539 results match your criteria: "Manchester Medical School[Affiliation]"
BMC Nephrol
January 2025
Rochdale Care Organisation, Northern Care Alliance NHS Foundation Trust, Rochdale, England.
Background: One million patients are estimated to have undiagnosed chronic kidney disease (CKD) in England. Clinical coding in CKD is associated with improved management and lower acute kidney injury (AKI), unscheduled care and mortality risk. Primary care's role in coding CKD is well documented.
View Article and Find Full Text PDFWorld J Transplant
December 2024
Department of Renal Medicine, Manchester University NHS Foundation Trust, Manchester M13 9WL, United Kingdom.
Background: Focal segmental glomerulosclerosis (FSGS) often recurs after transplantation, leading to graft dysfunction and graft loss. Patients who have lost prior grafts due to recurrence are at particularly high risk of re-recurrence in subsequent grafts. Rituximab and plasma exchange have been used pre-emptively to prevent post-transplant recurrence.
View Article and Find Full Text PDFJ Heart Lung Transplant
November 2024
Division of Cardiovascular and Thoracic Surgery, Department of Surgery, Duke University Medical Center, Durham, North Carolina; Duke Clinical Research Institute, Durham, North Carolina.
Background: Understanding donor factors associated with successful lung transplantation (LTx) following donation after circulatory death (DCD) is important in optimizing donor management. In this study, we examined critical care and ventilatory factors associated with DCD LTx and allograft survival using a unique detailed donor management database.
Methods: The Donor Management Goals national registry was queried for DCD donors between January 2016 and July 2023.
J Intensive Care Soc
November 2024
Department of Speech, Voice and Swallowing, Wythenshawe Hospital, Wythenshawe, UK.
Background: Dysphagia places a substantial burden on the critically ill, affecting 12%-84% of this cohort, and is independently associated with worse outcomes. Pharyngeal electrical stimulation (PES-treatment) is a novel dysphagia therapy with an emerging evidence base. This retrospective observational study describes our dysphagia service and reports the use of PES-treatment as a standard of care in recovering critically ill patients at a single-site tertiary UK hospital.
View Article and Find Full Text PDFJ Thorac Cardiovasc Surg
November 2024
Division of Cardiovascular and Thoracic Surgery, Department of Surgery, Duke University, Durham, NC.
Background: Current risk-adjusted models for predicting primary graft dysfunction (PGD) following lung transplantation (LTx) do not include bedside donor critical care data. Donor management goals (DMGs) represent predefined critical care endpoints aimed at optimizing multiorgan donor management. Here we sought to identify novel predictors to better understand the relationship between donor management and PGD following LTx.
View Article and Find Full Text PDFPain
October 2024
Centre for Epidemiology Versus Arthritis, Centre for Musculoskeletal Research, The University of Manchester, Manchester, United Kingdom.
Semin Thorac Cardiovasc Surg
September 2024
Division of Cardiovascular and Thoracic Surgery, Department of Surgery, Duke University Medical Center, Durham, North Carolina. Electronic address:
Due to criticism regarding undue adherence to fixed geographic boundaries, the Lung Allocation Score system was recently replaced by the more holistic allocation via continuous distribution. This review highlights the historical evolution of US lung allocation paradigms, outlines rationale for continuous distribution under the Composite Allocation Score system and discusses expected implications of this new system.
View Article and Find Full Text PDFNeurooncol Adv
July 2024
Department of Neurosurgery, Salford Royal NHS Foundation Trust, Greater Manchester Neurosciences Centre, Manchester, UK.
Background: Epileptic seizures commonly burden low-grade glioma (LGG) patients and negatively impact quality of life, neurocognition, and general patient health. Anti-seizure medications (ASMs) are used to manage seizures but can result in undesired side effects. Our aim was to report our experience in epilepsy in one of the largest case series of LGG patients (reclassified in accordance with the WHO 2021 classification).
View Article and Find Full Text PDFCureus
July 2024
Trauma and Orthopaedics, Wythenshawe Hospital, Manchester University NHS Foundation Trust, Manchester, GBR.
Introduction Tourniquets are vital devices in orthopaedic surgery that aid in creating a bloodless field. While they reduce operative time and outcomes, improper use can lead to severe complications. The British Orthopaedic Association Standards for Trauma (BOAST) offers guidelines for safe intraoperative tourniquet usage, emphasising proper application and accurate documentation.
View Article and Find Full Text PDFSkin Health Dis
August 2024
Mid Cheshire NHS Foundation Trust Macclesfield UK.
Clin Exp Dermatol
November 2024
Department of Dermatology, Salford Royal Hospital, Salford, UK.
Br J Oral Maxillofac Surg
June 2024
Department of Orthopaedic Surgery, Rush University Medical Center, Chicago, IL, USA.
Temporomandibular disorders include a wide spectrum of extra-articular and intra-articular conditions affecting the temporomandibular joint (TMJ). In salvage cases involving intra-articular end-stage disease, alloplastic temporomandibular joint replacement (TMJR) is a management option which can be utilised to rehabilitate a disabled joint's function and form. Whilst post-TMJR infection is rare, it is one of the most serious complications.
View Article and Find Full Text PDFClin Breast Cancer
June 2024
The Nightingale Centre, Wythenshawe Hospital, Manchester University NHS Foundation Trust, Manchester, UK; Division of Cancer Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Academic Health Science Centre, Manchester, UK.
Purpose: Due to restrictions on breast clinic appointments during the Covid-19 pandemic, a triage process was introduced for new patient referrals. The robustness of this process was examined by analysing the incidence of cancer diagnosis and wait times to treatment.
Methods: Patients were triaged by secondary care consultant surgeons to an urgent appointment if they had high-risk symptoms based on prespecified guidelines eg, a lump or previous cancer.
Med Teach
December 2024
Department of Medical Education, Division of Medical Education, The University of Manchester, Manchester, United Kingdom of Great Britain and Northern Ireland.
Background And Objectives: The rational for the Somaliland national harmonised curriculum (NHC) was driven by shared concern about the quality of medical education.
Process: The Ministry of Education and Science and the Ministry of Health Development produced a Medical Education Policy 2018. Policy objectives included the development of the NHC and accreditation for medical schools that met the standards of the World Federation for Medical Education (WFME).
Eur J Hum Genet
March 2024
Cardiff University School of Medicine, Institute of Medical Genetics, University Hospital of Wales, Cardiff, UK.
J Heart Lung Transplant
May 2024
Division of Cardiovascular and Thoracic Surgery, Department of Surgery, Duke University Medical Center, Durham, North Carolina.
Background: Reoperative lung transplantation (LTx) survival has improved over time such that a growing number of patients may present for third-time LTx (L3Tx). To understand the safety of L3Tx, we evaluated perioperative outcomes and 3-year survival after L3Tx at a high-volume US LTx center.
Methods: This retrospective study included all patients who underwent bilateral L3Tx at our institution.
Respir Med Res
November 2023
Division of Infection, Immunity and Respiratory Medicine, School of Biological Sciences, The University of Manchester, Manchester Academic Health Science Centre, UK; Manchester Adult Cystic Fibrosis Centre, Manchester University NHS Foundation Trust, Manchester, UK.
Clin Ther
January 2024
Department of Health Data Science, University of Liverpool, Liverpool, United Kingdom.
BMJ Open
November 2023
School of Medicine Dentistry and Nursing, University of Glasgow, Glasgow, UK.
Objectives: The number of UK graduates choosing General Practice training remains significantly lower than the current numbers required to meet the demands of the service. This work aims to explore medical students' perceptions of General Practice, experiences which lead to the development of these perceptions, and the ultimate impact of these on career intention.
Design: This mixed-methods, qualitative study used focus groups, semistructured interviews, longitudinal audio diary data and debrief interviews to explore and capture the experiences and perceptions of students in their first and penultimate years of university.
Cureus
September 2023
Trauma and Orthopaedics, Salford Royal NHS Foundation Trust, Manchester, GBR.
Aims All English major trauma centres (MTCs) offer rib fixation, which the National Institute for Health and Care Excellence (NICE) guidance indicates in patients with multiple rib fractures or a flail segment; however, the data does not identify the appropriate patients. Our aims were to establish improvements in outcomes following rib fixation at our trust and then determine if the rib fixation service has improved. Methods We performed a matched cohort study whereby 32 patients who underwent rib fixation were independently matched with conservatively managed patients.
View Article and Find Full Text PDFInt Ophthalmol
November 2023
Manchester Royal Eye Hospital, Oxford Road, Manchester, M13 9WL, UK.
Purpose: To assess the impact of the junior doctors' industrial action on one of the largest emergency eye departments (EED) in the United Kingdom.
Methods: We compared staff allocation, patient presentation, time in streaming, time in the department, the Manchester Triage System (MTS) score, number of eye emergencies and follow-up care of patients who attended the EED in the Manchester Royal Eye Hospital (MREH) during the 3-day industrial action (13-15 March 2023) compared with control periods 2 weeks before and 2 weeks after the industrial action.
Results: During the industrial action, there were almost 1.
Gastroenterol Hepatol Bed Bench
January 2023
Gastroenterology Department, Luton & Dunstable University FT Hospital, Luton, UK.
Aim: The aim of this work was to highlight the impact and hidden costs incurred by the NHS in supporting this management process.
Background: Coeliac disease (CD) is a common auto-immune condition which affects around 1% of the general population. In 2005 there was a drive by the government to discharge patients with CD from specialist hospital follow up to community-based management to improve cost efficiency.
J Am Soc Echocardiogr
October 2023
University of Manchester Medical School, Manchester, United Kingdom; Department of Cardiology, Wythenshawe Hospital, Manchester, United Kingdom. Electronic address:
The prevalence of type 2 diabetes mellitus (T2DM) is steadily rising worldwide due to an increasingly sedentary lifestyle combined with unhealthy food habits. Currently, the burden of diabetes on healthcare systems is unprecedented and rising daily. Several observational studies and randomized controlled trials provide clinical evidence that T2DM remission is possible by adopting dietary interventions and a strict exercise training protocol.
View Article and Find Full Text PDFJ Plast Reconstr Aesthet Surg
August 2023
CLEFT - Bridging the Gap, Chelmsford, United Kingdom; North Thames Cleft Centre, Great Ormond Street Hospital for Children NHS Foundation Trust, London and St Andrew's Centre, Broomfield Hospital, Chelmsford, Essex, United Kingdom.
Background: There is a disparity in access, quality, and sustainability of cleft care in low and middle income countries, where burden of disease is greatest. CLEFT-Bridging the Gap (registered charity number: 1194581) is a UK-based charity that aims is to solve this through teaching, empowerment and development of sustainable cleft services. A Student Section, composed of medical, dental and speech and language therapy students, was established to support these endeavours through fundraising.
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