Ruthenium-catalyzed hydroarylation reactions as the strategy towards the synthesis of alkylated arenes and substituted alkenes.

Metal-catalyzed hydroarylation reactions are always powerful tools in organic synthesis since they can form C-C or C-heteroatom bonds in an atom and step economic manner. Medicinally and biologically relevant scaffolds can be easily and efficiently synthesized using this strategy. By tuning the directing groups that are present on the arenes, regioselectivity can be induced to the C-H activation.

Copper-catalyzed Sonogashira reactions: advances and perspectives since 2014.

Transition metal catalyzed Sonogashira coupling reaction has evolved as an efficient pathway for the construction of C-C bonds. Initially, palladium cooperating with copper was considered as the efficient catalytic system for this reaction. However, nowadays there have been astonishing progress in copper catalyzed Sonogashira coupling reactions.

Applications of aryl-sulfinamides in the synthesis of N-heterocycles.

Enantiopure aryl-sulfinamides are important chiral auxiliaries in the asymmetric synthesis of amines and their derivatives. Here, we provide an overview of arylsulfinamide mediated asymmetric methods towards N-heterocycle synthesis. This methodology through sulfinylimines offers general access to structurally diverse piperidines, pyrrolidines, aziridines and their derivatives which represent the structural motif of many natural products and therapeutically important compounds.

Solvent-free synthesis of propargylamines: an overview.

Propargylamines are a class of compounds with many pharmaceutical and biological properties. A green approach to synthesize such compounds is very relevant. This review aims to describe the solvent-free synthetic approaches towards propargylamines A and KA coupling reactions covering the literature up to 2021.

Applications of -butanesulfinamide in the synthesis of N-heterocycles sulfinimines.

Chiral sulfinamides are among the best known chiral auxiliaries in the stereoselective synthesis of amines and their derivatives. The most extensively used enantiopure -butanesulfinamide emerged as the gold standard among many others over the last two decades. The present review attempts to provide an overview of -butanesulfinamide mediated asymmetric N-heterocycle synthesis sulfinimines and covers literature from 2010-2020.

Progress and prospects in copper-catalyzed C-H functionalization.

Copper-catalyzed C-H functionalization is becoming a significant area in organic chemistry. Copper is now widely used as a catalyst in organic synthesis as it is inexpensive and not very toxic. Functionalization of C-H bonds to construct wide varieties of organic compounds has received much attention in recent times.