Systematic evaluation of clinical practice guidelines for pharmacogenomics.

Aim: To systematically assess methodological quality of pharmacogenomics clinical practice guidelines.

Methods: Guidelines published through 2017 were reviewed by at least three independent reviewers using the AGREE II instrument, which consists of 23 items grouped into 6 domains and 2 items representing an overall assessment. Items were assessed on a seven-point rating scale, and aggregate quality scores were calculated.