1,223 results match your criteria: "Malakoplakia"
Bladder (San Franc)
November 2024
Department of Pathology and Laboratory Medicine, Brantford General Hospital, Brantford, Ontario N3R 1G9, Canada.
Background: Malakoplakia is a rare granulomatous disease that commonly involves the genitourinary tract with the urinary bladder being the most frequently affected site. It is characterized by histiocytes containing distinct basophilic calcified inclusions called Michaelis-Gutmann bodies. It is believed to result from abnormally functioning macrophages, with inclusions representing calcifications around incompletely digested bacteria.
View Article and Find Full Text PDFJ Ayub Med Coll Abbottabad
November 2024
Jinnah Postgraduate Medical Centre, Karachi-Pakistan.
Eur J Microbiol Immunol (Bp)
December 2024
1Department of Microbiology, NSW Health Pathology, John Hunter Hospital, New Lambton Heights, NSW, Australia.
Prescottella (Rhodococcus) soli is a soil-dwelling organism not previously thought to be pathogenic in humans. We discuss the case of a 78-year-old male renal transplant recipient presenting with respiratory symptoms and multiple pulmonary nodules, found to be pulmonary malakoplakia secondary to infection with Prescottella (Rhodococcus) soli. Treatment was commenced with vancomycin, meropenem and azithromycin for an induction period of two weeks and continued with indefinite oral moxifloxacin and azithromycin with significant clinical improvement.
View Article and Find Full Text PDFBMC Infect Dis
October 2024
Department of Pathology, Mianyang Central Hospital, School of Medicine, University of Electronic Science and Technology of China, Mianyang, Sichuan, China.
Prostatic malakoplakia is an uncommon chronic inflammatory disorder, tumor-like but non-cancerous, the diagnosis of which pivots crucially on the identification of characteristic Michaelis-Gutmann bodies within the pathological tissue. We hereby present an inaugural case report of prostatic malakoplakia concurrent with sepsis caused by multidrug-resistant Escherichia coli, verified through blood culture and metagenomic next-generation sequencing (mNGS). The pathogenesis might be associated with infections by Escherichia coli, immune system irregularities, or lysosomal dysfunction.
View Article and Find Full Text PDFZhonghua Bing Li Xue Za Zhi
November 2024
Department of Pathology, Nanjing Drum Tower Hospital, the Affiliated Hospital of Nanjing University Medical School, Nanjing 210008, China.
Clin Nucl Med
January 2025
Diagnostic Radiology and Nuclear Medicine, Rush University Medical Center, Chicago, IL.
Malakoplakia is a rare inflammatory granulomatous disease that can produce a tumor-like appearance in nearly any organ system. Imaging findings of malakoplakia overlap with malignancy and tissue sampling are typically required for definitive diagnosis. We present a case of a 66-year-old woman with a previous history of liver adenocarcinoma status post resection that subsequently developed an intensely FDG-avid retroperitoneal mass on surveillance imaging.
View Article and Find Full Text PDFCase Rep Nephrol Dial
October 2024
Division of Nephrology, Department of Internal Medicine, Showa University Fujigaoka Hospital, Yokohama, Japan.
Cureus
September 2024
Histopathology, Postgraduate Institute of Medical Education and Research, Chandigarh, IND.
Malakoplakia, a rare granulomatous inflammatory condition, typically manifests in the genitourinary system. Its occurrence in the gallbladder is exceptionally uncommon, posing significant diagnostic challenges. A 68-year-old male presented with recurrent epigastric pain, and a suspicious gallbladder mass was found on imaging.
View Article and Find Full Text PDFBr J Radiol
January 2025
Department of Radiology, West China Hospital of Sichuan University, Chengdu, Sichuan 610041, China.
Asian J Surg
September 2024
Department of Pathology, The Second Affiliated Hospital of Dalian Medical University, China. Electronic address:
ACG Case Rep J
September 2024
Department of Gastroenterology and Hepatology, Cleveland Clinic, Weston, FL.
J Korean Neurosurg Soc
August 2024
Department of Neurosurgery, Daegu Catholic University School of Medicine, Daegu, Korea.
J Dermatol
August 2024
Department of Dermatology, University of Tokyo Graduate School of Medicine, Tokyo, Japan.
JPGN Rep
August 2024
Division of Gastroenterology, Hepatology, & Nutrition, Ann & Robert H. Lurie Children's Hospital of Chicago Northwestern University Feinberg School of Medicine Chicago Illinois USA.
J Vet Med Sci
September 2024
North lab, Hokkaido, Japan.
JAAD Case Rep
August 2024
SkinPath Solutions, Smyrna, Georgia.
Clin Nucl Med
August 2024
Nuclear Medicine, Daegu Catholic University School of Medicine, Daegu, Republic of Korea.
Head Neck Pathol
June 2024
Division of Dental and Oral Medicine, New York-Presbyterian/Queens, Flushing, New York, USA.
BMJ Case Rep
June 2024
Obstetrics and Gynaecology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand.
Front Med (Lausanne)
June 2024
Department of Gynecology, Ningbo No. 2 Hospital, Ningbo, Zhejiang, China.
BMC Nephrol
June 2024
Department of Medicine, Division of Pulmonary and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Malakoplakia is a rare inflammatory disorder believed to result from a defect in macrophage phagocytic function triggering a granulomatous reaction. It can present with genitourinary, gastrointestinal, or cutaneous manifestations in immunocompromised or, less commonly, immunocompetent hosts. We describe a case of renal malakoplakia in a young, otherwise healthy patient presenting with nephromegaly and sepsis following an E.
View Article and Find Full Text PDFClin Nucl Med
November 2024
From the Department of Nuclear Medicine, Max Super Speciality Hospital, Saket, New Delhi, India.
J Midlife Health
April 2024
Department of Obstetrics and Gynaecology, All India Institute of Medical Sciences, Bibinagar, Telangana, India.
Int J Surg Pathol
April 2024
Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of New Mexico Comprehensive Cancer Center, Albuquerque, NM, USA.
Front Oncol
April 2024
Department of Medical Ultrasound, West China Hospital, Sichuan University, Chengdu, China.