1,933 results match your criteria: "Manitoba Centre for Health Policy; and in Canada.[Affiliation]"

Morbidities and comorbidities associated with optic nerve hypoplasia and septo-optic-pituitary dysplasia.

Dev Med Child Neurol

January 2025

Department of Community Health Sciences, Max Rady College of Medicine, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada.

Aim: To quantify optic nerve hypoplasia (ONH) and septo-optic-pituitary dysplasia (SOD) morbidities and comorbidities.

Method: A retrospective population-based study with a case-control design was undertaken using administrative health data from Manitoba, Canada. Cases were 124 patients with ONH or SOD (70 males, 54 females; age range 6 months-36 years 8 months [mean 13 years, SD 7 years 2 months]) diagnosed from 1990 to 2019, matched to 620 unrelated population-based controls (350 males, 270 females; age range 0-36 years 8 months [mean 12 years 5 months, SD 7 years 2 months]) on birth year, sex, and area of residence.

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Background: Restrictive Medicaid policies regarding hepatitis C virus (HCV) treatment may exacerbate rural health care disparities for people who use drugs (PWUD). We assessed associations between Medicaid restrictions and HCV treatment among rural PWUD.

Methods: We compiled state-specific Medicaid treatment policies across 8 US rural sites in 10 states and merged these with participant survey data.

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Objective: Many individuals exposed to SARS-CoV-2 experience long-term symptoms as part of a syndrome called post-COVID condition (PCC). Research on PCC is still emerging but is urgently needed to support diagnosis, clinical treatment guidelines and health system resource allocation. In this study, we developed a method to identify PCC cases using administrative health data and report PCC prevalence and predictive factors in Manitoba, Canada.

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Background: Adults with intellectual or developmental disability (IDD) are at higher risk for incomplete cancer staging.

Aim: To compare unknown stage data between those with and without IDD.

Materials And Methods: We used the Ontario Cancer Registry linked to administrative health data between 2007 and 2019.

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Perspective: Incidence of Clinician-Diagnosed Lyme Disease in Manitoba, Canada 2009-2018.

Vector Borne Zoonotic Dis

January 2025

Infectious Diseases and Vaccine Programs Branch, Public Health Agency of Canada, Saint-Hyacinthe, Canada.

Article Synopsis
  • Lyme disease (LD) surveillance in Manitoba faces challenges, including underreporting, which affects the understanding of disease trends and distribution.
  • A retrospective analysis from 2009 to 2018 identified 1,658 clinician-diagnosed LD cases from over 1.6 million registrants, with the majority occurring during peak tick activity (May to July).
  • Annualized findings revealed a mean incidence of 10.17 cases per 100,000 people, significantly higher than the 30 cases reported by the Manitoba Health surveillance system, highlighting the extent of underreporting.
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Outcomes among patients with coronary artery bypass grafts presenting with acute coronary syndrome: impact of revascularization.

Ther Adv Cardiovasc Dis

January 2025

Section of Cardiology, Department of Internal Medicine, University of Manitoba Max Rady College of Medicine, Winnipeg, MB, Canada Y3006 - 409, Tache Avenue, St. Boniface Hospital, Winnipeg, MB R2H 2A6, Canada.

Background: Patients post-coronary artery bypass graft (CABG) can re-present with acute coronary syndrome (ACS); however, culprit lesion identification, as well as revascularization, is often challenging. Furthermore, the impact of revascularization in this patient group is relatively unknown.

Objectives: The purpose of our study was to evaluate the efficacy of percutaneous coronary intervention (PCI) in patients with previous CABG surgery presenting with ACS.

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Objective: Social and economic marginalizations have been associated with inferior health outcomes in Canada. Our objective was to describe the relationship between neighbourhood marginalization and COVID-19 outcomes among patients presenting to Canadian emergency departments (ED).

Methods: We conducted an observational study among consecutive COVID-19 patients recruited from 47 hospitals participating in the Canadian COVID-19 ED Rapid Response Network (CCEDRRN) between March 3, 2020, and July 24, 2022.

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Article Synopsis
  • Income-based disparities in hip fracture treatment and outcomes were examined across six high-income countries, revealing that lower-income individuals generally faced worse health outcomes.
  • The study indicated that low-income populations had higher incidence rates of hip fractures and worse 1-year mortality compared to their high-income counterparts, with the most pronounced difference in Israel.
  • Overall, high-income patients experienced shorter hospital stays, lower readmission rates, and quicker surgery times, highlighting the significant impact of income on healthcare quality and access for older adults with hip fractures.
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Background: Studies suggest that depression/anxiety form part of the multiple sclerosis (MS) prodrome. However, several biases have not been addressed. We re-examined this association after correcting for: (i) misclassification of individuals not seeking healthcare, (ii) differential surveillance of depression/anxiety in the health system, and (iii) misclassified person-time from using the date of the first MS-related diagnostic claim (i.

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Canada's First National Oral Health Research Strategy (2024-2030).

J Dent Res

December 2024

Faculty of Dental Medicine and Oral Health Sciences, McGill University, Montreal, Canada.

Recent years have seen significant positive changes and developments in oral health-related policy and data on oral health and oral health care in Canada. Simultaneously, on the international stage, the momentum for oral health and related research continues to build. These changes have led to an initiative to create Canada's first National Oral Health Research Strategy (NOHRS), which was recently published by the Canadian Institutes of Health Research-Institute of Musculoskeletal Health and Arthritis (Allison and Rock 2024).

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Background: This study characterized the risk of new-onset asthma among workers in Manitoba, Canada.

Methods: Accepted time loss claims from the Workers' Compensation Board of Manitoba from 2006 to 2019, containing workers' occupations and industries, were linked with administrative health data from 1996 to 2020. After restricting the cohort to the first claim per person in an occupation and applying age and coverage exclusions, the cohort comprised 142,588 person-occupation combinations.

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Introduction: The Canadian Institute of Health Information's (CIHI) Discharge Abstract Database (DAD) contains standardised administrative data on all hospitalisations in Canada, excluding Quebec.

Objectives: We aimed to validate preterm birth related perinatal and neonatal data in DAD by assessing its accuracy against the reference standard of the Canadian Neonatal Network (CNN) database.

Methods: We linked birth hospitalization data between the DAD and CNN databases for all neonates born <33 weeks gestational age (GA) admitted to the Neonatal Intensive Care Units in Winnipeg, Canada, between 2010 and 2022.

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Purpose: This Hydrocephalus Clinical Research Network (HCRN) study had two aims: (1) to compare the predictive performance of the original ETV Success Score (ETVSS) using logistic regression modeling with other newer machine learning models and (2) to assess whether inclusion of imaging variables improves prediction performance using machine learning models.

Methods: We identified children undergoing first-time ETV for hydrocephalus that were enrolled prospectively at HCRN sites between 200 and 2020. The primary outcome was ETV success 6 months after index surgery.

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Objectives: This study examined the association between care unit work environments in long-term care (LTC) homes and trends in care aides' job satisfaction and burnout (exhaustion, cynicism, reduced professional efficacy) from 2014 to early 2020.

Design: This was a retrospective longitudinal study using data from care aide surveys collected by the Translating Research in Elder Care research program over 3 periods: September 2014-May 2015 (T), May 2017-December 2017 (T), and September 2019-March 2020 (T).

Settings And Participants: The study included 631 care aides from a stratified random sample of 84 LTC homes in 3 Canadian provinces, who participated in data collection at all 3 time points.

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Zenker per-oral endoscopic myotomy (Z-POEM): The ideal first-line therapy for treatment of Zenker diverticulum.

J Thorac Cardiovasc Surg

December 2024

Section of Thoracic Surgery, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada; CancerCare Manitoba Research Institute, Winnipeg, Manitoba, Canada; Department of Physiology & Pathophysiology, University of Manitoba, Winnipeg, Manitoba, Canada; Department of Biomedical Engineering, University of Manitoba, Winnipeg, Manitoba, Canada. Electronic address:

Objective: Zenker diverticulum is a mucosal herniation at the pharyngoesophageal junction. Although open surgical myotomy is the conventional treatment, robust evidence on third-space flexible endoscopic myotomy is lacking. We assessed safety, effectiveness, and patient-reported outcomes of per-oral endoscopic myotomy (Z-POEM) in the largest reported single-center experience with this technique.

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Objective: This study examined the effects of medical fitness facility (MFF) attendance, a proxy for exercise, on the incidence of mental disorders.

Methods: This retrospective cohort study linked members at two MFFs in Winnipeg, Canada, to health administrative databases held at the Manitoba Centre for Health Policy population research data repository. Adults aged ≥ 18 years were assigned an index date at MFF membership enrollment between January 1, 2005, and December 31, 2015, and matched to controls based on propensity score weighting.

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Background: There is a large literature on the prevalence of disability in older men, but less data on the incidence of new disability.

Objectives: 1. To determine the incidence of moderate-to-severe disability in a prospective cohort study of aging men; and 2.

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Trends in Gestational Diabetes in Manitoba From 1981 to 2019: A Descriptive Study With Geospatial Mapping.

Can J Diabetes

November 2024

Children's Hospital Research Institute of Manitoba, Winnipeg, Manitoba, Canada; The Diabetes Research Envisioned and Accomplished in Manitoba (DREAM) Theme of the Children's Hospital Research Institute of Manitoba, Winnipeg, Manitoba, Canada; Faculty of Kinesiology and Recreation Management, University of Manitoba, Winnipeg, Manitoba, Canada; Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada.

Article Synopsis
  • There has been a significant increase in gestational diabetes incidence in Manitoba, rising from 1.3% to 8.6% between 1981 and 2019, particularly after 2010.
  • The most considerable increases were noted among urban residents, people over 35 years old, and those in higher socioeconomic status (SES) groups.
  • Geospatial mapping indicates that neighborhoods with higher proportions of recent immigrants also experienced a steeper rise in gestational diabetes cases, highlighting the need for more research on screening practices.
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Article Synopsis
  • The study examines the use of antiseizure medications (ASMs) among pregnant individuals in four Canadian provinces over 20 years, focusing on trends and patterns in ASM usage among those with and without epilepsy.
  • Results showed that only 0.7% of the pregnant population had epilepsy, with 1.7% exposed to ASMs; notable increases in ASM use were observed among those without epilepsy, especially in Manitoba, Saskatchewan, and Alberta.
  • The analysis also revealed shifts in ASM drug classes, with a decline in older medications like carbamazepine and a rise in newer options like lamotrigine, while usage patterns varied by province and trimester.
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Inflatable penile prosthesis (IPP) implantations are commonly performed in hospital settings which accommodate an overnight stay and are increasingly being performed as day procedures in outpatient settings with same-day discharge. This study sought to investigate the safety and feasibility of day surgery insertion of an IPP. Surgical parameters and incidence of postoperative complications including infection, hospital admission, emergency room visitation, and additional analgesia were investigated.

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Objective: Interpersonal violence (IV) in sport is challenging to define, prevent and remedy due to its subjectivity and complexity. The 2024 International Olympic Committee Consensus on Interpersonal Violence and Safeguarding aimed to synthesise evidence on IV and safeguarding in sport, introduce a new conceptual model of IV in sport and offer more accessible safeguarding guidance to all within the sports ecosystem by merging evidence with insights from Olympic athletes.

Methods: A 15-member expert panel performed a scoping review following Joanna Briggs Institute methodologies.

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Falls and hip fractures are a major health concern among older adults in long term care (LTC) with almost 50% of residents experiencing a fall annually. Hip fractures are one of the most important and frequent fall-related injuries in LTC. There is moderate to strong certainty evidence that multifactorial interventions may reduce the risk of falls and fractures; however, there is little evidence to support its implementation.

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Data-Driven Cutoff Selection for the Patient Health Questionnaire-9 Depression Screening Tool.

JAMA Netw Open

November 2024

Department of Epidemiology, Biostatistics and Occupational Health, McGill University, Montréal, Québec, Canada.

Article Synopsis
  • The study investigates how using small datasets to select an optimal cutoff score for the Patient Health Questionnaire-9 (PHQ-9) can lead to inaccurate results.
  • Researchers evaluated whether data-driven methods for cutoff selection resulted in scores that were significantly different from the true population optimal score and if these methods produced biased accuracy estimates.
  • Findings showed that many small studies frequently failed to identify the correct optimal cutoff score, particularly in smaller samples, leading to an overestimation of test sensitivity.
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Article Synopsis
  • The study investigates the HIV epidemic among gay, bisexual, and other men who have sex with men (GBMSM) in Kenya, emphasizing their disproportionate rates of infection and the need for tailored public health strategies.
  • Researchers collected dried blood spots from 2,450 participants in different counties and found that 18.5% were living with HIV, with only a small number successfully sequenced due to high rates of viral suppression.
  • Results indicated that the majority of identified HIV phylogenetic clusters involved GBMSM who sought partners online and tested less frequently than recommended, highlighting important gaps in HIV prevention and care within the community.
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