Pixel to Pathology: A Prospective Cross-Sectional Study on the Role of Multidetector Computed Tomography in the Evaluation of Malignant Large Bowel Lesions With Histopathological Correlation.

Background And Objectives: Colorectal lesions can present as a mass or as focal or diffuse thickening of the colon wall and may also be associated with abnormalities in the perienteric region. Multidetector computed tomography (MDCT) enables simultaneous imaging of both extracolonic structures and the gut wall. It is instrumental in assessing tumor extent, detecting pericolic dissemination, including lymph node involvement, and identifying metastases.

Decoding Acute Scrotum: Diagnostic Accuracy of Ultrasound in Urgent Clinical Settings.

Background Acute scrotum is a medical emergency commonly encountered in clinical practice, particularly in pediatric and adolescent populations. It is characterized by sudden onset of scrotal pain and may involve swelling, redness, or tenderness. The most common etiologies include testicular torsion, epididymo-orchitis, trauma, and, less frequently, tumors.

Tuberculosis of the Cuboid: A Case Report.

Tuberculosis (TB) is a major global health concern, with skeletal TB representing a small fraction of total cases. Foot involvement is relatively uncommon in skeletal TB, and infections of the cuboid bone are especially rare. This case report describes an 18-year-old male who presented with pain and swelling in the dorsolateral left midfoot.

Efficacy of fractional carbon dioxide laser-assisted drug delivery in the management of post-burn scars - A prospective study.

Objectives: The objective of our study is to assess the efficacy of fractional carbon dioxide (CO2) laser-assisted drug delivery (LADD) in the management of post-burn scars.

Material And Methods: It is a prospective study conducted from March 2021 to February 2022, with 32 patients ranging in age from 9 to 52 years. The scars lasted anywhere from 6 months to 18 years.

Association between maternal vitamin D status during late pregnancy and acute lower respiratory tract infections and acute diarrheal disease during infancy - A cohort study.

Background: Acute lower respiratory tract infection (ALRI) and acute diarrheal disease (ADD) are the leading causes of mortality in children globally. There is emerging evidence of an association between maternal hypovitaminosis D and ALRI/ADD during infancy.

Objective: To determine whether maternal hypovitaminosis D (25(OH)D [<20 ng/ml] during late pregnancy is associated with increased risk of ALRI/ADD in their offspring during infancy.

A Retrospective Observational Study of Adverse Drug Reactions (ADR) Reported to ADR Monitoring Centre from 2010 to 2020.

Background: Adverse Drug Reactions (ADR) are one of the essential causes of hospital admissions and pose a significant clinical and economic burden on the healthcare system. The Adverse Drug Reaction Monitoring Centre (AMC) in JIPMER functioning under the Pharmacovigilance Programme of India (PvPI) plays a vital role in ensuring medication safety by routinely detecting and monitoring ADRs. Hence, this study aimed to assess the characteristics of ADR reported from 2010 to 2020 in AMC JIPMER and to detect signals, if any.

Real-Time Ultrasonography for the Placement of Caudal Epidurals for Thoracic Surgery in Infants: A Description of the Technique and Case Series.

Caudal epidural catheters threaded to the thoracic levels are increasingly utilized in infants undergoing thoracic and abdominal surgery, compared to lumbar or thoracic epidural techniques. Estimating catheter length traditionally relies on anatomical landmarks, but the lack of spine ossification in infants makes ultrasonography a valuable and noninvasive tool. We present 3 cases where real-time ultrasonography facilitated caudal to thoracic epidural catheter placement in infants undergoing thoraco-abdominal surgeries.

Evaluating the Diagnostic Efficacy of Computed Tomography in Appendicitis Cases With Negative Ultrasound Findings.

Introduction: Acute appendicitis (AA) is a prevalent cause of abdominal pain, and accurate diagnosis is critical to prevent complications such as perforation. While ultrasound (USG) is often the first imaging modality, its limitations necessitate alternative approaches, particularly in cases where USG results are negative.

Objectives And Aims: This study aims to evaluate the diagnostic accuracy of computed tomography (CT) in identifying appendicitis in patients presenting with negative USG findings.

Eating habit, body image, and gender - is there any association? - A comparative study among medical students from southern India.

Background: An increase in overweight and obesity among young adults are major health concerns which can influence their self-perception about body image. Body image has received a great deal of attention among young people. Body dissatisfaction is an extremely powerful construct that pervades our self-esteem, resulting in psychological impact and disordered eating.

Managing drug therapy-related problems and assessment of chronic diabetic wounds.

Type 2 diabetes mellitus (T2DM), responsible for most diabetes cases recorded worldwide, increases the risk of chronic wounds and amputation. Patients with T2DM appear to be more susceptible to delayed wound healing due to their treatment adherence. This review explores the specifics of polypharmacy, side effects, possible drug interactions and the importance of medication adherence for therapeutic efficacy.

Impact of Angiotensin Receptor Blockers (ARB) versus Other Antihypertensive Medication on Blood Pressure in Patients on Dialysis: A Meta-Analysis.

Introduction: Hypertension is an important factor driving mortality among dialysis patients. Angiotensin-II receptor blocker (ARB) has been effective similarly to angiotensin-converting enzymes (ACEs) but with a low incidence of side effects.

Methodology: The meta-analysis included all published studies that investigated the effect of ARB on the hypertension in adult dialysis patients (≥18 years).

Improving Palliative Care Research Reporting: A Guide to Reporting Guidelines.

Improving the quality of research reporting is crucial for addressing current challenges in palliative care, with academic journals playing a crucial role in promoting clear and comprehensive reporting through structured guidelines. These guidelines, such as Appraisal of Guidelines, Research, and evaluation, Consolidated Standards of Reporting Trials, Case Reports (CARE) guidelines, transparent reporting of evaluations with nonrandomized designs (TREND), transparent reporting of a multivariable prediction model for individual prognosis or diagnosis (TRIPOD), meta-analysis of observational studies in epidemiology (MOOSE) Checklist, methods of researching end-of-life care Statement, Preferred Reporting Items for Systematic Reviews and Meta-analyses, Standards for Quality Improvement Reporting Excellence 2.0, Strengthening the Reporting of Observational Studies in Epidemiology, standard protocol items: recommendations for interventional trials (SPIRIT), template for intervention description and replication (TIDieR) Consolidated Criteria for Reporting Qualitative Research and Standards for Qualitative Research, are instrumental in ensuring transparency by furnishing essential details for comprehending, replicating and applying research findings in clinical decision-making and systematic reviews.

Assessing the Correlation Between Anthropometric Measurements and Bone Densitometry As Indicators of Bone Health in Adult Women in the Community.

Introduction Osteoporosis is one of the most prevalent bone diseases in humans and is a significant global public health issue since it is a risk factor for age-related fractures. Fracture risk is significantly influenced by bone mineral density (BMD). Recent research has revealed that there are various genetic and environmental variables that are similar between obesity and osteoporosis.

Morphology, Morphometry, and Immunohistochemical Profile of Megakaryocytes and Bone Marrow Microenvironment in Disease Progression and Therapy Resistance in Chronic Myeloid Leukemia.

Background Tyrosine kinase inhibitors have revolutionized the treatment of chronic myeloid leukemia (CML) since the beginning of the century. However, resistance to therapy and the progression of disease tend to occur in certain patients. The bone marrow microenvironment may play a role in the disease outcome.

Management and Outcome of Pipkin Type I and Type II Femoral Head Fractures by Ganz Surgical Dislocation of the Hip.

Introduction Femoral head fractures, specifically Pipkin Type I and Type II, are uncommon injuries often linked with posterior hip dislocations. Management strategies for these fractures range from conservative treatments to various surgical procedures, with open reduction and internal fixation (ORIF) being a notable option. The surgical approach for ORIF varies, and due to the rarity of the injury, a standardized management protocol is lacking.