3 results match your criteria: "Manipal University Manipal 576 104[Affiliation]"

Comparative Efficacy and Safety of Caffeine and Aminophylline for Apnea of Prematurity in Preterm (≤34 weeks) Neonates: A Randomized Controlled Trial.

Indian Pediatr

April 2017

Departments of Pediatrics and *Community Medicine, Women and Child block, Kasturba Hospital, Manipal. Correspondence to: Dr Leslie Edward Simon Lewis, Professor and Unit Head, Neonatal Intensive Care Unit, Department of Pediatrics, Kasturba Hospital, Manipal University Manipal 576 104, India.

Article Synopsis
  • - The study aimed to compare the effectiveness and safety of caffeine versus aminophylline in treating apnea of prematurity in preterm neonates at a hospital in Southern India.
  • - A total of 240 infants were involved in a randomized controlled trial, with one group receiving caffeine and the other aminophylline, evaluating their effects on apnea spells and associated health issues over a treatment period.
  • - Results showed that aminophylline led to fewer apnea episodes in the first week, but both treatments had similar outcomes regarding apnea rates and hospital stays; however, caffeine was linked to a lower risk of tachycardia in treated infants.
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Objective: To compare the clinical efficacy of two different dosing regimens of vaginal misoprostol for labour induction.

Material And Methods: This is an open label randomised controlled trial of 100 eligible women with obstetrical or medical indications for labour induction at a secondary level care hospital on the west coast of India. Women were randomised to receive either a single 50 μg dose or multiple 25 μg doses (maximum of three doses) of misoprostol in the posterior vaginal fornix.

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