Tuning the optical properties of gold nanoparticles photoactive liquid crystalline azo ligands.

In the field of modern nanoscience, the ability to tailor the properties of nanoparticles is essential for advancing their applications. A key approach for achieving this control involves manipulating surface plasmon resonance (SPR) to modify optical properties. This study introduces a novel method for synthesizing gold nanoparticles capped with photoactive liquid crystalline azo ligands, accomplished without reducing agents.

Inter-relational dynamics of factors affecting the emergence of orphan drugs.

Orphan drugs are medications that are produced for the treatment of rare diseases. As there is less number of patients, the drug manufacturing companies are not keen in producing these drugs. Due to high costs of research and development and low profitability, companies do not want to invest in manufacturing of orphan drugs.

Subtype prevalence and treatment implication in adolescents and adults with mild-to-moderate asthma: Systematic review and meta-analysis.

Background: Inhaled corticosteroid (ICS)-containing regimens are the mainstay for treating asthma despite usually being ineffective in noneosinophilic asthma (NEA). Data on the prevalence of NEA versus eosinophilic asthma (EA) in mild-to-moderate asthma are limited.

Objective: We performed a systematic review of the prevalence of mild-to-moderate asthma in adolescents and adults using sputum inflammatory cell analysis and their responses to ICS.

Sodium chloride-induced metabolic shifts and morpho-physiological responses in (L.) Wettst. for enhanced bacoside-A production.

This study investigated the impact of NaCl concentrations (50-200 mM) on (BM) grown under natural environmental conditions. The results revealed significant enhancements ( < 0.05) in various traits under NaCl exposure.

A method to enhance privacy preservation in cloud storage through a three-layer scheme for computational intelligence in fog computing.

Recent advancements in cloud computing have heightened concerns about data control and privacy due to vulnerabilities in traditional encryption methods, which may not withstand internal attacks from cloud servers. To overcome these issues about the data privacy and control of transfer on cloud, a novel three-tier storage model incorporating fog computing method has been proposed. This framework leverages the advantages of cloud storage while enhancing data privacy.

Tough, durable and strongly bonded self-healing cartilage-mimicking noncovalently assembled hydrogel nanostructures: the interplay between experiment and theory.

High-strength, strongly bonded and self-healing materials are of great interest for several applications; however, the experimental and design of all such properties in a single material is challenging. In the present work, inspired by cartilage tissue, polyacrylamide (PAM)-based tough and durable dimer (PAM-Ag and PAM-BNOH) and trimer (PAM-Ag-BNOH) nanocomposites were synthesized by encapsulating silver (Ag) and hydroxylated hexagonal boron nitride (BNOH). Strong interfacial interaction was achieved by introducing (computational modelling and DFT approaches) noncovalent bonds in the dimer and trimer nanohybrids.

Metasurface absorber for millimeter waves: a deep learning-optimized approach for enhancing the isolation of wideband dual-port MIMO antennas.

In this communication, the concept of metasurface absorber is utilized to enhance the isolation in the dual port multiple-input multiple-output (MIMO) antenna specially designed for a wideband millimeter wave operation. The frequency of operation of the designed module is 32.5-42.

Low-dose radiation research insights in experimental animals: A gateway to therapeutic implications.

In recent years, a significant research effort has been underway to explore the effects of low-dose radiation (LDR). Animal models play a key role in various fields of research, including biomedicine, pharmaceutical, environmental, and behavioral studies. The use of animal models has been an invaluable tool in radiation research for understanding radiation biology, assessing radiation risks, and developing strategies for radiation protection and medical management.

Particle surface engineering at the nano-micro scale interfaces of metal-nonmetal bonded polymeric coatings: experimental and evaluations.

Polyvinyl alcohol (PVA) is a well-known and cost-effective synthetic polymer that offers a variety of applications, including medical, food, aerospace, automotive, and material industries, for the construction of structures. However, the weak adhesion, low wear resistance, and mechanical properties of PVA usually limit their functionality and durability. Herein, the strength and bonding of the polymeric matrix were enhanced by metallization and reinforcement of carbonaceous allotropes.

Adaptive congestion control in IoT networks: Leveraging one-way delay for enhanced performance.

With the exploding number of IoT devices generating vast data volumes, there is a growing risk of significant performance degradation without efficient congestion management. To tackle this challenge, efficient regulation and supervision are essential for managing congestion in IoT networks. This research work introduces a One-Way-Delay (OWD)-based congestion control (CC) method that estimates data transmission delays of the communication path and adjusts network traffic accordingly.

Bariatric and endo-bariatric interventions for diabetes: What is the current evidence?

Bariatric interventions have shown the best therapeutic benefits in individuals with obesity. They can be classified into surgical procedures (bariatric/metabolic surgery) and endoscopic procedures. Common surgical procedures include sleeve gastrectomy, Roux-en-Y gastric bypass, bilio-pancreatic diversion with or without duodenal switch and Stomach Intestinal Pylorus Sparing Surgery.

Ethnic foods of Northeast India: insight into the light of food safety.

Background: Traditional and fermented foods are widely consumed by the ethnic population of Northeast India. These foods are not only very nutritious, easily available, and reasonably priced, but also boost immunity and protect from various seasonal infections and have been reported through several investigations. However, pathogens transmitted by these foods have never been reported.

Liposomal topical drug administration surpasses alternative methods in glaucoma therapeutics: a novel paradigm for enhanced treatment.

Objectives: Glaucoma is a leading cause of permanent blindness. Despite therapeutic advancements, glaucoma management remains challenging due to limitations of conventional drug delivery, primarily topical eye drops, resulting in suboptimal outcomes and a global surge in cases. To address these issues, liposomal drug delivery has emerged as a promising approach.

Biomaterials for bone tissue engineering: achievements to date and future directions.

Advancement in medicine and technology has resulted into prevention of countless deaths and increased life span. However, it is important to note that, the modern lifestyle has altered the food habits, witnessed increased life-style stresses and road accidents leading to several health complications and one of the primary victims is the bone health. More often than ever, healthcare professionals encounter cases of massive bone fracture, bone loss and generation of critical sized bone defects.

Expert consensus on antimicrobial resistance research priorities to focus development and implementation of antibacterial vaccines and monoclonal antibodies.

To reduce antimicrobial resistance (AMR), pathogen-specific AMR burden data are crucial to guide target selection for research and development of vaccines and monoclonal antibodies (mAbs). We identified knowledge gaps through previously conducted systematic reviews, which informed a Delphi expert consultation on future AMR research priorities and harmonisation strategies to support data-driven decision-making. Consensus (≥80% agreement) on importance and feasibility of research topics was achieved in two rounds, involving 24 of 39 and 19 of 24 invited experts, respectively.

Modification of cellulose with TiO nanoparticles: Potential solar driven photocatalyst and adsorbent.

Unlabelled: modification of cellulose fibers with titania nanoparticles (TiO NPs) (TiO NPs-cellulose) was carried out via the sol-gel process using titania sol and fibers of cellulose. Cellulose fibers were extracted from wheat straw, an agricultural waste material, whereas titania sol was prepared from titanium(IV) acetoximate, [Ti{ONC(CH)}]. The synthesized TiO NPs-cellulose composite was characterized by FT-IR, SEM-EDX, and XRD analyses.

A dataset revolutionizing Indian bay leaf analysis.

Indian bay leaf is a crucial spice in Indian cuisine. However, its quality and authenticity are often compromised. To address this, we introduce The Digital Indian Bay leaf dataset, a comprehensive collection of high-resolution 5696 images capturing diverse bay leaf samples under controlled conditions.

In silico studies on nicotinamide analogs as competitive inhibitors of nicotinamidase in methicillin-resistant Staphylococcus aureus.

Nicotinamidase/PncA is a member of the hydrolase enzyme family, catalyzing the de-amidation of nicotinamide (NM) to nicotinic acid (NA) via salvage pathway. Products are fed into Preiss-Handler pathway for NAD biosynthesis which is an important enzyme cofactor and crucial for redox balance in microorganisms. Pathogens like methicillin-resistant Staphylococcus aureus (MRSA) are NAD auxotroph and rely on their host environment for NAD precursors to synthesize NAD.

Development of rare earth element-based hybrid aluminium composites using stir casting process.

Aerospace and marine industries are constantly in search of materials that can provide good strength and durability while also being lightweight. Aluminium composites with adequate reinforcements have been proven to be effective in achieving incredible mechanical properties while also maintaining a good strength to weight ratio. Numerous studies have been done to study the various possibilities of matrix reinforcement combinations in aluminium composites.

Association between medication adherence and blood pressure control and factors associated with antihypertensive medication adherence in the Melaka Tengah District: A cross-sectional survey.

Introduction: The burden of cardiovascular disease and early morbidity and mortality is exacerbated by hypertension. According to the 2019 National Health and Morbidity Survey, 30% of adults in Malaysia aged over 18 years had hypertension. Our study aimed to investigate the association between medication adherence and blood pressure control and the factors associated with antihypertensive medication adherence.

Antioxidant and anticancer activities of hesperetin and its novel formulations in KB cells.

This study aimed to formulate the hesperetin nanostructured lipid carriers (NLCs) containing oro-mucosal gel for its activity assessment on the KB cell line. NLCs were prepared with glyceryl monostearate, oleic acid, and lecithin using a modified constant-temperature emulsification technique. The particle size analysis, in vitro drug release studies, etc.

A prospective cohort study comparing efficacy of 1 dose of quadrivalent human papillomavirus vaccine to 2 and 3 doses at an average follow up of 12 years postvaccination.

Background: While recommending a human papillomavirus (HPV) single-dose vaccination schedule in 2022, the World Health Organization highlighted the need for long-term follow-up studies to monitor waning of protection. We report on vaccine efficacy against HPV infections in 1-, 2-, and 3-dose schedules and protection against cervical precancers at a median follow-up of 12 years postvaccination.

Methods: This randomized multicenter study in India was originally designed to vaccinate unmarried girls aged 10-18 years with either 2 or 3 doses of quadrivalent HPV vaccine.

A Deep Cryptographic Framework for Securing the Healthcare Network from Penetration.

Ensuring the security of picture data on a network presents considerable difficulties because of the requirement for conventional embedding systems, which ultimately leads to subpar performance. It poses a risk of unauthorized data acquisition and misuse. Moreover, the previous image security-based techniques faced several challenges, including high execution times.