Magnetic resonance imaging safety in Asia-Oceania: call for action.

Magnetic Resonance Imaging (MRI) safety is a critical concern in the Asia-Oceania region, as it is elsewhere in the world, due to the unique and complex MRI environment that demands attention. This call-for-action outlines ten critical steps to enhance MRI safety and promote a culture of responsibility and accountability in the Asia-Oceania region. Key focus areas include strengthening education and expertise, improving quality assurance, fostering collaboration, increasing public awareness, and establishing national safety boards.

Online interest in ADHD predicts ADHD medication prescriptions in Australia from 2004 to 2023: A time-series analysis revealing COVID-19-related acceleration.

Objective: Attention-deficit hyperactivity disorder (ADHD) medication prescriptions in Australia have grown sharply in recent years. We examined the association between online interest in ADHD and prescriptions.

Methods: Monthly Pharmaceutical Benefits Scheme (PBS) and Repatriation PBS (RPBS) Item Reports of ADHD prescriptions and Australian ADHD-related Google Trends (GT) data (2004-2023) were sourced.

Effect of music therapy on emotional resilience, well-being, and employability: a quantitative investigation of mediation and moderation.

This study explores the impact of music therapy on emotional resilience, well-being, and employability. Through an 8-week music therapy intervention involving 256 participants, the results demonstrated that music therapy significantly enhanced participants' emotional resilience, which in turn improved their well-being and employability. A significant positive correlation was found between emotional resilience, well-being, and employability, with well-being mediating the relationship between emotional resilience and employability.

Prevalence and associated factors of healthy aging among community-dwelling older adults in Lishui city, China: a cross-sectional study.

Background: Identifying the level of healthy aging and exploring its associated factors are prerequisites in the planning of effective measures among the elderly population. Thus, this study aimed to investigate the prevalence of healthy aging and determine its associated factors among community-dwelling older adults from mountain areas in Lishui, China.

Methods: A multicenter cross-sectional survey was conducted.

Highly sensitive split ring resonator-based sensor for quality monitoring of edible oils.

This research presents the design and analysis of a compact metamaterial (MTM)-based star-shaped split-ring resonator (SRR) enclosed in a square, constructed on a cost-effective substrate for liquid chemical sensing applications. The designed structure has dimensions of 10 × 10 mm and is optimized for detecting adulteration in edible oils. When the sample holder is filled with different percentages of oil samples, the resonance frequency of the MTM-based SRR sensor shift significantly.

Investigating the impact of Multiwalled Carbon Nanotubes exposure on enzymatic activities and histopathological variations in Swiss albino mice.

Present study was conducted to evaluate the detrimental impacts of exposure of Multi-walled Carbon Nanotubes (MWCNT-NP) on enzymatic activities and tissue structures in Swiss albino mice. The experimental groups of mice received MWCNT-NP for specific time period (seven or fourteen days). Two distinct doses of the MWCNT-NP solution were given orally: 0.

Diabetic foot ulcer in the Western Pacific Region: Current data on ulceration rates and microbial profiles, gaps and charting strategies.

The Western Pacific Region hosts the largest proportion of people with diabetes. Despite being a key diabetes-related complication, diabetic foot ulcer has been neglected in both prevention and treatment efforts. This narrative review highlights available data on the burden (either prevalence or incidence), as well as microbial profiles of diabetic foot ulcers in the Western Pacific Region, identifies data gaps, and discusses strategies to address these gaps.

Microencapsulation using a novel wall material prepared via Maillard reaction-derived mung bean protein-peach gum conjugates to enhance stability and functionality of chia seed oil.

This study investigated the potential of Maillard reaction products (MRPs) derived from mung bean protein isolate (MBPI) and peach gum (PG) conjugates as wall materials for microencapsulating chia seed oil (CSO). Four formulations (MMRP) were prepared using spray-drying and compared to a commercial sample (CMMRP). The MMRP formulation exhibited the highest encapsulation yield (91 %) and encapsulation efficiency (96 %), along with favorable physical properties, including a spherical shape and smooth surface.

Fabrication and applications of biofunctional collagen biomaterials in tissue engineering.

Collagen is extensively used in tissue engineering for various organ tissue regeneration due to the main component of human organ extracellular matrix (ECM) and their inherent nature bioactivity. Collagen various types naturally exist in different organ ECMs. Collagen fabricated with natural ECM mimics architecture, composition and mechanical properties for various organ tissue regeneration.

Ultrasonic collaborative pulse extraction of sugarcane polyphenol with good antiaging and α-glucosidase inhibitory activity.

Sugarcane, as one important and heavily planted industrial crop, is meaningful to develop its byproducts. In this paper, the ultrasonic collaborative pulse was beneficial for the yield improvement and good bioactivity protection. The sugarcane polyphenol extract (SPE) yield reached 2.

Alginate-based materials as adsorbent for sustainable water treatment.

With the encroaching issue of water pollution, the use of involved chemicals to remove pollutants from water is not only a risk of chemical contamination, a potential hazard to the environment and human health but also requires significant investment in managing and improving the chemicals. Therefore, alginate as one of the nanomaterial-adorned polysaccharides-based entity that usually extract from brown algae has been used as novel and more efficient catalysts in the removal of a variety of aqueous pollutants from wastewater, including ionic metals and organic/inorganic pollutants by using the adsorption techniques. Adsorption is a technique used in water treatment where non-polar or particles less soluble in water are stuck to the surface of the adsorbent and therefore purifying it.

Hypomethylating agents as emerging therapeutics for triple-negative breast cancer.

Triple-negative breast cancer (TNBC) is recognized as the most aggressive subtype of breast cancer. Epigenetic silencing, such as DNA methylation mediated by DNA methyltransferases (DNMTs) plays key roles in TNBC tumorigenesis. Hypomethylating agents (HMAs) such as azacitidine, decitabine, and guadecitabine are key inhibitors of DNMTs, and accumulating evidence has shown their immunogenicity properties.

Aspirin after completion of standard adjuvant therapy for colorectal cancer (ASCOLT): an international, multicentre, phase 3, randomised, double-blind, placebo-controlled trial.

Background: Aspirin is a simple, globally available medication that has been shown to reduce the incidence of colorectal cancer. We aimed to evaluate the safety and efficacy of aspirin in the secondary prevention of colorectal cancer.

Methods: This phase 3, randomised, double-blind, placebo-controlled trial was conducted at 66 centres across 11 countries and territories (ten in Asia-Pacific; one in the Middle East).

Engineering a wirelessly self-powered neural scaffold based on primary battery principle to accelerate nerve cell differentiation.

Electrical stimulation displayed tremendous potential in promoting nerve regeneration. However, the current electrical stimulation therapy required complex traversing wires and external power sources, which significantly limited its practical application. Herein, a self-powered nerve scaffold based on primary battery principle was gradient printed by laser additive manufacturing technique.

Private, non-profit, and plantation: Oil palm smallholders in management-assistance programs vary in socio-demographics, attitudes, and management practices.

Smallholder farmers produce over 40% of global palm oil, the world's most traded and controversial vegetable oil. Awareness of the effects of palm oil production on ecosystems and human communities has increased drastically in recent years, with ever louder calls for the private and public sector to develop programs to support sustainable cultivation by smallholder farmers. To effectively influence smallholder practices and ensure positive social outcomes, such schemes must consider the variety in perspectives of farmers and align with their priorities.

Impact of low-carbon economic policies on the corporate environmental responsibility model in China.

This study investigates the impact of low-carbon economic policies on Corporate Environmental Responsibility (CER) in Chinese A-share listed companies, with a particular focus on the role of financing constraints as a mediating factor. Despite a decrease in environmental pollution incidents in 2022, the economic and social impacts of such incidents remain significant, highlighting the need for stronger environmental governance. Building upon previous research, this study utilizes data from the Shanghai and Shenzhen stock exchanges (2010-2020) and employs a Difference-in-Differences (DID) model to assess the effects of low-carbon economic policies introduced in 2016 on CER.

Genome-wide identification and expression analysis of orphan genes in twelve (sub)species.

Unlabelled: Orphan genes (OGs), also known as lineage-specific genes, are species-specific genes that play a crucial role in species-specific adaptations to various stresses. Although OGs have been identified in several plant species, there is no information on OGs in banana genomes. This study aimed to systematically identify OGs in twelve banana (sub)species using comparative genomics.

Para-Bombay blood group: Report of a rare blood group.

Para-Bombay blood group is a rare blood group typically characterized by the absence of H antigens on red blood cell and the presence of ABH substances on secretion. It can be easily missed and often mistaken as blood group O without extended testing. Detection is important as it significantly affect transfusion management.

Red cell alloimmunization in multitransfused hepatobiliary patients at hospital Selayang.

Background: Transfusion support is vital for the management of patients with hepatobiliary disease. Repeated blood transfusions increase the risk of alloimmunization, i.e.

Efficacy and safety of a proprietary extract in skin health - a randomized, placebo-controlled clinical study in healthy volunteers.

Objectives: The concept of beauty from within is a growing trend in the market and people now look for oral supplements that can enhance the well-being of skin from within. Within this principle, a proprietary pomegranate extract (Grantria), standardized to ellagic acid, punicic acid and punicalagin, was developed using ADOP (Advanced Oil-Powder) technology and was clinically evaluated for its efficacy and safety in healthy adults.

Methods: This evaluation was carried out as a randomized, placebo-controlled clinical study for 60 days at a daily dose of 300 mg.

Nuclear Factor of Activated T Cells (NFAT) Proteins as Targeted Molecules in Diseases: A Narrative Review.

The nuclear factor of activated T cells (NFAT) is a key player in the NFAT pathway, regulating various cellular processes physiologically and pathologically. NFAT signaling is implicated in developing multiple diseases, such as cancer progression, that are associated with angiogenesis. Despite numerous studies on NFAT, there is still a dearth of information on the proteins and signaling pathway compared to other established pathways.

The effectiveness of real-life cognitive and physical interventions on cognitive functioning in healthy older adults: A systematic review of the effects of education and training duration.

Physical and cognitive interventions are deemed the primary methods of improving cognitive functioning in healthy older adults. However, the effectiveness of these interventions is still debated. This systematic review, synthesised findings from the literature on four different types of interventions: physical activities, cognitive training, cognitive stimulation and a combined intervention.

Translation, validation, and reliability of the Modified Occupational Questionnaire into Bahasa Melayu among older persons in Malaysia.

Introduction: A Modified Occupational Questionnaire (MOQ) is a self-report questionnaire that records the occupational engagement of an individual hourly, focusing on activity category, reason for doing the activity, value to self, and value to society. Understanding the patterns of occupational engagement and meaningful time use in older persons is crucial for predicting physical and psychological health and establishing occupation-based interventions to support healthy aging. However, the MOQ, originally developed in an English-speaking country and may potentially be less suitable for Malaysian older persons, who are predominantly Malay-speaking and have distinct cultural adaptations.

Linking microRNA to metabolic reprogramming and gut microbiota in the pathogenesis of colorectal cancer (Review).

Colorectal cancer (CRC), an emerging public health concern, is one of the leading causes of cancer morbidity and mortality worldwide. An increasing body of evidence shows that dysfunction in metabolic reprogramming is a crucial characteristic of CRC progression. Specifically, metabolic reprogramming abnormalities in glucose, glutamine and lipid metabolism provide the tumour with energy and nutrients to support its rapid cell proliferation and survival.