Preserving Integrity: Investigating the Influence of Disinfecting Agents on Polymethylmethacrylate Dental Prosthesis Surface Characteristics in Children.

Introduction: In children, polymethylmethacrylate (PMMA) is a commonly used material for fabrication of dental prostheses, such as obturators, removable space maintainers, habit-breaking appliances, removable orthodontic appliances, and removable partial and complete dentures. Regular cleaning of such prostheses is vital for maintaining the health of the oral tissues as well as the longevity of the prosthesis. The chemical method of disinfection, using different chemical cleansers, is commonly used for cleaning a dental prosthesis.

Third molar infections and their impact on systemic health- an awareness study among women degree college students of Udupi City, Karnataka, India.

Introduction: The wisdom teeth usually erupt at the age of 17-25 years leading to the risk of pericoronitis, caries, periodontitis, anterior crowding of teeth and cyst development. Previous studies have reported that the third molar infection is more associated with the age group of 26-35 years and is more commonly reported in the female gender.

Aims: Hence, the aim was to assess knowledge regarding third molar infections among women degree college students.

Novel transcripts of EMT driving the malignant transformation of oral submucous fibrosis.

Oral submucous fibrosis (OSF) is a chronic, progressive, and fibrotic condition of the oral mucosa that carries an elevated risk of malignant transformation. We aimed to identify and validate novel genes associated with the regulation of epithelial-to-mesenchymal transition (EMT) in OSF. Genes regulating EMT were identified through differential gene expression analysis, using a LogFC threshold of -1 and + 1 and a padj value < 0.

Efficacy of Rapid Salivary C-Reactive Protein Test to Assess Early Changes in Malignancy in the Oral Cavity and Its Utility in Screening for Oral Cancer.

The present study aimed to test the efficacy of the chair-side rapid salivary C-reactive protein assay kit in differentiating oral potentially malignant disorders (OPMDs) and oral cancer from normal mucosa using whole salivary samples. In this study, unstimulated saliva samples of cases (OPMDs and oral cancer) and controls (systemically healthy subjects) were used to detect CRP levels using a novel colorimetric, quantitative rapid assay kit. Kruskal-Wallis ANOVA with a post hoc Dunn's test were applied to determine the difference in the mean and SD values between the case and control groups.

Impact of chlorine dioxide and chlorhexidine mouthwashes on friction and surface roughness of orthodontic stainless steel wires: an in-vitro comparative study.

Objectives: Good oral hygiene measures are important for successful orthodontic treatment. They involve various types of mouthwashes which have been reported to cause alteration of mechanical properties of archwires. This study aimed to evaluate the effects of a new kind of chlorine-dioxide-containing mouthwash on the mechanical properties and surface morphology of stainless steel orthodontic archwires against the already prevalent chlorhexidine mouthwash in the market.

The science of printing and polishing 3D-printed dentures.

Objective: To analyze the effectiveness of various techniques available for printing, finishing and polishing of 3D printed prosthesis.

Methods: The articles were selected from electronic databases including PubMed and Scopus. Recently, lot of advancements have been observed in the field of 3D printing in dentistry.

Methylenetetrahydrofolate Reductase Gene Polymorphism as a Risk Factor for Coronary Artery Disease.

Hyperhomocysteinemia (HHcy) is one of the factors contributing to the pathogenesis of coronary artery disease (CAD). Besides nutritional deficiency disorders, genetic polymorphism predominantly related to point mutation in the gene coding for Methylenetetrahydrofolate reductase (MTHFR), a key enzyme in the metabolism methionine-homocysteine (Hcy) has been implicated in HHcy. PubMed survey related to MTHFR gene polymorphism in CAD retrieved 143 articles from which 20 were selected in which MTHFR gene polymorphism and Hcy were estimated.

Radiomorphometric Parameters in Mandibular Panoramic Radiographs of Hypothyroid Patients: A Cross-Sectional Study.

Purpose: Thyroid hormones have a catabolic effect on bone mineral homeostasis. Hypothyroid patients have shown changes in bone mineral density with increased risk for osteoporosis and bone fractures. Radiomorphometric parameters on panoramic images are good indicators of bone mineral density.

Comparative Evaluation of Deciduous and Permanent Coronal Caries Using Polarizing Light Microscopy and Scanning Electron Microscopy.

Dental caries causes mineral loss and organic damage to teeth. Understanding caries and dentin pulp reactions is crucial for effective caries management strategies. There is a lack of knowledge regarding the microscopic and ultramicroscopic changes that occur during caries destruction and reactive changes.

Volumetric Comparison of the Temporomandibular Joint Space in Skeletal Class I and II Patients Using Cone-Beam Computed Tomography: A Cross-Sectional Study.

Introduction: The temporomandibular joint (TMJ) is one of the most intricate anatomical entities within the human body and is clinically relevant in the field of dentistry. Therefore, the present study aimed to conduct a three-dimensional (3D) volumetric comparison of the TMJ space in skeletal Class I and II patients using cone-beam computed tomography (CBCT).

Materials And Methods: This cross-sectional, retrospective study was conducted on 40 CBCT records divided into skeletal Class I and skeletal Class II patients.

Impact of Platelet-rich Plasma and Platelet-rich Fibrin in Mandibular Third Molar Extraction: A Systematic Review.

Aim: This study aims to evaluate the impact of platelet-rich fibrin (PRF) and platelet-rich plasma (PRP) on pain, swelling, trismus, soft tissue healing and bone regeneration following mandibular third molar extraction.

Material And Methods: A systematic review was conducted from a period of January 2014 to June 2024 using PRISMA guidelines. The search strategy included databases such as Scopus, PubMed, Google Scholar, and Cochrane Central Register of Controlled Trials, using key terms related to "PRF", "PRP", oral surgery, and third molars.

The Prognostic Value of Preoperative Total Cholesterol in Surgically Treated Oral Cavity Cancer.

Background: With growing evidence linking lipid profile changes to tumor development and cancer prognosis, we investigated the prognostic significance of preoperative serum total cholesterol (TC) levels in patients with oral cavity squamous cell carcinoma (OSCC) undergoing surgical treatment.

Methods: We conducted a retrospective observational study involving 310 patients with primary OSCC who received surgery at our hospital from January 2009 to December 2018. Receiver operating characteristic curve analysis was performed to determine the optimal preoperative TC cutoff value, with the Youden Index employed as the optimization criterion to maximize the sum of sensitivity and specificity.

Prognostic Utility of the Modified Systemic Inflammation Score for Patients Undergoing Oral Cavity Cancer Surgery.

Background/objectives: Chronic inflammation significantly contributes to human malignancies. We investigated the prognostic significance of the preoperative modified systemic inflammation score (mSIS) in patients with primary oral cavity squamous cell carcinoma (OCSCC).

Methods: We retrospectively reviewed data from 320 OCSCC patients who underwent curative surgery between 2007 and 2017.

Investigating Oral Cancer Awareness Among Medical and Dental Students: A Cross-Sectional Study in the South Canara Region of India.

Oral cancer is responsible for increased mortality, especially in the Indian subcontinent. Habits like smoking and tobacco chewing are among the most common causes of oral cancer. Previously, these habits were seen mainly in the elderly; however, the trends have seemed to increase in the younger generation.

Preferences and choice in clinical decision-making with the help of time trade-off and standard gamble techniques among periodontally compromised patients - A cross-sectional study.

Background: To assess the validity of time trade-off (TTO) and standard gamble (SG) techniques of utility valuation among patients with periodontal problems by assessing their relation to two logical constructs; Gingival Index (GI) and Oral Health Impact Profile (OHIP) Questionnaire.

Materials And Methods: Two hundred and one patients aged 18 years old and above, who visited a tertiary care hospital for treatment/consultation were included. A questionnaire was administered to record the TTO, SG, and OHIP.

Substance P-A neuropeptide regulator of periodontal disease pathogenesis and potential novel therapeutic entity: A narrative review.

Substance P (SP), a neuropeptide primarily released by neurons, has emerged as a key player in the intricate network of factors governing periodontal inflammation, immune responses, bone metabolism, and tissue regeneration. Due to its multifaceted role, it may be explored for its potential participation in periodontal therapeutic strategies. The databases, PubMed/MEDLINE, and SCOPUS were searched for all published articles on SP, its role in inflammation, and periodontal disease.

Evaluation of an interprofessional collaborative practice training module for the management of children with autism spectrum disorder.

Background: Protocols instituted for behavioral treatment and skills training programs for the management of autism spectrum disorder (ASD) suffer from lack of collaborative approaches. The tenets of interprofessional collaborative practice (IPCP) focus on preparing a panel of health care professionals (HCPs) from different professions who can work together to enable the common goal of ensuring that children with ASD can participate in society. This study was designed to pilot this approach through an IPCP training module on ASD for care providers from multiple professions.

Biological and chemical properties of new multi-functional root canal irrigants.

Objectives: To evaluate the efficacy of multi-functional root canal irrigating solutions in the removal of canal wall smear layers, antibacterial activity, cytotoxicity, and tissue dissolution efficacy.

Methods: Forty single-rooted teeth were mechanically instrumented and irrigated with Triton, EndoJuice™, EDTA, and 0.9 % saline.

Effect of Age, Hot Beverages and Tobacco Related Products on Buccal Epithelial Cells of Cigarette Smokers and non-Smokers in Ajman, UAE.

Objective: This study aimed to find out the effect of age, hot beverages and tobacco related products on buccal mucosa cells between cigarette smokers and non-smokers in Ajman, UAE.

Methods: A total of 122 samples were collected, with demographic data including age, hot beverage consumption, cigarette smoking and other tobacco practice using pre-designed questionnaires. Buccal cells were collected, stained, and screened for micronuclei (MN) under a microscope and two evaluators independently assessed all the slides.

Dental Practitioners' Knowledge and Attitudes Toward the Etiology, Diagnosis, and Treatment of Peri-Implantitis.

The objective of this study was to assess the level of knowledge and attitude about the etiology, diagnosis, and management of peri-implantitis among dental practitioners. An online cross-sectional study on 303 dentists in Saudi Arabia was conducted. A closed-ended survey consisting of 28 questions was designed.

Association of maxillofacial injuries with traumatic brain injuries in paediatric patients: a case-control study.

Background: Traumatic brain injuries (TBIs) are among the most challenging conditions to accurately diagnose in children, and many TBIs are underdiagnosed. Patients with maxillofacial injury may be at risk for TBI. The objective of this study was to analyse the association between maxillofacial injuries and TBI among paediatric patients.

The effect of varying thicknesses of mineral trioxide aggregate (MTA) and Biodentine as apical plugs on the fracture resistance of teeth with simulated open apices: a comparative study.

Background: This study evaluates the fracture resistance of apical plugs created from Biodentine and mineral trioxide aggregate (MTA) in thicknesses of 3 and 5 mm within simulated open apex tooth models.

Methods: Fifty human maxillary central incisors were obtained from a pool of freshly extracted teeth. In order to replicate open apices without cavity preparation, ten teeth in the control group received apical-to-coronal preparation with Peeso reamers.

Dental management of people with congenital hemophilia: An integrative review of case reports and case series from a global scenario.

Objective: To analyze the various dental management strategies adopted to manage patients with hemophilia in a dental clinical setup.

Methods: An electronic database search was carried out using MEDLINE by PubMed, Scopus, Google Scholar, Web of Science, and EMBASE databases from January 2000 to August 2023 for case reports and case series published in English language. Case reports addressing the dental treatments for people with hemophilia A/hemophilia B were included.

Effect of herbal toothpaste on the colour stability, surface roughness, and microhardness of aesthetic restorative materials-an in vitro study.

Objective: To evaluate the in vitro effects of two commonly used commercial herbal toothpastes (Dabur Meswak and Patanjali Dant Kanti) on the colour stability, surface texture, and microhardness of two commonly used aesthetic restorative materials, i.e., nanofilled composite and resin-modified glass ionomer cement (NFC and RMGIC).