Antiquorum sensing and antibiofilm potential of biosynthesized silver nanoparticles of Myristica fragrans seed extract against MDR Salmonella enterica serovar Typhi isolates from asymptomatic typhoid carriers and typhoid patients.

Globally, Salmonella infection poses a major public health problem. Here, we report antibiofilm activity and quorum sensing inhibition of aqueous seeds extract of Myristica fragrans (nutmeg) and biosynthesized silver nanoparticles (AgNPs) against multidrug resistant (MDR) Salmonella enterica serovar Typhi (S. Typhi) isolated from typhoid patients and asymptomatic carriers.

Significance of allochthonous brackish water Halomonas sp. on biodegradation of low and high molecular weight polycyclic aromatic hydrocarbons.

The present study is aimed to isolate and identify polycyclic aromatic hydrocarbons (PAHs) degrading bacteria from brackish water and to assess the biodegradation efficiency against low and high molecular weight PAHs. Among 15 isolates, the isolate designated as RM effectively degraded 100 mg/L of phenanthrene (Phe) (67.0%), pyrene (Pyr) (63.

Effect of citric acid and vermi-wash on growth and metal accumulation of Sorghum bicolor cultivated in lead and nickel contaminated soil.

The aim of the present study is to assess the influence of vermi-wash (VW) and citric acid (CA) on Sorghum bicolor growth and phytoaccumulation of lead (Pb) and nickel (Ni) contaminated soil. The biomass of the S. bicolor has been enhanced by the addition of VW (24 and 26%) and CA (11 and 9%) in Pb and Ni contaminated soil, respectively.

Production and purification of laccase by sp. using millet husks and its pesticide degradation application.

Lignocellulosic agricultural bi-products, pearl millet (PM) and finger millet (FM) husks, were used for the production of laccase using sp. PS under solid-state fermentation (SSF). Abiotic variables such as substrate (PM, FM) concentration (1-5%), incubation time (24-96 h) and pH (5-10) were optimized using Response surface methodology (RSM) to maximize the laccase production.

Syntheses, physicochemical characterization, antibacterial studies on potassium morpholine dithiocarbamate nickel (II), copper (II) metal complexes and their ligands.

Organic molecule dithiocarbamate transition metal complexes are novel and very attractive pharmaceutical targets for the management and control of antibiotic resistant bacteria. The direct reaction has synthesized new transition metal nickel (II), copper (II) complexes of potassium morpholine dithiocarbamate (KCHNOS ) ligands and characterized by UV-visible spectroscopy, Fourier-transform infrared spectroscopy (FTIR), as well as NMR physicochemical techniques. Antibacterial bioefficacy of the ligand and its metal complexes has been investigated on the growth of Gram-positive ( MTCC 737, MTCC 1272) and the Gram-negative ( MTCC 657, MTCC 1457) bacteria.

Phytosynthesis of silver nanoparticles using Mangifera indica flower extract as bioreductant and their broad-spectrum antibacterial activity.

The present study focused on the evaluation of antibacterial property of silver nanoparticles (AgNPs) synthesized using mango flower extract. The morphology of the synthesized AgNPs was observed under transmission electron microscopy and the particles have shown spherical shape in the range of 10-20 nm. X-ray powder diffraction analysis confirmed the crystalline nature of the AgNPs.

In-vitro bio-mineralization of arsenic and lead from aqueous solution and soil by wood rot fungus, Trichoderma sp.

In the present study, we investigated the role of calcite, i.e., microbiologically-induced precipitate by ureolytic Trichoderma sp.

Effect of blue light on growth and exopolysaccharides production in phototrophic Rhodobacter sp. BT18 isolated from brackish water.

Rhodobacter sp. BT18, a phototrophic salt-resistant bacterium, was isolated from brackish water and screened for the production of exopolysaccharides (EPS). The effect of different light sources on the growth of Rhodobacter sp.

Myco-phytoremediation of arsenic- and lead-contaminated soils by Helianthus annuus and wood rot fungi, Trichoderma sp. isolated from decayed wood.

In the present study, Helianthus annuus grown in arsenic- (As) and lead- (Pb) contaminated soil were treated with plant-growth promoting fungi Trichoderma sp. MG isolated from decayed wood and assessed for their phytoremediation efficiency. The isolate MG exhibited a high tolerance to As (650mg/L) and Pb (500mg/L), and could remove > 70% of metals in aqueous solution with an initial concentration of 100mg/L each.

Biomimetic synthesis of silver nanoparticles using flower extract of Bauhinia purpurea and its antibacterial activity against clinical pathogens.

In the present study, we have reported an eco-friendly, rapid, and simple method for the synthesis of silver nanoparticles (AgNPs) using Bauhinia purpurea flower extract as non-toxic bioreducing agent. The formation of AgNPs was confirmed by UV-visible spectroscopy, transmission electron microscopy (TEM), scanning electron microscopy and energy-dispersive spectroscopy (SEM-EDS), Fourier transform infrared spectroscopy (FT-IR), and X-ray diffraction (XRD). The synthesized AgNPs were spherical in shape with an average size of 20 nm.

Isolation, identification and characterization of arsenic transforming exogenous endophytic sp. RPT from roots of .

The aim of the present study was to assess the arsenic (As) transformation potential of endophytic bacteria isolated from roots of plant. The endophytic bacterium was tested for minimal inhibitory concentration (MIC) against As. The endophytic strain RPT exhibited the highest resistance to As(V) (400 mg/l).

Biosynthesis of silver nanoparticles from Spirulina microalgae and its antibacterial activity.

The present work focuses on a low-cost, simple, and green synthesis of silver nanoparticles (AgNPs) by mixing AgNO solution with the extract of Spirulina platensis (SP) without any chemical reducing and/or capping agents. The green synthesis of AgNPs was confirmed by the color change from colorless to yellowish brown. The biosynthesis of AgNPs was further confirmed by UV-visible spectroscopy (UV-vis), Fourier transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD), biological transmission electron microscopy (Bio-TEM), and energy dispersive X-ray analysis (EDX).

Process optimization of biogas energy production from cow dung with alkali pre-treated coffee pulp.

Biogas production from cow dung with co-substrate agricultural waste is one of the most demanding technologies for generating energy in a sustainable approach considering eco-friendly. In the present study, coffee pulp (CP) was pre-treated with 1% NaOH and combined with various proportions of cow dung (CD) to explore its biogas producing potentiality. The optimization of the process was studied using Response surface methodology.

Drug-Target Interactions: Prediction Methods and Applications.

Identifying the interactions between drugs and target proteins is a key step in drug discovery. This not only aids to understand the disease mechanism, but also helps to identify unexpected therapeutic activity or adverse side effects of drugs. Hence, drug-target interaction prediction becomes an essential tool in the field of drug repurposing.

Bioremediation of heavy metals using an endophytic bacterium Paenibacillus sp. RM isolated from the roots of Tridax procumbens.

The aim of the present study was to assess the bioremediation potential of endophytic bacteria isolated from roots of Tridax procumbens plant. Five bacterial endophytes were isolated and subsequently tested for minimal inhibitory concentration (MIC) against different heavy metals. Amongst the five isolates, strain RM exhibited the highest resistance to copper (750 mg/l), followed by zinc (500 mg/l), lead (450 mg/l), and arsenic (400 mg/l).

Optimization of protease production from surface-modified coffee pulp waste and corncobs using Bacillus sp. by SSF.

The aim of the study was to identify new sources of substrate from agro-industrial waste for protease production using Bacillus sp., a local bacteria isolated from an agro-waste dumping site. The strain was identified as Bacillus sp.

rhizome extract mediated biosynthesis of silver nanoparticles and their bactericidal activity against human pathogens.

Silver nanoparticle (AgNP) synthesis and characterization is an area of vast interest due to their broader application in the fields of science and technology and medicine. Plants are an attractive source for AgNP synthesis because of its ability to produce a wide range of secondary metabolites with strong reducing potentials. Thus, the present study describes the synthesis of AgNPs using aqueous rhizome extract of (sweet flag).

Piper betle-mediated synthesis, characterization, antibacterial and rat splenocyte cytotoxic effects of copper oxide nanoparticles.

The study reports a simple, inexpensive, and eco-friendly synthesis of copper oxide nanoparticles (CuONPs) using Piper betle leaf extract. Formation of CuONPs was confirmed by UV-visible spectroscopy at 280 nm. Transmission electron microscopy (TEM) images showed that the CuONPs were spherical, with an average size of 50-100 nm.

Impact of an organic formulation (panchakavya) on the bioleaching of copper and lead in contaminated mine soil.

The study was aimed to evaluate the potential of organic formulation, panchakavya, for enhancing the biological leaching of Pb and Cu in contaminated mine soil. Response surface methodology based Box-Behnken design was used to optimize the variables such as incubation time, panchakavya concentration, and agitation rate. The maximum bioleaching (Pb=64% and Cu=49%) was observed after 54 h of incubation with 10 mL panchakavya at 120 rpm.

A comparative study on bioactive constituents between wild and propagated .

(Umbelliferae) has been used for centuries in Indian ayurvedic medicine for the treatment of a wide number of health disorders. The aim of this study was to estimate and compare the concentration of bioactive compounds between wild and propagated plants. A marked decrease in the total phenolic compounds, flavonoids, and ascorbic acid was observed between propagated and wild type plants collected from wet land habitat.

Sunroot mediated synthesis and characterization of silver nanoparticles and evaluation of its antibacterial and rat splenocyte cytotoxic effects.

A rapid, green phytosynthesis of silver nanoparticles (AgNPs) using the aqueous extract of Helianthus tuberosus (sunroot tuber) was reported in this study. The morphology of the AgNPs was determined by transmission electron microscopy (TEM). Scanning electron microscopy-energy-dispersive spectroscopy (SEM-EDS) and X-ray powder diffraction (XRD) analysis confirmed the presence of AgNPs.

Biosynthesis and characterization of silver nanoparticles using panchakavya, an Indian traditional farming formulating agent.

Synthesis of silver nanoparticles (AgNPs) with biological properties is of vast significance in the development of scientifically valuable products. In the present study, we describe simple, unprecedented, nontoxic, eco-friendly, green synthesis of AgNPs using an Indian traditional farming formulating agent, panchakavya. Silver nitrate (1 mM) solution was mixed with panchakavya filtrate for the synthesis of AgNPs.