9,955 results match your criteria: "Mali; Neurology Department of the Gabriel Toure Teaching Hospital[Affiliation]"

A new genus and two new species of Cossidae (Lepidoptera: Cossoidea) from India and Pakistan.

Zootaxa

November 2024

Zoological Survey of India; M-Block New Alipore; Kolkata 700 053; West Bengal; India.

Aroriella gen. nov., which includes two new species, A.

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Introduction: Malnutrition contributes to 45% of all childhood deaths globally, but these modelled estimates lack direct measurements in countries with high malnutrition and under-5 mortality rates. We investigated malnutrition's role in infant and child deaths in the Child Health and Mortality Prevention Surveillance (CHAMPS) network.

Methods: We analysed CHAMPS data from seven sites (Bangladesh, Ethiopia, Kenya, Mali, Mozambique, Sierra Leone and South Africa) collected between 2016 and 2023.

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Introduction: Since 2012, the World Health Organization (WHO) and UNICEF have recommended integrated Community Case Management (iCCM) of childhood illnesses as an intervention delivered by community health workers (CHWs) in areas with limited access to health facilities to increase access to lifesaving interventions for children younger than 5 years with malaria, pneumonia, or diarrhea. In recent years, the importance of institutionalizing iCCM and community health more broadly within national health systems has become increasingly recognized.

Methods: This qualitative study sought to identify and describe processes of iCCM institutionalization from the perspectives of health system actors.

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Mitogen-activated protein (MAP) kinase signalling pathway VmMkh1-VmMkk1-VmSpm1 regulates cell wall integrity in Valsamali.

Microb Pathog

January 2025

Shandong Research Center for Forestry Harmful Biological Control Engineering and Technology, College of Plant Protection, Shandong Agricultural University, Tai'an, 271018, Shandong, China. Electronic address:

Article Synopsis
  • Apple Valsa canker disease, caused by Valsa mali, threatens apple tree growth, and this study explores the role of specific MAPK signaling pathway components (VmMkh1, VmMkk1, and VmSpm1) in this process.
  • Deletion of these components slows growth, reduces the production and germination of conidia, and hampers survival under stress conditions (like high salinity and cell wall disruptors).
  • The research indicates that these components are crucial in regulating various aspects like growth, stress response, and pathogenicity associated with Valsa mali.
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Background And Objectives: Developmental and epileptic encephalopathies (DEEs) are a group of neurological disorders characterized by early-onset seizures that are often resistant to treatment, by electroencephalographic abnormalities, and by developmental delay or regression. Their genetic basis remains largely unelucidated, especially in sub-Saharan Africa (SSA). We investigated the genetic bases of DEE in three Malian families.

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A Comprehensive Review on Immunoregulatory Effects of Phytochemicals.

Curr Drug Discov Technol

December 2024

Department of Mathematics and Natural Sciences, College of Sciences and Human Studies, Prince Mohammad Bin Fahd University, Al Khobar, Kingdom of Saudi Arabia.

An efficient immune system in the host body plays a crucial role in the preservation of normal biological and immune reactions and processes, as well as the intrinsic environment. This is because the immune system is responsible for fighting off foreign invaders. A healthy immune system strengthens the body's defense against infections, illnesses, and other unwelcome pathogens, thereby reducing the risk of allergic reactions and autoimmune diseases.

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Mali is a country where little information is known about the circulation of avian influenza viruses (AIVs) in poultry. Implementing risk-based surveillance strategies would allow early detection and rapid control of AIVs outbreaks in the country. In this study, we implemented a multi-criteria decision analysis (MCDA) method coupled with geographic information systems (GIS) to identify risk areas for AIVs occurrence in domestic poultry in Mali.

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Mesalamine (MES) is a preferred therapeutic agent for managing various colon disorders, including inflammatory bowel diseases (IBD). However, conventional oral dosage forms of MES face significant limitations, which reduce their effectiveness in managing these conditions. To overcome these challenges, advanced dosage forms of MES are essential.

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The impact of HIV antiretroviral therapy on gut microbiota: the need for well-designed longitudinal studies.

J Infect Dev Ctries

October 2024

University Clinical Research Center (UCRC), University of Sciences, Techniques and Technologies of Bamako (USTTB), Bamako, Mali.

Introduction: Human immunodeficiency virus (HIV) infection remains a major public health concern despite a significant decline in HIV-related mortality and morbidity. These significant advances are linked mostly to effective antiretroviral therapy (ART). However, these treatments are not without consequences on other microorganisms in our body, especially when they must be used for life.

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To mitigate the impact of traditional chemical pesticides on environment, and achieve sustainable crop protection, 24 eco-friendly rosin-based sulfonamide derivatives were synthesized and developed. The in vitro activity assessment showed that compound 4X (Co. 4X) exhibited excellent fungicidal activity against V.

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Cell-free and cell-based antidiabetic effects and chemical characterization of rice bran from Thai cultivars.

Food Res Int

November 2024

REQUIMTE/LAQV, Laboratório de Farmacognosia, Departamento de Química, Faculdade de Farmácia, Universidade do Porto, R. Jorge Viterbo Ferreira, n° 228, 4050-313 Porto, Portugal. Electronic address:

Rice bran is a valuable by-product of rice milling, prized for its nutritional value and health benefits. This study investigates the antidiabetic properties of rice bran from fifteen commercially available Thai rice cultivars (six brown, four red and five purple). Bran samples were initially screened on their antioxidant potential and ability to inhibit α-glucosidase, as well as on γ-oryzanol levels, total phenolic and total flavonoid contents.

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Cognitive testing in 19 countries to refine WHO's Sexual Health Assessment of Practices and Experiences.

Bull World Health Organ

December 2024

Department of Sexual and Reproductive Health and Research, World Health Organization, Avenue Appia 20, 1211 Geneva 27, Switzerland.

Article Synopsis
  • The study aimed to improve a standard questionnaire on sexual practices and health outcomes for better understanding across different cultures by assessing participants' willingness to answer and how they interpreted the questions.
  • Researchers conducted 645 cognitive interviews in 19 countries between March 2022 and March 2023, gathering diverse perspectives to identify misunderstandings and barriers in responding to the questionnaire.
  • The results showed that most participants were open to discussing sensitive topics, leading to necessary revisions in the questionnaire to enhance clarity and cultural relevance, ultimately making it more accessible to a global audience.
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The development of low-cost, eco-friendly, and earth-friendly electrode materials for energy storage and conversion applications is a highly desirable but challenging task for strengthening the existing renewable energy systems. As part of this study, orange peel extract was utilized to synthesize a magnesium oxide-silicon dioxide hybrid substrate system (MgO-SiO) for coating cobalt oxide nanostructures (CoO) hydrothermal methods. A variety of MgO-SiO compositions were used to produce CoO nanostructures.

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Background: Child growth influences future health and learning. School readiness refers to a child's ability to meet developmental expectations at school entry. The association of early growth rate and patterns with school readiness remains unknown.

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Article Synopsis
  • * A qualitative study involving 35 patients with non-communicable diseases revealed that facilitators for using healthcare services included free medicines, accessibility, and positive interactions with providers, while barriers included insufficient services, high costs, and lack of information.
  • * The study concludes that improving the utilization of NCD services can be achieved by enhancing patient knowledge, motivation, and addressing misconceptions, along with strengthening healthcare accessibility and provider-patient communication.
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Design, Synthesis, and Antifungal Evaluation of Novel Cuminic Acid Derivatives as Potential Laccase Inhibitors.

J Agric Food Chem

December 2024

Jiangsu Co-Innovation Center of Efficient Processing and Utilization of Forest Resources, Jiangsu Provincial Key Lab for the Chemistry and Utilization of Agro-Forest Biomass, Jiangsu Key Lab of Biomass-Based Green Fuels and Chemicals, College of Chemical Engineering, Nanjing Forestry University, Nanjing 210037, China.

In search of novel natural product-based fungicides, 49 cuminic acid derivatives were designed, synthesized, and screened for their in vitro antifungal effects toward seven phytopathogenic fungi and oomycetes. Consequently, several derivatives exhibited strong antifungal activities toward , , and . Among them, compound exhibited the most potent antifungal activity toward (EC = 0.

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The significance of exopolysaccharides (EPS) in various applications has garnered increasing attention. In this study, two bacteria, Liquorilactobacillus hordei SK6 and Liquorilactobacillus mali SK26, isolated from traditional water kefir grains, produced 8.89 g/L and 7.

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Apple leaf spot, caused by Alternaria alternata f. sp mali (ALT), poses a substantial threat to the global apple (Malus × domestica Borkh.) industry.

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Article Synopsis
  • Plant pathogenic fungi threaten crop yield and food security, leading to a study on camphor-thiazole derivatives' antifungal activity against six specific fungi.
  • Most of the synthesized derivatives showed significant antifungal effects, with compounds C5, C10, and C17 having noteworthy activity against R. solani, outperforming the control drug boscalid.
  • Preliminary studies indicate that compound C5 alters fungal morphology and increases reactive oxygen species production, highlighting its potential as a lead antifungal agent for further research.
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Introduction: The objective is to evaluate factors associated with Covid 19 vaccine hesitancy in Mali.

Methods: A cross-sectional survey was conducted among the general population aged 18 and over, in rural and urban areas in Mali. Two-stage sampling was used.

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Article Synopsis
  • The study aimed to assess mental disorders and addictive behaviors among gold miners treated at a hospital in Burkina Faso over a decade.
  • It involved 174 male patients, mostly young and single, with high rates of acute psychotic disorders and substance use, particularly tobacco, cannabis, and alcohol.
  • The findings indicate that mental health issues among gold miners are a significant public health concern in Burkina Faso, especially with the increase in gold mining activities.
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