Evaluation of an 2-Substituted (1-3)-β-D-Glucan, Produced by 2.6, in Models of Crohn's Disease.

1,3-β-glucans are extracellular polysaccharides synthesized by microorganisms and plants, with therapeutic potential. Among them, the 2-substituted-(1-3)-β-D-glucan, synthesized by some lactic acid bacteria (LAB), has a prebiotic effect on probiotic strains, an immunomodulatory effect on monocyte-derived macrophages, and potentiates the ability of the producer strain to adhere to Caco-2 cells differentiated to enterocytes. In this work, the 2-substituted-(1-3)-β-D-glucan polymers produced by GTF glycoyltransferase in the natural host 2.