A rare complication of intracardiac double knotting of temporary pacemaker lead during bedside insertion: a case report.

Background: Temporary pacemaker lead implantation is a common low-risk procedure, but can occasionally get complicated by infections, arrhythmias, thromboembolic events, and perforation of the vessel or the heart. However, intracardiac knotting of the temporary pacemaker lead has been rarely reported. This could lead to vascular or valvular injury, pneumothorax, symptomatic loss of pacing or haemodynamic compromise, and difficult lead removal.

Docking and molecular biology studies of -anisidine-appended 1-hydroxy-2-acetonapthanone Schiff base lanthanum(iii) complexes.

A new series of lanthanum(iii) complexes was synthesized using a -anisidine-appended 1-hydroxy-2-acetonapthanone (3) Schiff base and characterized spectroscopic methods. The ligand was synthesized sonication and the crystalline product was characterized using X-ray crystallography. The genotoxicity of the compound was assessed primarily by the bacterial reverse mutation (Ames) test and the mammalian chromosome aberration test; in both cases, the samarium complex 5 was found to be non-mutagenic.

Repeated social stress leads to contrasting patterns of structural plasticity in the amygdala and hippocampus.

Previous studies have demonstrated that repeated immobilization and restraint stress cause contrasting patterns of dendritic reorganization as well as alterations in spine density in amygdalar and hippocampal neurons. Whether social and ethologically relevant stressors can induce similar patterns of morphological plasticity remains largely unexplored. Hence, we assessed the effects of repeated social defeat stress on neuronal morphology in basolateral amygdala (BLA), hippocampal CA1 and infralimbic medial prefrontal cortex (mPFC).

Detection of genital chlamydial and gonococcal infection using urine samples: A community-based study from India.

Sexually transmitted infections (STI) have a major impact on the reproductive health of women. Among the different etiological agents of STIs, Chlamydia trachomatis and Neisseria gonorrhoeae are the main bacterial pathogens that cause sexually transmitted infections in women. The aim of the study was to estimate the prevalence of genital chlamydial and gonococcal infection among women in the age group of 18-65 years from a community-based setting.

Assessment of cost of illness for diabetic patients in South Indian tertiary care hospital.

Background: The impact of diabetes on health-care expenditures has been increasingly recognized. To formulate an effective health planning and resource allocation, it is important to determine economic burden.

Objective: The objective of this study is to assess the cost of illness (COI) for diabetic inpatients with or without complications.

Evaluation of Two Thiazolidin-4-one Derivatives in High Sucrose Diet Fed Pre-diabetic Mice and Their Modulatory Effect on AMPK, Akt and p38 MAP Kinase in L6 Cells.

We had previously demonstrated the anti-diabetic potential and pancreatic protection of two thiazolidin-4-one derivatives containing nicotinamide moiety (NAT-1 and NAT-2) in STZ-induced diabetic mice. However, due to the limitations of the STZ model, we decided to undertake a detailed evaluation of anti-diabetic potential of the molecules on a high sucrose diet (HSD) fed diabetic mouse model. Further, mechanistic studies on the phosphorylation of AMPK, Akt and p38 MAP kinase in L6 myotubes and anti-inflammatory studies in RAW264.

Ecological niche modeling for conservation planning of an endemic snail in the verge of becoming a pest in cardamom plantations in the Western Ghats biodiversity hotspot.

Conservation managers and policy makers are often confronted with a challenging dilemma of devising suitable strategies to maintain agricultural productivity while conserving endemic species that at the early stages of becoming pests of agricultural crops. Identification of environmental factors conducive to species range expansion for forecasting species distribution patterns will play a central role in devising management strategies to minimize the conflict between the agricultural productivity and biodiversity conservation. Here, we present results of a study that predicts the distribution of , a snail endemic to the Western Ghats biodiversity hotspot, which is becoming a pest in cardamom () plantations.

Plant-derived SAC domain of PAR-4 (Prostate Apoptosis Response 4) exhibits growth inhibitory effects in prostate cancer cells.

The gene Par-4 (Prostate Apoptosis Response 4) was originally identified in prostate cancer cells undergoing apoptosis and its product Par-4 showed cancer specific pro-apoptotic activity. Particularly, the SAC domain of Par-4 (SAC-Par-4) selectively kills cancer cells leaving normal cells unaffected. The therapeutic significance of bioactive SAC-Par-4 is enormous in cancer biology; however, its large scale production is still a matter of concern.

Postoperative Pancreatic Fistula: A Surgeon's Nightmare! An Insight with a Detailed Literature Review.

Context: Postoperative fistula formation is an important complication following pancreatic resections.

Objective: A large volume of literature without uniform conclusions is available regarding various controversies about postoperative pancreatic fistulae. The term postoperative pancreatic fistula includes fistula resulting from any surgery involving pancreas, most commonly pancreaticoduodenectomy and distal pancreatectomy.

Arterial glomerulus at the hilum of the right kidney and the abnormal course of the right testicular artery: a case report.

Variations in the origin of arteries in the abdomen are very common. With the invention of new operative techniques within the abdomen cavity, the anatomy of abdominal vessels has assumed a great deal of clinical importance. We report here a rare case of formation of an "arterial glomerulus" at the hilum of the right kidney by the branches of right renal artery.

Assessment of quality of life in patients with chronic oral mucosal diseases: a questionnaire-based study.

Context: A validated discipline-specific questionnaire has been developed recently to assess the quality of life (QOL) in patients with chronic oral mucosal diseases.

Objective: Use the Chronic Oral Mucosal Diseases Questionnaire for evaluating a diverse group of patients with chronic oral mucosal disease after therapy.

Design: Prospective convenience sample.

Iron sucrose versus oral iron therapy in pregnancy anemia.

Background: Iron deficiency anemia (IDA) is the most common medical problem in pregnancy. Parenteral iron is a useful treatment, although iron dextran use decreased due to anaphylaxis. Iron sucrose is a newer agent that has overcome the shortcomings of iron dextran.

An evaluation of the Pi analysis in the assessment of anteroposterior jaw relationship.

Objective: This study has investigated two new cephalometric variables, the Pi angle and Pi linear in the evaluation of anteroposterior skeletal discrepancy.

Design: Retrospective cross-sectional study.

Setting: Manipal College of Dental Sciences, Manipal, India

Subjects And Method: A sample of 155 subjects (mean age 19·7 years) were subdivided into skeletal class I, II and III groups based upon ANB angle.

RETRACTED by plagiarism: Highly active antiretroviral therapy induced adverse drug reactions in Indian human immunodeficiency virus positive patients.

Objective: To assess the incidence, severity pattern, causality, predictability and preventability of adverse drug reactions (ADRs) and to identify risk factors for adverse drug reactions in highly active antiretroviral therapy.

Methods: Enrolled patients were intensively monitored for ADRs to highly active antiretroviral therapy. Predictability was assessed based on history of previous exposure to the drug or literature incidence of ADRs.

Ascorbic acid protects against restraint stress-induced memory deficits in Wistar rats.

Objective: Chronic stress has been shown to cause oxidative damage in the central nervous system. Although stress-induced impairments in learning and memory have been studied extensively, very few studies have investigated possible ways to prevent their ill effects. The present work was designed to study the protective effects of ascorbic acid in memory loss induced by chronic restraint stress.

Sternalis muscle revisted in South Indian male cadaver: a case report.

Introduction: Sternalis/rectus sternalis is a rare muscle found in the chest wall. Only 3-5% of the cases are found world wide.

Case Presentation: Here we report the case of Sternalis in the 60-year-old South Indian male cadaver.

Comparison of two dosing regimens of vaginal misoprostol for labour induction: a randomised controlled trial.

Objective: To compare the clinical efficacy of two different dosing regimens of vaginal misoprostol for labour induction.

Material And Methods: This is an open label randomised controlled trial of 100 eligible women with obstetrical or medical indications for labour induction at a secondary level care hospital on the west coast of India. Women were randomised to receive either a single 50 μg dose or multiple 25 μg doses (maximum of three doses) of misoprostol in the posterior vaginal fornix.