, a polycaprolactone/fish collagen/alginate (P/FC/A) 3D scaffold incorporating phlorotannin was developed to promote bone tissue regeneration. While the efficacy of the P/FC/A scaffold has been demonstrated through in vitro and in vivo experiments, its sub-chronic toxicity in animal models remains understudied, raising concerns regarding its safety in clinical application.

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Article Synopsis
  • Strain AQYS21, a green microalga from Korea, shows promise for bioactive compounds and biofuels.
  • The study explored its morphology, molecular traits, and optimal growth conditions, confirming its identity and unique features.
  • The strain's high omega-3 fatty acid content and favorable biodiesel properties indicate its potential as a sustainable feedstock for biofuel production.
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The abundance and variety of benthic diatoms inhabiting tidal flats is widely acknowledged, although it has received relatively less attention than other research areas. In this investigation, we provide a formal description of a benthic diatom found in the tidal mudflat of South Korea, based on morphological and molecular characteristics and the similarities and differences between , with morphologically similar species are also discussed. Morphological characteristics are described from light and electron microscopy images.

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Article Synopsis
  • * Octoprohibitin was successfully encapsulated using carboxymethyl chitosan and demonstrated a favorable release profile, with a total release of about 93.68% over 96 hours and less cytotoxicity compared to Octoprohibitin alone.
  • * The findings indicate that Octoprohibitin-CNPs have enhanced antibacterial activity and antibiofilm properties, making them more effective against bacterial challenges than without encapsulation.
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A cellular matrix derived from natural tissue functions as a highly biocompatible and versatile material for wound healing application. It provides a complex and highly organized environment with biological molecules and physical stimuli. Recently, various kinds of tissue/organ decellularized extracellular matrixes (dECMs) from bovine and porcine have been used as biomedical applications to support tissue regeneration but inherit religious restrictions and the risk of disease transmission to humans.

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Article Synopsis
  • Microbes play a vital role in biotechnology, necessitating the preservation and management of diverse microbial resources through culture collections.
  • These collections serve as repositories for various microorganisms, ensuring they are maintained and distributed for research, education, and industrial applications.
  • Collaborative networks, such as the World Federation for Culture Collections and regional groups, are essential for supporting the long-term viability of these resources, especially as microbiome research continues to grow and presents new challenges in sample management.
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  • The study analyzed the complete mitochondrial genome of a deep-sea asteroid, which is 16,253 base pairs long and includes 13 protein-coding genes, 22 transfer RNA genes, and 2 ribosomal RNA genes.
  • No rearrangements or deletions were found when comparing this genome to others in the Paxillosida group, while certain genes had unique start codons consistent with past echinoderm studies.
  • Challenges in establishing molecular relationships at lower taxonomic levels were noted due to limited data, but this research aims to enhance database accessibility and assist in future phylogenetic studies.
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Studies of innate immune system function in invertebrates have contributed significantly to our understanding of the mammalian innate immune system. However, in-depth research on innate immunity in marine invertebrates remains sparse. We generated the first de novo genome and transcriptome sequences of copepod Labidocera rotunda using Illumina paired-end data and conducted a comparative genome analysis including five crustaceans (four copepods and one branchiopod species).

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Medullins A-H, Sesquiterpenes from , and Their Cellular Signaling Mechanism in HDF Cells.

J Nat Prod

September 2024

Division of Biotechnology and Advanced Institute of Environment and Bioscience, College of Environmental and Bioresource Sciences, Jeonbuk National University, Iksan 54596, Korea.

A chemical investigation of an ethyl acetate-soluble layer in the culture broth of resulted in the isolation of eight novel sesquiterpenes conjugated Gly (), l-Val (), l-Ala (), l-Tyr (), l-Thr (), l-Ile (), l-Leu (), and l-Phe (). Elucidation of their structures was performed through comprehensive spectroscopic analysis. The absolute configuration of the sesquiterpene skeleton was ascertained using modified Mosher's methods.

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The Laptev Sea (LS) and Western East Siberian Sea (W-ESS) are paradigmatic examples of seas dominated by terrestrial organic matter, attributed to substantial Siberian River discharges and coastal erosion. The influx of terrestrial organic matter significantly alters the biochemical composition of particulate organic matter (POM) in these Arctic coastal regions, potentially reducing the nutritional quality available to higher trophic levels. This study investigated the origin and qualitative characteristics of POM in the LS and W-ESS during the late summer of 2018 by analyzing elemental ratios (C/N ratio), stable carbon isotopes (δC), and biochemical compositions (biomolecular and amino acid (AA) compositions).

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Article Synopsis
  • The study focuses on the marine red alga known for its economic importance in agar production and medicinal compounds, presenting its complete mitochondrial genome (mitogenome) for the first time.
  • The mitogenome is a circular structure with 25,909 base pairs, containing 24 protein-coding genes, 2 ribosomal RNA genes, 24 transfer RNA genes, and an open reading frame of unknown function, demonstrating highly conserved gene structures.
  • Phylogenetic analysis indicates that this alga is closely related to other species in its family, and this research will aid in future studies on the evolutionary relationships of marine red algae.
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Article Synopsis
  • - The aquaculture industry struggles with bacterial infections in fish, worsened by the overuse of traditional antibiotics, leading to antibiotic resistance.
  • - This study explored the antibacterial potential of brown seaweed extracts, specifically their combined effectiveness with traditional antibiotics like erythromycin and oxytetracycline against harmful fish bacteria.
  • - Results indicated that the ethyl acetate fraction of the seaweed extract showed strong antibacterial activity and enhanced the effectiveness of erythromycin, suggesting it's a promising natural alternative to combat antibiotic resistance in aquaculture.
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This study explores the anti-obesity effects of the ethyl acetate extract of (EC-ETAC) on 3T3-L1 preadipocytes, focusing on its impact on adipogenesis, lipolysis, and adipose browning via the HO-1/Nrf2 pathway. Western blot analysis revealed that EC-ETAC significantly inhibited adipogenic transcription factors (PPARγ, C/EBPα, SREBP-1) and lipogenesis-related proteins (FAS, LPL). Concurrently, EC-ETAC enhanced lipolytic markers (p-AMPK, p-HSL) and adipose browning-related proteins (UCP-1, PGC-1α), indicating its role in promoting lipolysis and adipose browning.

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Determining the genetic diversity and source rookeries of sea turtles collected from feeding grounds can facilitate effective conservation initiatives. To ascertain the genetic composition and source rookery, we examined a partial sequence of the mitochondrial control region (CR, 796 bp) of 40 green turtles () collected from feeding grounds around the Korean Peninsula between 2014 and 2022. We conducted genetic and mixed-stock analyses (MSA) and identified 10 CR haplotypes previously reported in Japanese populations.

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sp. nov. a zeaxanthin-producing marine bacterium isolated from coastal sediment.

Int J Syst Evol Microbiol

May 2024

National Marine Biodiversity Institute of Korea, 101-75, Jangsan-ro, Janghang-eup, Seocheon-gun Chungcheongnam-do 33662, Republic of Korea.

Article Synopsis
  • A new Gram-negative bacterium, strain YSD2104, was isolated from coastal sediment in the Yellow Sea and is characterized as aerobic, yellow-pigmented, and rod-shaped.
  • Phylogenetic analysis indicates it is closely related to three other type strains, with significant similarities in genetic sequences and a circular chromosome of 3.54 Mbp.
  • Strain YSD2104 thrives at temperatures of 20-30°C, prefers pH 7.0, and shows notable fatty acid and lipid profiles, leading to its classification as a novel species within its genus.
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Roles of Pseudomonas aeruginosa siderophores in interaction with prokaryotic and eukaryotic organisms.

Res Microbiol

September 2024

Department of Food Science and Technology, Pukyong National University, Busan 48513, Republic of Korea; Marine Integrated Biomedical Technology Center, The National Key Research Institutes in Universities, Pukyong National University, Busan, 48513, Republic of Korea; Research Center for Marine Integrated Bionics Technology, Pukyong National University, Busan 48513, Republic of Korea.

Pseudomonas aeruginosa is an opportunistic pathogen that produces two types of siderophores, pyoverdine and pyochelin, that play pivotal roles in iron scavenging from the environment and host cells. P. aeruginosa siderophores can serve as virulence factors and perform various functions.

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Three new nonenes from culture broth of marine-derived fungus Albifimbria verrucaria and their cytotoxic and anti-viral activities.

J Antibiot (Tokyo)

July 2024

Division of Biotechnology and Advanced Institute of Environment and Bioscience, College of Environmental and Bioresource Sciences, Jeonbuk National University, Gobong-ro 79, Iksan, 54596, Republic of Korea.

Article Synopsis
  • - Three new compounds called verrucanonenes A–C were discovered from a marine fungus named Albifimbria verrucaria using various chromatography techniques to purify them.
  • - The structures of these nonenes were determined through spectroscopic methods, ensuring their unique characteristics were understood.
  • - The compounds were tested for their ability to kill cancer cells, showing significant cytotoxicity against the DU145 cancer cell line and also demonstrated a protective effect against H1N1 virus in specific cell types.
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Modulating intestinal health: Impact of chitooligosaccharide molecular weight on suppressing RAGE expression and inflammatory response in methylglyoxal-induced advanced glycation end-products.

Int J Biol Macromol

June 2024

Division of Functional Food Research, Korea Food Research Institute, 245 nongsaengmyeong-ro, Iseo-myeon, Wanju-gun, Jeollabuk-do 55365, Republic of Korea; Department of Food Biotechnology, University of Science and Technology, Daejeon 34113, Republic of Korea. Electronic address:

The accumulation of methylglyoxal (MGO) produced in high-temperature processed foods and excessive production in the body contributes to intestinal barrier dysfunction. In this study, we investigated the effects of chitooligosaccharides (COSs) of different molecular weights (<1 kDa, 1-3 kDa, 3-5 kDa, 5-10 kDa, and >10 kDa) on MGO-induced intestinal barrier dysfunction. We investigated the effect of COSs on inhibiting intracellular MGO accumulation/MGO-derived AGEs production and regulating the receptor for AGE (RAGE)-mediated downstream protein expression, including proteins related to apoptosis and inflammation, intestinal barrier integrity, and paracellular permeability.

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