3 results match your criteria: "Marie Curie Science Research Center[Affiliation]"
Network-Based In Silico Analysis of New Combinations of Modern Drug Targets with Methotrexate for Response-Based Treatment of Rheumatoid Arthritis.
J Pers Med
October 2023
Marie Curie Science Research Center, Greensboro, NC 27407, USA.
Article Synopsis
- Methotrexate and other traditional medications are effective for rheumatoid arthritis but newer drugs are proving to be more effective by targeting the disease's underlying processes.
- A systematic review highlighted various biologics and inhibitors, showing non-TNF-α inhibitors are particularly useful for patients unresponsive to standard treatments, though they come with increased risks of side effects.
- Novel drugs like Mavrilimumab and Upadacitinib, along with new therapeutic targets, offer promising options for better managing symptoms in patients with difficult-to-treat rheumatoid arthritis.
A Review of Biomarkers in Delirium Superimposed on Dementia (DSD) and Their Clinical Application to Personalized Treatment and Management.
Cureus
May 2023
Genetics, Marie Curie Science Research Center, New York City, USA.
Delirium superimposed on dementia (DSD) occurs when patients with pre-existing dementia develop delirium. This complication causes patients to become impaired, posing safety concerns for both hospital staff and patients. Furthermore, there is an increased risk of worsening functional disability and death.
View Article and Find Full Text PDFAcute Intermittent Porphyria's Symptoms and Management: A Narrative Review.
Cureus
March 2023
Department of Medical Laboratory Technology, Northern Border University, Arar, SAU.
Acute intermittent porphyria (AIP) is an autosomal dominant disorder of heme biosynthesis in the liver that is caused by the accumulation of toxic heme metabolites aminolevulinic acid (ALA) and porphobilinogen (PBG) due to a deficiency in the enzyme hydroxymethylbilane synthase (HMBS). The prevalence of AIP is found to commonly affect females of reproductive age (ages 15-50) and people of Northern European descent. The clinical manifestations of AIP include acute and chronic symptoms that can be outlined into three phases: the prodromal phase, the visceral symptom phase, and the neurological phase.
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