Exploring Hydrocele of the Canal of Nuck in a Mature Woman: Beyond the Norm.

Timely diagnosis and surgical intervention are crucial in managing hydrocele of the canal of Nuck. A systematic approach, including thorough examination and appropriate imaging, followed by meticulous surgical technique, ensures successful treatment and favorable long-term outcomes for patients.

Aconite Poisoning: From Crisis to Healing.

Early recognition and prompt intervention are crucial in managing aconite poisoning. Rapid treatment with intravenous magnesium sulfate and amiodarone can stabilize severe cardiac arrhythmias. Vigilant monitoring and tailored therapeutic strategies enhance recovery and improve patient outcomes in acute poisoning cases.

Immune checkpoint inhibitor-induced myasthenia gravis, myocarditis, and myositis: A case report.

Key Clinical Message: Immune checkpoint inhibitors can rarely lead to occurrence of myositis, myocarditis, and myasthenia gravis (MG). Early recognition and multidisciplinary management are crucial for optimal outcomes. Vigilance for overlapping toxicities is essential in patients receiving combination immunotherapy.

Sphincter of oddi dysfunction induced by ketamine: A case report.

Key Clinical Message: Chronic ketamine use can lead to sphincter of oddi dysfunction (SOD), causing various hepatobiliary complications. Recognizing substance abuse history is vital for early detection. Timely intervention can prevent irreversible liver and pancreas damage.

Middle meningeal artery embolization for chronic subdural hematoma refractory to Burr hole surgery: A case report.

Middle meningeal artery embolization is a valuable alternative for chronic subdural hematoma refractory to Burr hole surgery. In a 61-year-old patient, this endovascular intervention effectively resolved the hematoma alleviating associated symptoms.

Granulomatosis with polyangiitis mimicking COVID-19 pneumonia: A case report.

Granulomatosis with polyangiitis (GPA), formerly known as Wegener's granulomatosis, is a necrotizing vasculitis characterized by small-to-medium-sized vessel involvement and the presence of antineutrophil cytoplasmic antibodies (ANCA). We present a case of a 26-year-old Asian woman who was transferred to our center from a nearby hospital, where she presented with shortness of breath, tested positive for COVID-19, and was being managed for COVID-19 pneumonia. She also had hemoptysis, skin lesions, and left foot numbness.

Type IV-A choledochal cyst with choledocholithiasis in an adult female: A case report.

A choledochal cyst is a rare congenital anomaly of the biliary system, characterized by bile duct cystic dilatation, typically affecting the common bile duct. Choledochal cysts are generally categorized using the Todani classification system. The typical symptoms are jaundice, abdominal masses, and recurrent abdominal pain.

Aspirin-induced urticaria in a recently diagnosed ischemic stroke patient: A case report and literature review.

Key Clinical Message: NSAIDs may be rare but an important cause of urticarial which should not be missed.

Abstract: The aspirin and urticaria correlation has not been fully understood. The pharmacological inference is suspected to be the diversion of arachidonic acid metabolism.

Cervical spondylotic myelopathy presenting as a "pancake enhancement" on MRI of the spinal cord: A case report and review of literature.

Spondylotic myelopathy involves chronic spinal cord compression from degenerative spine changes presenting a myriad of neurological and pain symptoms. We report a case of cervical myelopathy with transverse pancake-like gadolinium enhancement seen on MRI in a 42-year-old gentleman with progressive bilateral upper extremity numbness, tingling, and impaired gait.

Giant multinodular goiter for 24 years; hidden in a village in Western Nepal.

Here, we present the case of a giant multinodular goiter with retrosternal extension in an old lady with dyspnea for 3 months. The patient was treated with microscopic-assisted total thyroidectomy without any postoperative complications.

Microscopic assisted excision of a rare posterior triangle branchial cyst.

Branchial cyst is a painless mass commonly located in the anterior triangle of the neck. It is rarely found in the posterior triangle of the neck. A computed tomography scan of the neck is important to see the extent of the anomaly and its relationship with the major vessel.

Fine-needle aspiration cytology diagnosis of aspergilloma - A case report.

Fine-needle aspiration cytology, a simple and inexpensive technique can aid in early diagnosis of aspergilloma. Here, we present a case of 55-years-old female with a past history of pulmonary tuberculosis and a right-lung cavitary lesion, diagnosed as aspergilloma.

Pattern of adverse drug reactions reported by the community pharmacists in Nepal.

Unlabelled: The pharmacovigilance program in Nepal is less than a decade old, and is hospital centered. This study highlights the findings of a community based pharmacovigilance program involving the community pharmacists.

Objectives: To collect the demographic details of the patients experiencing adverse drug reactions (ADR) reported by the community pharmacists; to identify the common drugs causing the ADRs, the common types of ADRs; and to carry out the causality, severity and preventability assessments of the reported ADRs.

Pattern and quality of scientific communications on drug safety produced by a regional pharmacovigilance center in Nepal.

Unlabelled: Analyzing the pattern and quality of scientific communications on pharmacovigilance can help the regional centers in Nepal and other developing countries to develop approaches for communicating effectively medicine safety issues. This kind of research is lacking in developing countries.

Objectives: To analyze the pattern and quality of scientific communications on drug safety produced by the regional pharmacovigilance center at western Nepal.

Impact of educational intervention on the pattern and incidence of potential drug-drug interactions in Nepal.

Objective: To study the impact of educational intervention on the pattern and incidence of potential drug-drug interactions (DDIs).

Method: All patients admitted to Internal Medicine wards of Manipal Teaching Hospital during the study period were included. Patient details were collected using a patient profile form and the datum from the filled forms was analyzed using Micromedex electronic database.