Epidemiology of Post-craniotomy Hypertension and Its Association With Adverse Outcome(s): A Systematic Review and Meta-analysis.

After intracranial surgery, sympathetic overdrive and increased blood catecholamine levels can contribute to postoperative hypertension, a significant clinical problem. The objective of this review was to summarize, quantify, and assess the epidemiological perspective of post-craniotomy hypertension and its association with adverse outcomes. This PROSPERO-registered systematic review was conducted following PRISMA guidelines.

Upregulated PCAT-1 predicts poor prognosis and reduced immune cell infiltration in head and neck squamous cell carcinoma through the miR-145-5p / FSCN-1 axis.

Background: LncRNA PCAT-1 is known to promote cancer proliferation, invasion, and metastasis. However, its significance in HNSCC is not fully understood. This research investigates how the PCAT-1 / miR-145-5p / FSCN-1 axis promote HNSCC.

Eustress responses of Musa acuminata cv. red banana using LED spectra.

This study examined the impacts of different LED spectra on the growth of in vitro cultures of Musa acuminata cv. red banana and their biochemical profile, including the antioxidant enzymes catalase and ascorbate peroxidase, photosynthetic pigment and accumulation of total carbohydrate content. The far-red LEDs significantly increase shoot elongation (10.

Pharmacy students' perspective on remote flipped classrooms in Malaysia: a qualitative study.

Purpose: This study aimed to explore pharmacy students' perceptions of remote flipped classrooms in Malaysia, focusing on their learning experiences and identifying areas for potential improvement to inform future educational strategies.

Methods: A qualitative approach was employed, utilizing inductive thematic analysis. Twenty Bachelor of Pharmacy students (18 women, 2 men; age range, 19-24 years) from Monash University participated in 8 focus group discussions over 2 rounds during the coronavirus disease 2019 pandemic (2020-2021).

Fungal infections and control strategies in cultured marine finfish: a minireview.

Marine fish farming served as a sustainable alternative to capture fisheries. However, it faced challenges such as disease management, water quality maintenance, and minimizing environmental impacts. Among these challenges, fungal infections are particularly concerning.

Comparing the effects of computerized versus manual methods of identifying point-specific acupuncture as an adjunct to physiotherapy in the management of knee osteoarthritis: A randomized controlled trial protocol.

Background: Knee osteoarthritis (KOA) is a prevalent condition causing significant pain and functional impairment. Acupuncture has shown promise as an adjunctive therapy, but conventional manual selection of acupoints lacks standardization. The Acugraph system provides a computerized method for identifying acupoints, potentially enhancing treatment precision.

What makes a city breastfeeding friendly? A qualitative analysis of interviews with breastfeeding women from Europe and Asia.

Background: The warm chain of support is the continuous enabling environment from the mother's first contact with healthcare professionals during early pregnancy, birth and immediate post-partum period, her transition from healthcare facility to home, through to work and the community at large. A breastfeeding-friendly city should be able to support a breastfeeding journey across the warm chain.

Objective: To determine breastfeeding women's perspective of an ideal breastfeeding-friendly city.

Phytochemical Profiling and Biological Activities of Nigella sativa Vinegar Extract: An Insight Into Hypoglycemic Potential Using In Vivo and In Silico Studies.

The current study was conducted to characterize the vinegar extract of Nigella sativa and evaluate its biological activities using in vitro and in vivo studies. The N. sativa extract (NSE) was prepared by macerating seeds in a mixture of water and synthetic vinegar (1:10).

ATXN2 polyglutamine intermediate repeats length expansions in Malaysian patients with amyotrophic lateral sclerosis (ALS).

Intermediate CAG repeats from 29 to 33 in the ATXN2 gene contributes to the risk of amyotrophic lateral sclerosis (ALS) in European and Asian populations. In this study, 148 ALS patients of multiethnic descent: Chinese (56.1%), Malay (24.

Functional alignment is a feasible alignment strategy in robotic assisted total knee arthroplasty for knee osteoarthritis with extra-articular deformity - A case series.

Introduction: Extraarticular deformity (EAD) with knee arthritis is a complex condition involving tri-planar bone deformity with pathological malalignment and chronic soft tissue contracture or laxity in the knee joint. Intraarticular correction by TKA, which was previously performed with conventional manual jig by mechanical alignment technique, had its limits and difficulties especially extensive soft tissue release and risk of jeopardizing the collateral ligaments. Robotic technology allows for reproducible and precise execution of surgical plan and allows adjustment to various new personalised alignment philosophy including functional alignment (FA).

is enriched in invasive biofilms in colorectal cancer.

is an oral bacterium known to colonize colorectal tumors, where it is thought to play an important role in cancer progression. Recent advances in sequencing and phenotyping of have revealed important differences at the subspecies level, but whether these differences impact the overall tumor ecology, and tumorigenesis itself, remain poorly understood. In this study, we sought to characterize in the tumor microbiome of a cohort of individuals with CRC through a combination of molecular, spatial, and microbiologic analyses.

Identification of Sensory Drivers of Liking of Plant-Based Milk Using a Novel Palm Kernel Milk-The Effect of Reformulation and Flavors Addition Through CATA and PCA Analysis.

There is a growing demand for a plant-based diet (meat analogue/plant-based milk) due to an increase in awareness towards health issues, environmental sustainability, and animal ethical issues. The replacement of dairy has recently been one of the market efforts to fulfill such demand. Yet, challenges arise when consumers are reluctant to accept plant-based milk (PBM) due to the mismatch of organoleptic profile between PBM and the actual dairy.

Comparative Analyses and Phylogenetic Dependence in Traits and Trends of the Dipterocarpaceae.

The role of trait evolution in shaping the functional and ecological diversity of tropical forests remains poorly understood. Analyses of trait variation as a function of evolutionary history and environmental variables should reveal the drivers of species distributions, as well as generate insights valuable to conservation. Here, we focus on the Dipterocarpaceae, the key plant family underpinning the hyperdiversity of South-East Asian tropical forest canopies and of major conservation concern due to over-exploitation for timber, cultivation, and climate change.

Intralesional Bleomycin for Orbital Venolymphatic Malformation.

This retrospective case series evaluates the use of intralesional bleomycin injections in treating orbital venolymphatic malformations (OVLM). Three patients, a 7-year-old girl, a 37-year-old woman, and a 56-year-old man, presented with OVLM where the first two were recurrent cases with a history of failed sclerotherapy. All patients received multiple doses of intralesional bleomycin injections, resulting in significant reductions in lesion size, decreased proptosis, and pain relief.

Perspectives on Frailty Among Emergency Physicians: A Qualitative Descriptive Study.

Background The proportion of older people in the general population is rising. Accompanying this rise is an increased prevalence of frailty. Frailty is a syndrome of increased vulnerability to stressors due to decreased physiological reserve and is linked to increased health services use.

Trends in Cardiovascular Diseases and Costs Among Type 2 Diabetes Mellitus (T2DM) Patients in Malaysia: A Cohort Study of 240,611 Public Hospital Inpatients.

Background: Identifying trends of hospital admissions and costs for cardiovascular disease events (CVDEs) is crucial for public health intervention and the economic burden for future clinical improvements and better outcomes. This study aims to define the admission trends and cost of CVDE among type 2 diabetes mellitus (T2DM) patients in Malaysia between 2014 and 2020.  Methodology: An ecological study was conducted using hospital admission data taken from the Casemix database in public hospitals in Malaysia.

Asian Pacific Society of Cardiology Position Statement on the Use of Transcatheter Aortic Valve Implantation in the Management of Aortic Stenosis.

Transcatheter aortic valve implantation (TAVI) has been established as an effective treatment modality in patients with severe aortic stenosis (AS) and the uptake of TAVI is rapidly growing in the Asia-Pacific region. However, there exist a heterogeneity in the management of aortic stenosis and the use of TAVI among countries in the region. Reasons for these differences include anatomic variations, disparity in healthcare resources and infrastructure, and the lack of consensus on the optimal management of AS in the Asia-Pacific region.

Unlocking seismic slope stability for risk assessment.

Slope instability represents a substantial secondary hazard post-earthquake, leading to considerable socio-economic losses from the destruction of structures, infrastructure, and human lives. This study addresses the urgent need for precise evaluation of seismic slope stability, a subject that has gained significant attention in earthquake engineering over the past decade. A theoretical framework is proposed that utilizes an improved Sarma method, estimating seismic forces and safety factors based on limit equilibrium theory.

The complete plastid genome of DC. 1813 (Rutaceae) and its phylogenetic analysis.

The complete plastome size of DC. 1813 was 159,893 bp in length and has a typical quadripartite structure. The 87,148-bp-long large single-copy and the 18,763-bp-long small single-copy regions were separated by a pair of inverted repeats (each 26,991 bp).

Korth toxicity: Experimental findings and future prospects.

(Roxb.) Korth, locally known as kratom, is a traditional medicinal plant from Southeast Asia, with mitragynine as its principal alkaloid. Similar to other medicinal plants, kratom has side effects and toxicities, which have been documented in scientific studies and case reports.

Current antibiotics for leptospirosis: Are still effective?

Leptospirosis is a recurring zoonotic disease of global significance. Leptospirosis is curable, and antibiotics are available for its treatment. However, little is known about the effectiveness of the currently used antibiotics against different species, serovars, and strains.

A review of emerging techniques for pyrethroid residue detection in agricultural commodities.

Pyrethroid pesticides are essential for modern agriculture, helping to control pests and protect crops. However, due to growing concerns about their potential impact on human health and the environment, reliable detection methods are essential to ensure food safety. In this literature review, we explore the techniques used over the past decade to detect pyrethroid residues in agricultural products.

Enhancing sand screen performance with integrated slurry testing and CFD-DEM modelling.

Understanding the behavior of sand screens is crucial for optimizing sand control strategies and preventing wellbore failure, which can significantly impact reservoir management and production efficiency. This paper presents a comprehensive experimental and numerical modeling study on sand screen performance, aimed at providing insights prior to real-field applications. The study evaluated a 200-μm wire-wrapped screen (WWS) using slurry tests to determine the amount of sand retained, sand produced and retained permeability to assess screen efficiency.