74 results match your criteria: "Manchester Institute for Collaborative Research on Ageing.[Affiliation]"

Peer-volunteering schemes can facilitate health improvement via increasing physical activity levels. Understanding what motivates peer volunteers is valuable for the feasibility of volunteering schemes. This scoping review aims to explore the motivations of peer volunteers aged over 50 who participate in programs that promote physical activity.

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Article Synopsis
  • The study explored the experiences of older adults and service providers involved in a UK physical activity program designed through participatory approaches.
  • Four main themes were identified: tailored activities that encouraged participation, accessibility of sessions, enjoyment and perceived benefits, and support needs for service deliverers.
  • The findings suggest that involving older adults in the program's design enhances satisfaction and engagement, but ongoing support and resources are essential for sustainability.
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Objectives: Hearing and vision impairments are associated with cognitive decline and dementia risk. Explanations for this include age-related processes impacting on sensory and cognitive function (common cause), or sensory impairments having a direct or indirect impact on cognition via social engagement, depression and physical activity (cascade). We tested whether associations between hearing, vision and episodic memory were mediated by allostatic load, social engagement, depression and physical activity.

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Exergames for falls prevention in sheltered homes: a feasibility study.

Front Public Health

July 2024

Division of Psychology and Mental Health, Academic Health Science Centre, The University of Manchester, Manchester, United Kingdom.

Introduction: Falls prevention is a global priority given its substantial impact on older adults and cost to healthcare systems. Advances in telerehabilitation technology such as `exergaming' show potential for delivering accessible, engaging exercise programs for older adults. This study aimed to establish the feasibility, acceptability and usability of exergaming in sheltered housing.

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Effectiveness of dance interventions for falls prevention in older adults: systematic review and meta-analysis.

Age Ageing

May 2024

National Institute for Health and Care Research, Older People and Frailty Policy Research Unit, The University of Manchester, Manchester M13 9PL, UK.

Introduction: Fall prevention is a global health priority. Strength and balance exercise programmes are effective at reducing falls. Emerging literature suggests dance is an enjoyable and sociable form of exercise.

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Increasing physical activity (PA) and/or decreasing sedentary behaviors is important in the delay and prevention of long-term conditions. PA can help maintain function and independence and decrease the need for hospitalization/institutionalization. Activity rates often decline in later life resulting in a need for interventions that encourage uptake and adherence through the use of Behavior Change Techniques (BCTs).

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Article Synopsis
  • - Possible sarcopenia, characterized by low muscle strength, is more prevalent in older adults living in the community compared to confirmed or severe cases, highlighting a need for effective intervention strategies.
  • - There is a lack of non-pharmacological interventions for possible sarcopenia, especially regarding health education, as older adults show low awareness of the condition, prompting the need for immediate outreach methods, such as social media.
  • - This study outlines a protocol for designing a social media-based intervention aimed at preventing sarcopenia, involving two phases of co-designing with community members, including focus groups and interviews to refine the intervention approach.
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For older people, physical inactivity increases fall risk as well as other preventable health conditions. Despite the well-documented benefits of physical activity, uptake and adherence continue to challenge efforts aimed at increasing physical activity and reducing falls. Nested within a randomized controlled trial, this study reports on the factors influencing the physical activity behavior of people, aged between 70 and 90 years, engaged in , a home-based balance exercise program proven to reduce falls in the community.

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Background: The COVID-19 pandemic has accelerated the shift toward the digital provision of many public services, including health and social care, public administration, and financial and leisure services. COVID-19 services including test appointments, results, vaccination appointments and more were primarily delivered through digital channels to the public. Many social, cultural, and economic activities (appointments, ticket bookings, tax and utility payments, shopping, etc) have transitioned to web-based platforms.

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Free-Cog revisited: the diagnostic contribution of cognitive and executive function.

Neurodegener Dis Manag

December 2023

Greater Manchester Mental Health NHS Foundation Trust, University of Manchester, UK; National Clinical Director for Dementia & Older People's Mental Health; Director, Manchester Institute for Collaborative Research on Ageing.

To examine Free-Cog, a recently described, hybrid screening instrument, as separate tests of cognitive (Free-Cog-Cog) and executive function (Free-Cog-Exec) to see if this improved screening accuracy for cognitive impairment compared with standard Free-Cog. Free-Cog-Cog and Free-Cog-Exec were combined using Boolean logical 'AND' and 'OR' operators (serial and parallel combination), and also used to construct a stepwise decision tree. Serial combination improved specificity and positive predictive value whereas parallel combination improved sensitivity, typical findings with these operators.

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Background: The overall level of negative affect (NeA) has been linked to impaired health. However, whether the diurnal timing of NeA matters and whether the NeA-health relationship is mediated by sleep quality remain unclear.

Methods: Using a longitudinal dataset (2006, 2009 and 2014 waves) consisting of 1959 participants, we examined the within-person impact of both bedtime NeA and non-bedtime NeA measured by Day Reconstruction Method (DRM) on subjective health measured by Visual Analogue Scale (VAS), and the mediating effect of sleep quality on the NeA-health relationships by fixed effect models.

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Background: The Active Connected Engaged [ACE] study is a multi-centre, pragmatic, two-arm, parallel-group randomised controlled trial [RCT] with an internal pilot phase. The ACE study incorporates a multi-level mixed methods process evaluation including a systems mapping approach and an economic evaluation. ACE aims to test the effectiveness and cost-effectiveness of a peer-volunteer led active ageing intervention designed to support older adults at risk of mobility disability to become more physically and socially active within their communities and to reduce or reverse, the progression of functional limitations associated with ageing.

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Background: Nearly 50 million people worldwide have dementia and the increasing numbers requiring end-of-life and palliative care, has led to national efforts to define standards of care for this patient group. Little research, however, has been done to date about the experience of hospice care for people with dementia accessing these services. This study explores the views of hospice dementia care for bereaved carers of people with dementia and hospice clinicians.

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Acceptability of physical activity signposting for pre-frail older adults: a qualitative study to inform intervention development.

BMC Geriatr

October 2023

National Institute for Health and Care Research, Applied Research Collaboration Greater Manchester, School of Health Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, M13 9PL, UK.

Frailty is a medical condition common in older adults characterised by diminished strength and reduced physiologic function in which individuals are more vulnerable to multiple adverse health outcomes. Pre-frailty is an intermediate stage associated with some minor health outcomes. However, the main risk is progression toward moderate/severe frailty.

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Human Mast Cells Upregulate Cathepsin B, a Novel Marker of Itch in Psoriasis.

Cells

August 2023

Lydia Becker Institute of Immunology and Inflammation, Division of Musculoskeletal and Dermatological Sciences, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester M13 9PT, UK.

Mast cells (MCs) contribute to skin inflammation. In psoriasis, the activation of cutaneous neuroimmune networks commonly leads to itch. To dissect the unique contribution of MCs to the cutaneous neuroinflammatory response in psoriasis, we examined their density, distribution, relation to nerve fibres and disease severity, and molecular signature by comparing RNA-seq analysis of MCs isolated from the skin of psoriasis patients and healthy volunteers.

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Objectives: Hospices are regarded as gold standard providers of end-of-life care. The term hospice, however, is broadly used, and can describe a type of care offered in a variety of health care services (e.g.

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Non-pharmacological interventions for community-dwelling older adults with possible sarcopenia or sarcopenia: a scoping review.

Arch Gerontol Geriatr

September 2023

School of Health Sciences, Faculty of Biology, Medicine & Health, The University of Manchester, Manchester, UK; Manchester Institute for Collaborative Research on Ageing, Manchester, UK; Manchester Academic Health Science Centre, Manchester, UK; Manchester University NHS Foundation Trust, Manchester, UK. Electronic address:

Background: Sarcopenia is a progressive, age-related muscle disease that, if left untreated, imposes significant personal, social, and economic burdens.

Objective: To compile and document the nature and extent of existing studies exploring non-pharmacological interventions as a strategy to prevent or treat possible sarcopenia or sarcopenia in community-dwelling older adults.

Method: Thirteen databases were searched up from January 2010 to March 2023 and filters were limited to English and Chinese language.

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Article Synopsis
  • This scoping review aims to explore non-pharmacological interventions for preventing sarcopenia among older adults living in the community, with the goal of reducing illness and improving life quality.
  • The methodology involves a comprehensive search of various databases and grey literature, focusing on studies published from 2010 to 2022, and will follow specific guidelines to ensure thoroughness and clarity in reporting.
  • Findings will be analyzed to summarize existing research, highlight gaps, and inform future studies, with results shared in academic journals and relevant community forums.
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Article Synopsis
  • The study explored how changes in self-reported hearing over eight years affect cognitive function, particularly episodic memory, among older adults.
  • Data was gathered from two major studies (ELSA and HRS) involving nearly 11,000 participants aged 50+, utilizing growth curve modeling to analyze hearing trajectories and their impact on memory.
  • Results showed that those with poor or declining hearing had worse memory scores, while individuals with stable or improving hearing scored better in memory tests, indicating a clear link between hearing health and cognitive function.
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Equity in the Allocation of General Practitioner Resources in Mainland China from 2012 to 2019.

Healthcare (Basel)

January 2023

Center for Health Management and Policy Research, Cheeloo College of Medicine, School of Public Health, Shandong University, Jinan 250012, China.

Background: General practitioners (GPs) play a vital role in primary health care services and promoting the health equity of residents, but there is a paucity of evidence on equity in the allocation of GP resources in mainland China. This study explores equity in the allocation of GP resources from 2012 to 2019 in mainland China.

Methods: We used GP data from 31 provinces, autonomous regions, and municipalities in mainland China.

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Background: The WHO has warned that substandard and falsified medicines threaten health, especially in low and middle-income countries (LMICs). However, the magnitude of that threat for many medicines in different regions is not well described, and high-quality studies remain rare. Recent reviews of studies of cardiovascular and diabetes medicine quality recorded that 15.

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Background: A sedentary lifestyle increases the risk of adverse health outcomes and frailty,particularly for older adults. To reduce transmission during the COVID-19 pandemic, people were instructed to stay at home, group sports were suspended, and gyms were closed, thereby limiting opportunities for physical activity. Whilst evidence suggests that physical activity levels reduced during the pandemic, it is unclear whether the proportion of older adults realising the recommended minimum level of physical activity changed throughout the various stages of lockdown.

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Allostatic load and risk of hearing impairment.

Brain Behav Immun Health

November 2022

Global Development Institute and Manchester Institute for Collaborative Research on Ageing, University of Manchester, Manchester, UK.

Background: Prevention of hearing loss via addressing potentially modifiable risk factors may offer means of reducing the global burden of hearing loss. Prior studies reported associations between individual markers of inflammation and risk of hearing impairment. Allostatic load is an index of cumulative physiological stressors, including inflammation, to multiple biological systems.

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Later life relationships and in particular the role of sex within them, have often been neglected in research due to assumptions of decline and sexlessness. We contribute to a growing body of work which counters these stereotypes by examining sexual scripts within the socio-cultural context of later life relationships. We analyzed open-text comments from the English Longitudinal Study of Aging (ELSA) collected as part of a self-completion questionnaire.

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'A Lot of People Just Go for Walks, and Don't Do Anything Else': Older Adults in the UK Are Not Aware of the Strength Component Embedded in the Chief Medical Officers' Physical Activity Guidelines-A Qualitative Study.

Int J Environ Res Public Health

August 2022

National Institute for Health and Care Research Applied Research Collaboration Greater Manchester, Division of Nursing Midwifery and Social Work, Faculty of Biology, Medicine and Health, School of Health Sciences, The University of Manchester, Manchester M13 9PL, UK.

Strength recommendations have been embedded within the UK's Chief Medical Officers' physical activity guidelines since 2011. In 2019, they were given a more prominent position in the accompanying infographic. However, there is limited evidence that these recommendations have been successful in their population-wide dissemination.

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