Enhancing sand screen performance with integrated slurry testing and CFD-DEM modelling.

Understanding the behavior of sand screens is crucial for optimizing sand control strategies and preventing wellbore failure, which can significantly impact reservoir management and production efficiency. This paper presents a comprehensive experimental and numerical modeling study on sand screen performance, aimed at providing insights prior to real-field applications. The study evaluated a 200-μm wire-wrapped screen (WWS) using slurry tests to determine the amount of sand retained, sand produced and retained permeability to assess screen efficiency.

A two-stage deep learning-based hybrid model for daily wind speed forecasting.

Global adoption of wind energy continues to increase, while improving the efficiency of turbine settings requires reliable wind speed (WS) models. The latest models rely on artificial intelligence (AI) optimizations which constructs tests on a range of novel hybrid models to examine the reliability. Gradient Boosting (GB), Random Forest (RF), and Long Short-Term Memory (LSTM) are used in new combinations for data pre-processing.

Thyroid Hemiagenesis: An Incidental Discovery during Treatment for Papillary Thyroid Carcinoma.

Thyroid hemiagenesis (THA) is a rare congenital abnormality in which one of the thyroid lobes fails to develop normally. The prevalence rates range from 0.02% to 0.

Overweight, obesity, and cardiovascular disease in heterozygous familial hypercholesterolaemia: the EAS FH Studies Collaboration registry.

Background And Aims: Overweight and obesity are modifiable risk factors for atherosclerotic cardiovascular disease (ASCVD) in the general population, but their prevalence in individuals with heterozygous familial hypercholesterolaemia (HeFH) and whether they confer additional risk of ASCVD independent of LDL cholesterol (LDL-C) remains unclear.

Methods: Cross-sectional analysis was conducted in 35 540 patients with HeFH across 50 countries, in the EAS FH Studies Collaboration registry. Prevalence of World Health Organization-defined body mass index categories was investigated in adults (n = 29 265) and children/adolescents (n = 6275); and their association with prevalent ASCVD.

Efficacy and safety of repetitive transcranial magnetic stimulation with different frequencies on neuropathic orofacial pain: a systematic literature review and meta-analysis.

Repetitive transcranial magnetic stimulation (rTMS) is a non-invasive technique used to treat neuropathic orofacial pain (NOP). This study aimed to evaluate the efficacy and safety of rTMS in managing NOP and reducing health risks. A comprehensive literature search was conducted in various databases, including PubMed, Physiotherapy Evidence Database (PEDro), the Cochrane Library, Web of Science, Embase and Clinical Trials.

Impact of aeration on plant growth-promoting rhizobacteria assisted phytoremediation capability of arsenic in artificial wetland system.

The increasing demand for sustainable, robust, and cost-efficient arsenic (As) treatment techniques strengthens the implementation of new constructed wetland (CW) designs like aerated CWs in the agricultural sector. The aim was to assess and contrast the influence of various aeration rates on As elimination in subsurface flow CW utilizing plants for treating As-polluted sand. This study consisted of an experiment with 16 subsurface flow CW, operating at different As concentrations of 0, 5, 22, and 39 mg kg and aeration rates of 0, 0.

Enhanced Electrocatalytic Hydrogen Peroxide Production via a CuWO/WO Heterojunction with High Selectivity and Stability.

The electrocatalytic conversion of oxygen to hydrogen peroxide offers a promising pathway for sustainable energy production. However, the development of catalysts that are highly active, stable, and cost-effective for hydrogen peroxide synthesis remains a significant challenge. In this study, a novel polyacid-based metal-organic coordination compound (Cu-PW) was synthesized using a hydrothermal approach.

Alginate coated mesoporous silica nanoparticles as oral delivery carrier of curcumin and quercetin to colon cancer: preparation, optimization, characterization, and anticancer activity.

The synergistic bioactive effect of polyphenols can enhance the development of functional foods to prevent chronic diseases such as cancer. Curcumin and quercetin have been shown to possess anticancer properties. The combination of curcumin and quercetin has been shown to provide synergistic effects against cancer cell proliferation.

Prevalence and symptoms of Long Covid-19 in the workplace.

Background: The symptoms of Long coronavirus disease 2019 (Covid-19) are heterogeneous, creating uncertainty for employers regarding the diagnosis. The prevalence of Long Covid-19 in the workforce is also unknown. Furthermore, workers affected by Long Covid-19 encounter considerable difficulties in ensuring work safety and returning to their jobs due to this condition.

Effects of high-intensity training on jumping performance among athletes: a systematic review with meta-analysis.

This review aims to conduct a meta-analysis of the impact of high-intensity training (HIT) on athlete jumping performance. As of May 2024, we conducted a comprehensive search on PubMed, Web of Science, SCOPUS, and EBSCOhost databases in accordance with the PRISMA guidelines. Use the PEDro scale to evaluate the methodological quality of the included study.

Targeting the ERK1/2 and p38 MAPK pathways attenuates Golgi tethering factor golgin-97 depletion-induced cancer progression in breast cancer.

Background: The Golgi apparatus is widely considered a secretory center and a hub for different signaling pathways. Abnormalities in Golgi dynamics can perturb the tumor microenvironment and influence cell migration. Therefore, unraveling the regulatory network of the Golgi and searching for pharmacological targets would facilitate the development of novel anticancer therapies.

Advocacy in Action: International Patient Group Improves Hereditary Angioedema Diagnosis and Care Across the Asia-Pacific.

This study demonstrates that patient advocacy groups significantly enhance medication availability and improve diagnosis of hereditary angioedema (HAE), particularly in emerging economies within the Asia-Pacific region. This study supports integrating patient advocacy group involvement into management guidelines, emphasising their role in improving access to diagnostics and treatment for HAE.

Investigating the efficacy of gellan gum hydrogel films infused with Acacia stingless bee honey in wound healing.

Effective wound healing requires biocompatible and functional wound dressings. This study explores the synergistic potential of gellan gum (GG), known for its exceptional gel-forming abilities, and acacia stingless bee honey (SBH), for its potent antioxidant properties, in developing advanced wound care solutions. GG hydrogel films incorporated with varying concentrations of SBH (v/v) at 10 % (GGSBH10), 15 % (GGSBH15), and 20 % (GGSBH20) were characterized.

Asian Thoracic Oncology Research Group expert consensus statement on the peri-operative management of non-small cell lung cancer.

The peri-operative management of non-small cell lung cancer (NSCLC) in earlier stage disease has seen significant advances in recent years with the incorporation of immune checkpoint inhibitors and targeted therapy. However, many unanswered questions and challenges remain, including the application of clinical trial data to routine clinical practice. Recognising the unique demographic profile of Asian patients with NSCLC and heterogeneous healthcare systems, the Asian Thoracic Oncology Research Group (ATORG) convened a consensus meeting in Singapore on 26 April 2024 to discuss relevant issues spanning diagnostic testing to post-neoadjuvant treatment considerations and future directions.

Carbohydrate-based co-encapsulation of spice oleoresin blends: Impact on flavor release profiles, storage stability, and sensory acceptance.

The study highlights the impact of different carbohydrate-based wall materials on the encapsulation and release of flavors and physicochemical characteristics of spray-dried oleoresin blends. The inlet temperature and the wall material type significantly affected the spray drying yield, and Hi-Cap 100, at 150 °C, produced the highest yield. All the wall materials had high water solubility, and Hi-Cap 100 reported the best wettability.

Role of antioxidative stress activity of Fucoxanthin nanoparticle as hepatoprotective in diabetic rats.

This study attempts to prove that the antioxidant effect of fucoxanthin nanoparticles can prevent streptozotocin-induced rat liver damage. Fucoxanthin nanoparticles are synthesized using the high-energy ball milling method. Dynamic Light Scattering (DLS) was then used to describe the sizes of the fucoxanthin nanoparticles.

Colors of the mind: a meta-analysis of creative arts therapy as an approach for post-traumatic stress disorder intervention.

Background: In clinical practice, creative arts therapy is frequently utilized for the treatment of traumatized adults, with reports of favorable outcomes. However, the effectiveness of this intervention in post-traumatic stress disorder (PTSD) treatment has not yet been definitively established through meta-analysis. In this meta-analysis, we aim to assess the effectiveness of creative arts therapy in the management of PTSD.

Intelligent skin disease prediction system using transfer learning and explainable artificial intelligence.

Skin diseases impact millions of people around the world and pose a severe risk to public health. These diseases have a wide range of effects on the skin's structure, functionality, and appearance. Identifying and predicting skin diseases are laborious processes that require a complete physical examination, a review of the patient's medical history, and proper laboratory diagnostic testing.

Emerging and re-emerging viral infections of the central nervous system in Australasia and beyond.

Viral infections of the central nervous system (CNS) have been emerging and re-emerging worldwide, and the Australasia region has not been spared. Enterovirus A71 and enterovirus D68, both human enteroviruses, are likely to replace the soon-to-be eradicated poliovirus to cause global outbreaks associated with neurological disease. Although prevalent elsewhere, the newly emergent orthoflavivirus, Japanese encephalitis virus (genotype IV), caused human infections in Australia in 2021, and almost certainly will continue to do so because of spillovers from the natural animal host-vector life cycle endemic in the country.

Metal nanoparticles entrapment in chitosan-carbon black composite hydrogel towards sustainable environmental solutions.

A catalytic system has been developed, utilizing metal nanoparticles confined within a chitosan‑carbon black composite hydrogel (M-CH/CB), aimed at improving ease of use and recovery in catalytic processes. The M-CH/CBs were characterized by XPS, XRD, SEM, and EDX, the M-CH/CB system demonstrated exceptional catalytic activity in producing hydrogen gas (H) from water and methanol, and in reducing several hazardous materials including 2-nitrophenol (2-NP), 4-nitrophenol (4-NP), 2,6-dinitrophenol (2,6-DNP), acridine orange (ArO), methyl orange (MO), congo red (CR), methylene blue (MB), and potassium ferricyanide (PFC). Among the tested nanocatalysts, CH/CB showed the highest efficiency for H₂ production, while Fe-CH/CB excelled in contaminant reduction (7.

Insulin and myometrial contractility; Are there any links? A narrative review.

Contrary to the evidence supporting the role for insulin in stimulating uterine contraction, only a limited number of studies have highlighted the inhibitory effect of insulin on myometrial contractions in human and rodent. A hypothetical narrative review of the current literature was conducted, revealing the current literature and shows the potential inhibitory effects of insulin on myometrial contractility. These inhibitory mechanisms include activation of adenylyl cyclase signaling pathways, an increase in cAMP production, a decrease in Ca influx and cytosolic Ca, hyperpolarization of the cell membrane, and stimulation of NO synthesis.

STAT3-related lncRNAs in colorectal cancer progression; Special focus on immune cell's evasion.

Colorectal cancer (CRC) is globally ranked as the third leading cause of cancer-related deaths in both men and women. There is an urgent need for novel biomarkers to facilitate early diagnosis and enhance patient care, thereby improving treatment response and reducing mortality rates. Signal transducer and activator of transcription 3 (STAT3) is essential for controlling the anti-tumor immune response since it is a hub for several oncogenic signaling pathways.