Versatile applications of cobalt and copper complexes of biopolymeric Schiff base ligands derived from chitosan.

In the present study, biopolymeric Schiff base (SB) ligands were synthesized from chitosan and isatin. Consequently, their earth abundant transition metal complexes of cobalt and copper were synthesized. All compounds were extensively characterized using FTIR and UV spectroscopy, thermo-gravimetric (TG) analysis, X-ray powder diffraction (XRD) and FESEM (field emission scanning electron microscopy).

Recent advances in microwave-assisted synthesis of triazoles and their derivatives: a green approach toward sustainable development methods.

Triazole, a nitrogen-containing five-membered heterocycle with two isomeric forms, 1,2,3-triazole and 1,2,4-triazole, has proven to be a valuable component in the pharmaceutical domain. Owing to its widespread utility in drug development, pharmaceutical and medicinal chemistry, several synthetic methods have been explored, such as different catalytic systems, solvents, and heating methodologies in recent years. However, some methods were associated with several limitations, such as harsh reaction conditions, high temperatures, low atom economy, and long reaction times.

Translation of oral health research priorities into research topics in an equity-based priority setting exercise.

Background: In the context of research priority-setting, participants express their research priorities and ideas in various forms, ranging from narratives to explicit topics or questions. However, the transition from these expressions to well-structured research topics or questions is not always straightforward. Challenges intensify when research priorities pertain to interventions or diagnostic accuracy, requiring the conversion of narratives into the Participant, Intervention, Comparator, Outcome (PICO) format.

Material and technique fundamentals of nano-hydroxyapatite coatings towards biofunctionalization: a review.

Hydroxyapatite (HAP) nano-coatings on titanium alloys (for example, Ti6Al4V) have been used for prosthetic orthopedic implants in recent decades due to their osseointegration, bioactivity, and biocompatibility. HAP is brittle with low mechanical strength and poor adhesion on metallic surfaces, which limits its durability and bioactivity. Surface modification techniques have alleviated the imperfection of biomaterials by coating the substrate.

Evening Primrose Oil for Menopause Hot Flashes: Systematic Review and Meta-Analysis.

Hormone replacement therapy (HRT) used to treat hot flashes has side effects, such as an increased risk of coronary heart disease and breast cancer. There are ongoing controversies regarding the risk of ovarian cancer associated with HRT. HRT is best avoided in conditions such as liver or gallbladder disease and gastrointestinal disorders.

Advanced microgrid optimization using price-elastic demand response and greedy rat swarm optimization for economic and environmental efficiency.

In this paper, a comprehensive energy management framework for microgrids that incorporates price-based demand response programs (DRPs) and leverages an advanced optimization method-Greedy Rat Swarm Optimizer (GRSO) is proposed. The primary objective is to minimize the generation cost and environmental impact of microgrid systems by effectively scheduling distributed energy resources (DERs), including renewable energy sources (RES) such as solar and wind, alongside fossil-fuel-based generators. Four distinct demand response models-exponential, hyperbolic, logarithmic, and critical peak pricing (CPP)-are developed, each reflecting a different price elasticity of demand.

Advanced environmental remediation using enhanced performance of hollow ZnO@SnInS core-shell nanorod arrays for hazardous ion and organic pollutant removal.

Herein, novel hollow ZnO and ZnO@SnInS core-shell nanorods (NRs) with controlled shell thickness were developed via a facile synthesis approach for the efficient photocatalytic remediation of organic as well inorganic water pollutants. The introduction of SnInS shell layer coating over ZnO enhances visible light absorption, efficient exciton-mediated direct charge transfer, and reduces the band gap of ZnO@SnInS core-shell nanorods. The ZnO@SnInS core-shell nanorods show efficient solar-light driven catalytic efficiency for the disintegration of industrial dye (orange G), degradation of tetracycline, and reduction of hazardous Cr (VI) ions in aquatic systems.

Transfusion medicine hackathon: Nurturing the innovative ideas to revolutionize voluntary blood donation.

Background And Objective: Blood transfusion is an essential component of health care. However, several issues can hamper the promotion and sustainability of voluntary blood donation programs. This article is about a hackathon in the field of transfusion medicine that was designed to stimulate original ideas to promote voluntary blood donation.

Polymeric Nanoparticles Revolutionizing Brain Cancer Therapy: A Comprehensive Review of Strategies and Advances.

Brain cancer continues to be one of the most formidable malignancies to manage, mainly attributable to the presence of the blood-brain barrier (BBB) limiting the permeability of drugs and the diverse characteristics of brain tumors complicating treatment. The management of brain tumors has been hampered by many different factors, including the impermeability of the BBB, which restricts the delivery of chemotherapeutic agents to the tumor site, as well as intertumoral heterogeneity and the influence of brain tumor stem cells. In addition, small molecular weight drugs cannot specifically accumulate in malignant cells and have a limited circulation half-life.

Should Oral examination be Reimagined in the Era of AI?

As artificial intelligence (AI) continues to reshape education, concerns about the authenticity of student work have escalated, particularly in relation to written assignments influenced by AI-powered tools. This paper explores the role of the oral examination as a valuable method for assessing true student understanding and considers its potential for broader use across various educational levels. We propose that oral exams could be effectively integrated into undergraduate courses, providing a means to verify student comprehension in an era of AI-generated content.

Investigations on segmentation-based fractal texture for texture classification in the presence of Gaussian noise.

Texture is a significant component used for several applications in content-based image retrieval. Any texture classification method aims to map an anonymously textured input image to one of the existing texture classes. Extensive ranges of methods for labeling image texture were proposed earlier.

Synergistic inhibition of HIV-1 by Nelfinavir and Epigallocatechin Gallate: A novel nanoemulsion-based therapeutic approach.

The integration of nanotechnology into antiretroviral drug delivery systems presents a promising avenue to address challenges posed by long-term antiretroviral therapies (ARTs), including poor bioavailability, drug-induced toxicity, and resistance. These limitations impact the therapeutic effectiveness and quality of life for individuals living with HIV. Nanodrug delivery systems, particularly nanoemulsions, have demonstrated potential in improving drug solubility, enhancing bioavailability, and minimizing systemic toxicity.

Molecular Mechanisms of Vitamin E in Ocular Neurodegenerative Disorders: An Update on the Emerging Evidence and Therapeutic Implications.

Vitamin E is renowned for its potent antioxidant properties, crucial for shielding cells against oxidative stress and damage. Deficiency in this vitamin can lead to various health issues, including neurodegenerative diseases, due to its pivotal role in preserving cell membrane integrity and combating cellular oxidative damage. While its importance for overall health, including neurodegeneration, is acknowledged, the specific correlation between vitamin E deficiency and distinct ocular neurodegenerative disorders need to be further explored.

Diverse phenotype of Ménière's disease associated with family history, thyroid disorder, migraine and associated disorders.

Objective: To better understand the clinical phenotype of Ménière's disease (MD), we examined family history, thyroid disorder, migraine, and associated disorders in complaints of people living with MD.

Method: We designed the study as a retrospective and examined data gathered from 912 participants with MD. Their data were originally collected by the Finnish Ménière Federation (FMF).

Enhanced adsorption and photocatalytic degradation of tetracycline antibiotics through novel I-Bi/BiWO@MWCNTs heterostructure composite photocatalyst.

Bismuth-based photocatalysts proved to have remarkable photoactivity for antibiotic degradation from water. However, the two significant challenges of bismuth-based photocatalysts are the fast charge recombination rate and higher energy band gap. This study successfully synthesised a novel I-Bi/BiWO/MWCNTs (C-WBI) heterostructure composite photocatalysts with shorter energy band-gap and higher charge production capability through interfacial amidation linkage.

An omics-based tumor microenvironment approach and its prospects.

Multi-omics approaches are revolutionizing cancer research and treatment by integrating single-modality omics methods, such as the transcriptome, genome, epigenome, epi-transcriptome, proteome, metabolome, and developing omics (single-cell omics). These technologies enable a deeper understanding of cancer and provide personalized treatment strategies. However, challenges such as standardization and appropriate methods for funneling complex information into clinical consequences remain.

P300 Event-Related Potential: A Surrogate Marker of Cognitive Dysfunction in Parkinson's Disease Patients with Psychosis.

Background And Objectives: Psychosis is one of the major neuropsychiatric non-motor symptoms of Parkinson's disease (PD). Prolonged latency and decreased amplitude of the P300 event-related potential (ERP) is a potential neurophysiologic biomarker of deeper neurocognitive deficits in PD. We aimed to characterize electroencephalogram (EEG)/ERP parameters in PD patients with and without psychosis (PDP and PDNP, respectively), and to determine if such measures could act as endophenotypes for PD-associated psychosis (PDP).

Dynamic Palpation for Diagnosing Clinically Covert Scaphoid Fractures.

The scaphoid is the most fractured carpal bone. In the initial workup, various clinical examinations are performed. However, the diagnosis can be confounding in the setting of clinically covert fracture cases.

Importance of interprofessional collaboration in teaching diabetic foot self-management: Perceptions of health care professionals.

Background: Diabetes and associated diabetic foot ulcers require coordinated management, including several health care professional (HCPs). Therefore, an interprofessional (IP) team-based approach is essential for effectively managing and educating the population on diabetic foot self-management strategies. However, the perceptions of the HCPs related to the importance of IP teamwork in diabetic foot care and their readiness to work in an IP team are less explored.

Assessing the concentration, distribution and characteristics of suspended microplastics in the Malaysian indoor environment.

This study examines the concentration, distribution, and characteristics of suspended microplastics (MPs) across various indoor environments in Malaysia, including offices, classrooms, landed homes, and apartments. Over a six-week period, MPs were collected using a vacuum pump and analyzed through gravimetric analysis, stereomicroscopy, and Raman spectroscopy. The results revealed significant variability in MPs concentrations among different locations, with fibers identified as the predominant morphological type.

Assessment of the effect of multi-walled carbon nanotubes (-OH functionalized) on growth characteristics and biochemical profile of Brassica juncea (L.) Czern. & Coss.

This study investigated the effect of various levels of OH-MWCNTs mediated seed priming on germination, growth, and biochemical responses of Indian mustard (Brassica juncea (L.) Czern. & Coss.

A finite source retrial queueing inventory system with stock dependent arrival and heterogeneous servers.

This article discusses a finite-source stock-dependent stochastic inventory system with multiple servers and a retrial facility. The system can store a maximum of S items, and the lifetime of each item is exponentially distributed. The primary customer arrives at the waiting hall from the finite source and receives service from multi-servers.

Dental management of people with congenital hemophilia: An integrative review of case reports and case series from a global scenario.

Objective: To analyze the various dental management strategies adopted to manage patients with hemophilia in a dental clinical setup.

Methods: An electronic database search was carried out using MEDLINE by PubMed, Scopus, Google Scholar, Web of Science, and EMBASE databases from January 2000 to August 2023 for case reports and case series published in English language. Case reports addressing the dental treatments for people with hemophilia A/hemophilia B were included.

A rare complication of intracardiac double knotting of temporary pacemaker lead during bedside insertion: a case report.

Background: Temporary pacemaker lead implantation is a common low-risk procedure, but can occasionally get complicated by infections, arrhythmias, thromboembolic events, and perforation of the vessel or the heart. However, intracardiac knotting of the temporary pacemaker lead has been rarely reported. This could lead to vascular or valvular injury, pneumothorax, symptomatic loss of pacing or haemodynamic compromise, and difficult lead removal.

Tuning the optical properties of gold nanoparticles photoactive liquid crystalline azo ligands.

In the field of modern nanoscience, the ability to tailor the properties of nanoparticles is essential for advancing their applications. A key approach for achieving this control involves manipulating surface plasmon resonance (SPR) to modify optical properties. This study introduces a novel method for synthesizing gold nanoparticles capped with photoactive liquid crystalline azo ligands, accomplished without reducing agents.