79 results match your criteria: "Mannheim Cancer Center[Affiliation]"

Sarcomas are a grouping of rare cancers with a wide variety of histological types that are difficult to diagnose and treat. This leads to many varying challenges not only for sarcoma patients, but also for doctors, researchers, and caregivers. Patient advocacy groups have an important role to play in rare cancers such as sarcomas, especially in collaboration with experts and their medical societies.

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Background: Sarcomas are rare cancers of high heterogeneity. Health-Related Quality of Life (HRQoL) has been shown to be a prognostic factor for survival in other cancer entities but it is unclear whether this applies to sarcoma patients.

Patients And Methods: HRQoL was prospectively assessed in adult sarcoma patients from 2017 to 2020 in 39 German recruiting sites using the European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ-C30).

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Neglected geriatric assessment and overtreatment of older patients with pancreatic cancer - Results from a prospective phase IV clinical trial.

J Geriatr Oncol

June 2022

Department of Medicine II, University Medical Center Mannheim, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany; Mannheim Cancer Center (MCC), University Medical Center Mannheim, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany. Electronic address:

Article Synopsis
  • Older patients with metastatic pancreatic cancer may face higher toxicity from aggressive chemotherapy, and using geriatric assessments (GA) can help tailor their treatment plans.
  • A multicenter trial categorized patients into three groups (Go-Go, Slow-Go, Frail) based on GA scores to guide therapy decisions; however, recruitment issues led to early trial termination with only 32 participants.
  • The findings showed a significant mismatch between treatment assigned and patients' GA categories, which may indicate overtreatment, highlighting the need for better alignment between clinical evaluations and geriatric assessments in managing this patient population.
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SELNET clinical practice guidelines for soft tissue sarcoma and GIST.

Cancer Treat Rev

January 2022

Research Health Institute Fundacion Jimenez Diaz (IIS/FJD), 28015 Madrid, Spain; Hospital Fundación Jimenez Diaz University Hospital, 28040 Madrid, Spain; General de Villalba University Hospital, 28400 Madrid, Spain.

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