79 results match your criteria: "Malaysian Institute of Chemical and Bioengineering Technology[Affiliation]"

Introduction: Burkholderia thailandensis E264 is a non-pathogenic soil bacterium that produces rhamnolipids (RLs), which are utilised in various fields. Although studies have illustrated changes in RLs congeners in response to environmental factors, studies on the influence of temperature on the RLs congeners produced by B. thailandensis E264 are scarce.

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Introduction: Inhalation drug delivery can deliver high doses of chemotherapeutic drugs to the lung tumor. This study evaluates the efficacy and the mechanistic pathways of nebulized Cur NPs at various sizes to treat multidrug resistant lung cancer.

Methods And Results: Cur-NPs (30 nm and 200 nm) were nebulized separately onto the multidrug-resistant lung cancer cells (H69AR).

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Article Synopsis
  • - Sulphur dioxide (SO₂) is a harmful pollutant primarily produced from burning fossil fuels and processing certain ores, with various methods for its removal, among which wet flue gas desulphurisation (FGD) is most common but associated with significant challenges like wastewater management and high water usage.
  • - An alternative approach explored in this study involves dry FGD using fibrous mesoporous silica (KCC-1) modified with choline chloride-based deep eutectic solvents, particularly choline chloride-glycerol, enhancing SO₂ adsorption capacity significantly compared to unmodified versions.
  • - Results indicate that the modified KCC-1 shows better performance in SO₂ removal due to its high porosity and the ability
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Background: Kenaf seeds are a rich source of protein; however, finding the best extraction method is crucial to obtaining high-quality protein from these underutilized seeds. This research devised an optimized extraction process for best recovery of kenaf seeds protein using response surface methodology. The key parameters affecting the yield and protein content were optimized, including extraction pH (2-11), seed:water ratio (5:1-50:1), temperature (30-90 °C), and duration (20-360 min).

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Multifaceted Impact of Lipid Extraction on the Characteristics of Polymer-Based Sewage Sludge towards Sustainable Sludge Management.

Polymers (Basel)

September 2024

Green Chemistry and Sustainability Cluster, Malaysian Institute of Chemical and BioEngineering Technology, Universiti Kuala Lumpur, Alor Gajah 78000, Melaka, Malaysia.

Dewatered sludge (DS) is a sewage sludge with a unique property due to extracellular polymeric substances (EPSs) and polymer flocculants. These components form a stable 3D polymer network to increase dewatering efficiency, leaving behind valuable materials such as lipids. This article explored the influences of DS particle size on lipid yield and the effects of extraction on the chemical, morphological, and thermal properties of the residual dewatered sludge (RDS).

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Synergistic Reinforcement with SEBS-g-MAH for Enhanced Thermal Stability and Processability in GO/rGO-Filled PC/ABS Composites.

Polymers (Basel)

September 2024

Green Chemistry and Sustainability Cluster, Branch Campus, Malaysian Institute of Chemical and Bioengineering Technology, University Kuala Lumpur, Alor Gajah 78000, Melaka, Malaysia.

The integration of compatibilisers with thermoplastics has revolutionised the field of polymer composites, enhancing their mechanical, thermal, and rheological properties. This study investigates the synergistic effects of incorporating SEBS-g-MAH on the mechanical, thermal, and rheological properties of polycarbonate/acrylonitrile-butadiene-styrene/graphene oxide (PC/ABS/GO) (PAGO) and the properties of polycarbonate/acrylonitrile-butadiene-styrene/graphene oxide (PC/ABS/rGO) (PArGO) composites through the melt blending method. The synergistic effects on thermal stability and processability were analysed by using thermogravimetry (TGA), melt flow index (MFI), and Fourier-transform infrared spectroscopy (FTIR).

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The potential of Hylocereus polyrhizus peel (HPP) as a new eco-friendly reinforcement for thermoplastic sago starch/agar composite (TPSS/agar) was investigated. The integration of HPP into TPSS/agar composite aimed to enhance its mechanical and thermal characteristics. The study employed Fourier transform-infrared spectroscopy (FT-IR), Scanning electron microscopy (SEM), Thermogravimetric analysis (TGA), and Differential Scanning Calorimetry (DSC), as well as mechanical, physical properties and soil burial testing to analyse the composites.

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Article Synopsis
  • Research on the speciation of sulfur and hydrogen molecules during thermophilic dark fermentation has shown how these gases interact with zeolites as effective adsorbents.
  • The study revealed that Zeolite Socony Mobil - 5 has an optimal adsorption capacity for hydrogen sulfide at 25 °C, with a maximum value of 0.00890 mg/g, indicating temperature plays a crucial role in its effectiveness.
  • The findings suggest that the removal of hydrogen sulfide not only improves the quality of biohydrogen produced but also follows specific kinetic and thermodynamic behaviors modeled using the Avrami kinetic and Temkin isotherm models.
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In an era where synthetic supplements have raised concerns regarding their effects on human health, has emerged as a natural alternative rich in polyphenolic compounds with potent therapeutic properties. Various studies on focusing on the analysis and validation of its pharmacological and nutritional properties are emerging. This paper summarizes present data and information on the phytochemical, nutritional values, therapeutic potential, as well as the toxicity profile of .

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Methicillin-resistant Staphylococcus aureus (MRSA) infections have become one of the most threatening multidrug-resistant pathogens. Thus, an ongoing search for anti-MRSA compounds remains an urgent need to effectively treating MRSA infections. Phomopsidione, a novel antibiotic isolated from Diaporthe fraxini, has previously demonstrated potent anti-candidal activity.

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Since ancient times, essential oils (EOs) derived from aromatic plants have played a significant role in promoting human health. EOs are widely used in biomedical applications due to their medicinal properties. EOs and their constituents have been extensively studied for treating various health-related disorders, including cancer.

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Synthesis and Characterization of a Novel Nanosized Polyaniline.

Polymers (Basel)

November 2023

Green Chemistry and Sustainability Cluster, Branch Campus, Malaysian Institute of Chemical and Bio-Engineering Technology, Universiti Kuala Lumpur (UniKL), Taboh Naning, Alor Gajah 78000, Melaka, Malaysia.

Polyaniline (PANI) is a conductive polymer easily converted into a conducting state. However, its limited mechanical properties have generated interest in fabricating PANI composites with other polymeric materials. In this study, a PANI-prevulcanized latex composite film was synthesized and fabricated in two phases following chronological steps.

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Environmental impact assessment of glucose production from paddy milling waste, known as empty and partially filled paddy grain (EPFG) in Malaysia, was performed using life cycle assessment (LCA). Three scenarios were conducted based on system expansion of the process. The LCA was conducted using ReCiPe methodology at midpoint and endpoint levels.

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Research Background: The presence of on raw food products raises the concern of yersiniosis as most of the berries are consumed raw. This is a challenging issue from the food safety aspect since it could increase the occurrence of foodborne diseases among humans. Thus, it is crucial to implement an effective sanitation before the packaging.

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Vancomycin is the last resort antibiotic for the treatment of severe bacterial keratitis. Its clinical application is limited due to its hydrophilicity and high molecular weight. To overcome this, this study aims to develop nanoparticles-laden contact lens for controlled ocular delivery of vancomycin.

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Plastics are still the most popular food packaging material and many of them end up in the environment for a long period. Due to packaging material's inability to inhibit microbial growth, beef often contains microorganisms that affect its aroma, colour and texture. Cinnamic acid is categorized as generally recognised as safe and is permitted for use in food.

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The implementation of inorganic adsorbents for the removal of heavy metals from industrial effluents generates secondary waste. Therefore, scientists and environmentalists are looking for environmentally friendly adsorbents isolated from biobased materials for the efficient removal of heavy metals from industrial effluents. This study aimed to fabricate and characterize an environmentally friendly composite bio-sorbent as an initiative toward greener environmental remediation technology.

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Magnetic chitosan/cellulose nanofiber-Fe(III) [M-Ch/CNF-Fe(III)] composites were isolated for the elimination of Cr(VI), Cu(II), and Pb(II) from aqueous solution. Various analytical methods, such as field emission scanning electron microscopy (FE-SEM), transmission electron microscopy (TEM), Fourier-transform infrared spectroscopy (FT-IR), X-ray diffraction analysis (XRD), and thermogravimetric analysis (TGA) were employed to determine the morphological, physicochemical, and thermal properties of the isolated M-Ch/CNF-Fe(III) composites. It was found that the M-Ch/CNF-Fe(III) composites were porous materials, and they have the potential to be implemented as an adsorbent for heavy metals removal.

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2-Octylcyclopentanone Inhibits Beta Lactam Resistant Diabetic Wound Pathogens.

Trop Life Sci Res

March 2023

Department of Fundamental and Applied Sciences, Institute of Sustainable Building, Centre for Biofuel and Biochemical Research, Universiti Teknologi PETRONAS, 32610 Seri Iskandar, Perak, Malaysia.

Microbial infection is a frequent complication of diabetic foot ulcers, with up to 82% of ulcers being infected at the initial stage of diabetes. Furthermore, the emergence of beta lactam resistant pathogens managed to eliminate the use of beta lactam antibiotics as a chemotherapeutic alternative. This further increases the amputation and mortality rate.

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Crosslinked polyethylene (XLPE) nanocomposite has superior insulation performance due to its excellent dielectric, mechanical, and thermal properties. The incorporation of nano-sized fillers drastically improved these properties in XLPE matrix due to the reinforcing effect of interfacial region between the XLPE-nanofillers. Good interfacial strength can be further improved by introducing a hybrid system nanofiller as a result of synergistic interaction between the nanofiller relative to a single filler system.

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Thermoplastic starch is a material that has the potential to be environmentally friendly and biodegradable. However, it has certain drawbacks concerning its mechanical performance and is sensitive to the presence of moisture. The current study assessed agar-containing thermoplastic sago starch (TPSS) properties at various loadings.

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Thermo-Responsive Polymer-siRNA Conjugates Enabling Artificial Control of Gene Silencing around Body Temperature.

Pharm Res

January 2023

Laboratory for Chemistry and Life Science, Institute of Innovative Research, Tokyo Institute of Technology, 4259 Nagatsuta-cho, Midori-ku, Yokohama, Kanagawa, 226-8503, Japan.

Purpose: Controlling small interfering RNA (siRNA) activity by external stimuli is useful to exert a selective therapeutic effect at the target site. This study aims to develop a technology to control siRNA activity in a thermo-responsive manner, which can be utilized even at temperatures close to body temperature.

Methods: siRNA was conjugated with a thermo-responsive copolymer that was synthesized by copolymerization of N-isopropylacrylamide (NIPAAm) and hydrophilic N,N-dimethylacrylamide (DMAA) to permit thermally controlled interaction between siRNA and an intracellular gene silencing-related protein by utilizing the coil-to-globule phase transition of the copolymer.

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Spray dryer had long been used to dry liquid materials and produce dry crystalline products. However, the drying of the bittern to produce quality salt crystals has not been widely published. Therefore, the purpose of this study was to examine the effect of drying conditions of the bittern using a spray dryer to produce salt with a high natrium chloride (NaCl) content.

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In this study, thermoplastic cassava starch-palm wax blends, reinforced with the treated fiber (TPCS/ PW/ CCF) were successfully developed. The TPCS were priorly modified with palm wax to enhance the properties of the matrix. The aim of this study was to investigate the influence of alkali treatments on the TPCS/PW/CCF biocomposite.

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