6 results match your criteria: "Manipal School of Life Sciences (MSLS)[Affiliation]"
A biomedical perspective of pyocyanin from Pseudomonas aeruginosa: its applications and challenges.
World J Microbiol Biotechnol
February 2024
Department of Public Health & Genomics, Manipal School of Life Sciences (MSLS), Manipal Academy of Higher Education (MAHE), Manipal, Karnataka, 576104, India.
Pyocyanin is a bioactive pigment produced by Pseudomonas aeruginosa. It is an important virulence factor that plays a critical role in P. aeruginosa infections as a redox-active secondary metabolite and a quorum sensing (QS) signaling molecule.
View Article and Find Full Text PDFDecreased expression of CD200 on peripheral blood leukocytes in alcohol dependence.
Alcohol
December 2023
Department of Biomedical Sciences, Tilman J. Fertitta Family College of Medicine, University of Houston, 5055 Medical Circle, Houston, TX, 77204, United States.
Chronic alcohol use induces innate immune genes, which activate the innate immune system. Neuroimmune regulatory proteins [e.g.
View Article and Find Full Text PDFCytotoxicity and radiosensitizing potency of Moscatilin in cancer cells at low radiation doses of X-ray and UV-C.
3 Biotech
June 2021
Department of Plant Sciences, Manipal School of Life Sciences (MSLS), Manipal Academy of Higher Education (MAHE), Manipal, Udupi, Karnataka 576104 India.
Unlabelled: Moscatilin (stilbenoid) is a plant-derived anticancer compound, and it has mostly been isolated from threatened wild species. The present study attempts to evaluate the cytotoxicity of Moscatilin on several cancer cell lines through MTT assay. Additionally, it also aims towards estimating and comparing the radiosensitivity, cell-cycle progression, and apoptotic/necrotic effect induced by Moscatilin on different cell lines.
View Article and Find Full Text PDFPlacebogenomics: A New Concept and Tool for Personalized Medicine and Public Health.
OMICS
February 2021
OMICS: A Journal of Integrative Biology, New Rochelle, New York, USA.
Pseudomonas aeruginosa virulence proteins pseudolysin and protease IV impede cutaneous wound healing.
Lab Invest
December 2020
Department of Cell & Molecular Biology, Manipal School of Life Sciences (MSLS), Manipal Academy of Higher Education (MAHE), Manipal, India.
Article Synopsis
- Cutaneous wound healing involves complex biological processes, with dermal fibroblasts and keratinocytes playing crucial roles in reepithelialization, but pathogenic bacteria like Pseudomonas aeruginosa can hinder this process.
- Research on three virulent strains of P. aeruginosa showed that proteins pseudolysin and protease IV negatively affect fibroblasts, keratinocytes, and endothelial cells, impairing their migration, survival, and the ability to form new blood vessels.
- Pseudolysin and protease IV also induced prolonged inflammation and delayed wound healing in mouse models, suggesting they could be targeted for improved wound management in clinical settings.
Blockchain for Digital Health: Prospects and Challenges.
OMICS
May 2020
UNU-MERIT (United Nations University-Maastricht Economic and Social Research Institute on Innovation and Technology), Maastricht University, Maastricht, The Netherlands.
An open distributed ledger system, blockchain records digital transactions and offers the potential to disruptively transform the way we conduct biomedical research, provide health care, and perform economic transactions. This expert review provides the overarching background, key definitions, prospects and socio-technical challenges at the intersection of blockchain and digital health. In addition, we discuss the tenets of next-generation technology policy for blockchain, drawing from the field of responsible innovation.
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