Antioxidant Activity of Protein Hydrolysates from Redlip Mullet () Muscle and Byproducts.

Fish muscle and byproducts represent a valuable source of bioactive compounds, with their protein hydrolysates exhibiting noteworthy antioxidant properties. This study assessed the antioxidant activity of protein hydrolysates derived from the muscle and byproducts of redlip mullet (), utilizing different proteases (Neutrase, Alcalase, and Protamex). Hydrolysates were prepared from various parts of the fish, including muscle (white and red meat) and byproducts (frames, head, viscera, fins, skin, and scales).

With a little help from my (neighbouring) friends. 'Border region patient mobility' in the European Union: A policy analysis.

Increased disparities in income and health care expenditure across EU countries may lead to an increase in patient mobility, which may, in turn, call for more action by the EU and its Member States. At present, patient mobility (or cross-border healthcare) is still a marginal phenomenon but is deemed to increase in the future. In this paper we examine border region patient mobility, defined as patients receiving care in a neighbouring country within a certain proximity.

The war on drugs is a war on us: young people who use drugs and the fight for harm reduction in the Global South.

In the Global South, young people who use drugs (YPWUD) are exposed to multiple interconnected social and health harms, with many low- and middle-income countries enforcing racist, prohibitionist-based drug policies that generate physical and structural violence. While harm reduction coverage for YPWUD is suboptimal globally, in low- and middle-income countries youth-focused harm reduction programs are particularly lacking. Those that do exist are often powerfully shaped by global health funding regimes that restrict progressive approaches and reach.

Enhancing misinformation correction: New variants and a combination of awareness training and counter-speech to mitigate belief perseverance bias.

Belief perseverance bias refers to individuals' tendency to persevere in biased opinions even after the misinformation that initially shaped those opinions has been retracted. This study contributes to research on reducing the negative impact of misinformation by mitigating the belief perseverance bias. The study explores the previously proposed awareness-training and counter-speech debiasing techniques, further developing them by introducing new variants and combining them.

Optimizing Digital Tools for the Field of Substance Use and Substance Use Disorders: Backcasting Exercise.

Background: Substance use trends are complex; they often rapidly evolve and necessitate an intersectional approach in research, service, and policy making. Current and emerging digital tools related to substance use are promising but also create a range of challenges and opportunities.

Objective: This paper reports on a backcasting exercise aimed at the development of a roadmap that identifies values, challenges, facilitators, and milestones to achieve optimal use of digital tools in the substance use field by 2030.

Insights into how universal, tax-funded, single payer health systems manage their waiting lists: A review of the literature.

A conspicuous consequence of gatekeeping arrangements in universal, tax-funded, single-payer health care systems is the long waiting times. Besides limiting equal access to care, long waiting times can have a negative impact on health outcomes. Long waiting times can create obstacles in a patient's care pathway.

Effective mitigation of the belief perseverance bias after the retraction of misinformation: Awareness training and counter-speech.

The spread and influence of misinformation have become a matter of concern in society as misinformation can negatively impact individuals' beliefs, opinions and, consequently, decisions. Research has shown that individuals persevere in their biased beliefs and opinions even after the retraction of misinformation. This phenomenon is known as the belief perseverance bias.

Harnessing a clinician-led governance model to overcome healthcare tribalism and drive innovation: a case study of Northumbria NHS Foundation Trust.

Purpose: Healthcare tribalism refers to the phenomenon through which different groups in a healthcare setting strictly adhere to their profession-based silo, within which they exhibit stereotypical behaviours. In turn, this can lead to deleterious downstream effects upon productivity and care delivered to patients. This study highlights a clinician-led governance model, implemented at a National Health Service (NHS) trust, to investigate whether it successfully overcame tribalism and helped drive innovation.

Machine unlearning: linear filtration for logit-based classifiers.

Recently enacted legislation grants individuals certain rights to decide in what fashion their personal data may be used and in particular a "right to be forgotten". This poses a challenge to machine learning: how to proceed when an individual retracts permission to use data which has been part of the training process of a model? From this question emerges the field of , which could be broadly described as the investigation of how to "delete training data from models". Our work complements this direction of research for the specific setting of class-wide deletion requests for classification models (e.

Cadence Detection in Road Cycling Using Saddle Tube Motion and Machine Learning.

Most commercial cadence-measurement systems in road cycling are strictly limited in their function to the measurement of cadence. Other relevant signals, such as roll angle, inclination or a round kick evaluation, cannot be measured with them. This work proposes an alternative cadence-measurement system with less of the mentioned restrictions, without the need for distinct cadence-measurement apparatus attached to the pedal and shaft of the road bicycle.

Data Exchange Standards in Teleophthalmology: Current and Future Developments.

Background: Teleophthalmology services are considered capable of supporting screening, early diagnosis, and monitoring of leading causes of blindness on a global scale. Therefore, standards and best practices are needed to seamlessly exchange medical ocular images and related data among relevant stakeholders with maximum interoperability.

Objectives: This paper provides an overview of current standards in the field of store-and-forward teleophthalmology data exchange and further developments in this area.

Grit increases strongly in early childhood and is related to parental background.

Grit has been identified as a very important non-cognitive skill that is positively related to educational achievements and labor market success. Recently, it has also been found to be malleable through interventions in primary schools. Yet, little is still known about its development in early childhood and the influence of family background.

Targeted isolation of photoactive pigments from mushrooms yielded a highly potent new photosensitizer: 7,7'-biphyscion.

Pigments of fungi are a fertile ground of inspiration: they spread across various chemical backbones, absorption ranges, and bioactivities. However, basidiomycetes with strikingly colored fruiting bodies have never been explored as agents for photodynamic therapy (PDT), even though known photoactive compound classes (e.g.

Splashing of Large Helium Nanodroplets upon Surface Collisions.

In the present work we observe that helium nanodroplets colliding with surfaces can exhibit splashing in a way that is analogous to classical liquids. We use transmission electron microscopy and mass spectrometry to demonstrate that neutral and ionic dopants embedded in the droplets are efficiently backscattered in such events. High abundances of weakly bound He-tagged ions of both polarities indicate a gentle extraction mechanism of these ions from the droplets upon collision with a solid surface.

An analysis of the COVID-19 vaccination campaigns in France, Israel, Italy and Spain and their impact on health and economic outcomes.

Objectives: This paper presents an overview of the vaccination campaigns in France, Israel, Italy and Spain during the first eleven months from the first COVID-19 vaccine approval (Dec 2020 - Nov 2021). These four countries were chosen as they share similar socioeconomic, and epidemiological profiles and adopted similar vaccination strategies.

Methods: A rapid review of available primary data from each country was conducted.

The Implementation of National Dementia Plans: A Multiple-Case Study on Denmark, Germany, and Italy.

In a theory-driven, qualitative, multiple-case study, we examined the implementation of national dementia plans (NDPs) in Denmark, Germany, and Italy to determine how stakeholders involved in implementing the NDPs evaluate contextual factors in light of the World Health Organization's seven action areas of dementia-focused policy. To analyse the NDPs, we used a driver diagram of large-scale change and conducted both document analysis and semi-structured interviews, after which we performed three-way open coding to analyse the methods. The results show that the implementation of NDPs has increased awareness of dementia in all three countries by positioning the disease as a national public health concern.

The stock market as a casino: Associations between stock market trading frequency and problem gambling.

Background And Aims: Personal investors decrease their stock market investment returns by trading frequently, which the behavioral finance literature has primarily explained via investors' overconfidence and low levels of financial literacy. This study investigates whether problem gambling can help account for frequent trading in a sample of active gambler/investors, as suggestive of frequent trading being in part driven by a behavioral addiction to gambling-like activities.

Methods: A retrospective cross-sectional study of 795 US-based participants, who reported both being active gamblers and holding stock market investments.

Guiding Molecularly Imprinted Polymer Design by Pharmacophore Modeling.

Molecularly imprinted polymers (MIP) combine the selectivity of immunoaffinity chromatography with the robustness of common solid-phase extraction in what is referred to as molecularly imprinted solid-phase extraction (MISPE). This contribution shows how MIP design may be guided by pharmacophore modeling for the example of citrinin, which is an emerging mycotoxin from cereals. The obtained pharmacophore model allowed searching public databases for a set of citrinin-mimicking molecular surrogates.

On the effect of the inlet configuration for anaerobic digester mixing.

Sludge recirculation mixing in anaerobic digesters is essential for the stable operation of the digestion process. While often neglected, the configuration of the sludge inlet has a substantial influence on the efficiency of the mixing process. The fluid is either injected directly into the enclosed fluid domain or splashes onto the free surface of the slurry flow.

Triple helices' perspectives on the availability of human and financial capital for biopharmaceutical innovation in select Central European ecosystems.

Here, we examine the perspective of triple helix actors (i.e., those in academia, government, and industry) related to the availability of human and financial capital in select Central European ecosystems.

SF: Stabilizing Transient Ions in Helium Nanodroplets.

There are myriad ions that are deemed too short-lived to be experimentally accessible. One of them is SF. It has never been observed, although not for lack of trying.

Healthwashing in high-sugar food advertising: the effect of prior information on healthwashing perceptions in Austria.

In the context of exceeding levels of sugar consumption, some food companies advertise high-sugar products using inappropriate and misleading health claims (i.e. healthwashing).

How threat perceptions relate to learning and conspiracy beliefs about COVID-19: Evidence from a panel study.

According to appraisal theory, individuals cope with perceived threats in different ways. If engaging in problem-focused coping, for example, they may seek information useful for eliminating the root cause of the threat. However, during crises such as the COVID-19 pandemic, people tend to navigate complex information environments marked by high levels of uncertainty.