2 results match your criteria: "Malaysia. Electronic address: leemt@ucsiuniversity.edu.my.[Affiliation]"

Ameliorative effect of α-tocopherol and tocotrienol-rich palm oil extract on menopause-associated mood disorder in ovariectomized mice.

Biochem Biophys Res Commun

November 2024

Faculty of Pharmaceutical Sciences, UCSI University, Kuala Lumpur, 56000, Malaysia; Office of Postgraduate Studies, UCSI University, Kuala Lumpur, 56000, Malaysia; UCSI Wellbeing Research Centre, UCSI University, Kuala Lumpur, 56000, Malaysia. Electronic address:

Article Synopsis
  • * A study evaluated the effects of vitamin E compounds—α-tocopherol and tocotrienol-rich palm oil extract—on anxiety and depressive behaviors in mice with estrogen deficiency, finding that these compounds had positive effects on mood-related behaviors.
  • * The results indicated that both supplements reduced stress hormone levels and improved symptoms, suggesting they could be a promising new treatment option for menopause-related mood disorders, potentially influencing the hypothalamic-pituitary-adrenal (HPA) axis.
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Clinacanthus nutans aqueous leaves extract exerts anti-allergic activity in preclinical anaphylactic models via alternative IgG pathway.

J Ethnopharmacol

March 2023

Department of Biomedical Science, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Serdang, 43400, Malaysia. Electronic address:

Ethnopharmacological Relevance: Allergy is mediated by the crosslinking of immunoglobulins (Ig) -E or -G to their respective receptors, which degranulates mast cells, macrophages, basophils, or neutrophils, releasing allergy-causing mediators. The removal of these mediators such as histamine, platelet-activating factor (PAF) and interleukins (ILs) released by effector cells will alleviate allergy. Clinacanthus nutans (C.

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