1,357 results match your criteria: "Mahasarakham University.[Affiliation]"

The invasion of blackchin tilapia in Thailand is a critical ecological threat affecting native biodiversity and destabilizing ecosystems. It is also resulting in significant ecological and socio-economic impacts. Originally from West Africa and introduced globally for aquaculture, blackchin tilapia thrive in Thailand's brackish and freshwater ecosystems because of their high reproductive rates, environmental adaptability, and trophic plasticity.

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Focal ischemia occurs when a cerebral artery becomes obstructed by an embolus or thrombus, leading to a rapid reduction in cerebral blood flow and significantly increasing the risk of mortality and disability. This condition is of particular concern in developing countries, where its prevalence is on the rise. Galangin, a flavonoid found in , shows strong antioxidant, anti-inflammatory and anti-apoptotic properties.

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Background: The alcohol industry uses many of the tobacco industry's strategies to influence policy-making, yet unlike the Framework Convention on Tobacco Control, there is no intergovernmental guidance on protecting policies from alcohol industry influence. Systematic assessment of alcohol industry penetration and government safeguards is also lacking. Here, we aimed to identify the nature and extent of industry penetration in a cross-section of jurisdictions.

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A new blood-brain barrier (BBB) in vitro model of tilapia (Oreochromis niloticus) was successfully established by co-culture with brain microvascular endothelial cell line TVEC-01 and brain astrocyte cell line TA-02 of tilapia. Experiments with the expression levels of BBB-related genes, TEER value detection and 4-h water-leaking test have shown that the BBB in vitro model has an excellent barrier effect. In bacterial penetration experiments, the pathogenic strain of Streptococcus agalactiae was able to pass through the BBB in vitro model and initiate a series of immune responses, among which TA-02 contributed to the expression of pro-inflammatory cytokines and TVEC-01 contributed to the expression of anti-inflammatory cytokines, providing an excellent research tool and theoretical basis for further study of meningitis.

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Introduction: Infection with liver flukes (Opisthorchis viverrini) is partly attributed to their ability to thrive in sub-basin habitats, causing the intermediate host to remain within the watershed system throughout the year. It is crucial to conduct spatial monitoring of fluke infection at a small basin analysis scale as it helps in studying the spatial factors influencing these infections. The number of infected individuals was obtained from local authorities, converted into a percentage, and visually represented as raster data through a heat map.

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Article Synopsis
  • * This study systematically reviewed literature and pooled utility estimates from 14 high-quality studies involving 3,664 PAD patients, using established classification systems like Rutherford and Fontaine.
  • * The findings indicated a pooled utility score of 0.67 for Rutherford categories and 0.68 for Fontaine stages, suggesting that PAD has a similar health utility to other chronic diseases and can inform cost-utility analyses in PAD management.
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Article Synopsis
  • The study investigates the colony-stimulating factor-1 receptor (MCSFR) in rainbow trout, identifying four gene variants, including two previously unrecognized, and explores their expression levels in various tissues.
  • The protein structure of MCSFRs includes five immunoglobulin-like domains and suggests a conserved function across species.
  • Following infection with Yersinia ruckeri, different MCSFR paralogues exhibit unique expression patterns, showing complex regulatory mechanisms influenced by various stimuli, enhancing the understanding of immune responses in fish.
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Cervical cancer remains a significant global health challenge, with high mortality rates and a pressing need for more effective therapeutic options. This study investigates the effects of an ethanolic extract from the fruit of Piper retrofractum (PR) on proliferation and apoptosis in cervical cancer cells. We evaluated the cytotoxicity of the crude ethanolic extract of PR using the sulforhodamine B and colony formation assay.

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Background: Renal blood flow (RBF) is regulated by an autonomic nervous system and is reduced in older adults. Massage has been previously found to increase blood flow.

Objective: This two-armed double-blind, randomized controlled trial aimed to investigate the immediate effects of Thai foot massage (TFM) on RBF, psychological stress, and heart rate variability (HRV) in older adult persons.

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This study addresses the valorization of duck blood, an underutilized protein-rich by-product from the poultry industry, into bioactive protein hydrolysates with antioxidant and ACE inhibitory properties. Raw and heat-treated duck blood were compared as substrates for enzymatic hydrolysis using Neutrase and Papain. Gel electrophoresis revealed that heat treatment reduced fibrinogen content, while FTIR analysis showed that heat treatment modified the protein structure, increasing β-sheet content from 21.

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Background: Leucocytozoonosis, a parasitic disease of birds, is caused by haemosporidian protozoan parasites of the genus Leucocytozoon, which infect diverse avian species, including poultry. These parasites are transmitted by several black fly species, but knowledge of the factors determining the diversity and prevalence in these vectors, which is crucial for fully understanding disease epidemiology, is largely unexplored. In this study, we investigated factors associated with the prevalence and diversity of Leucocytozoon species in black flies from Thailand.

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This study examined the potential of duckweed powder (DWP) on in vitro fermentation characteristics, nutrient degradability, microbial change, and methane (CH) production using in vitrostudy technique. This investigation used a 2 × 6 factorial arrangement in a completely randomized design (CRD) by different roughage-to-concentrate (R: C) ratios of 60:40 and 40:60 combined with DWP supplementation levels at 0, 2, 4, 6, 8, and 10% of the total dry matter (DM) substrate, respectively. There was an interaction effect by R: C ratios combined with DWP supplementations that changed gas production rate, pH value (4 h; h), volatile fatty acid (VFA) (8 h), in vitro dry matter degradability (IVDMD) at 12 h, and concentration of ammonium nitrogen (NH-N) (p < 0.

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Exploring the Nutritional Potential of Spent Coffee Grounds as a Substitute for Rice Bran in Feeds for Nile tilapia, : An Evaluation of Growth Performance and Biological Indices.

Aquac Nutr

March 2024

Unit of Excellence "Physiology and Sustainable Production of Terrestrial and Aquatic Animals" Division of Fisheries, School of Agriculture and Natural Resources, University of Phayao, Phayao 56000, Thailand.

This study aimed to assess the viability of replacing rice bran with spent coffee grounds (SCG) in the diets of (average body weight, 48.8 ± 0.42 g).

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First blood-meal record of Simulium asakoae (Diptera: Simuliidae) in Malaysia, with notes on its distribution in Asia and status as a potential vector.

Trop Biomed

September 2024

Higher Institution Centre of Excellence (HICoE), Tropical Infectious Diseases Research & Education Centre (TIDREC), 50603, Universiti Malaya, Kuala Lumpur, Malaysia.

Simulium asakoae Takaoka and Davies has been confirmed to bite humans and has been incriminated as a vector of blood protozoan parasites of the genera Leucocytozoon and Trypanosoma, as well as an unknown filarial parasite in Thailand. However, its attraction to humans has remained uninvestigated in Malaysia. Recently, 27 black flies were collected in Pahang, Malaysia, of which 25 were captured in CO-baited Malaise traps and two were collected from humans during trapping activity.

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O-methylguanine-DNA methyltransferase (MGMT) is a DNA damage repair enzyme. The roles of this enzyme in immune cells remain unclear. In this study, we explored the roles of MGMT in bone marrow-derived murine macrophages (BMMs) via the use of MGMT knockout (KO) mice.

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This research presents the discovery of two novel taxa, Curcuma sumonii Saensouk, P.Saensouk, Boonma & Techa, and C. wanchaii Saensouk, P.

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Encapsulation of ɣ-Aminobutyric Acid Compounds Extracted from Germinated Brown Rice by Freeze-Drying Technique.

Molecules

October 2024

Public Health and Environmental Policy in Southeast Asia Research Cluster (PHEP-SEA), Mahasarakham University, Kham Riang, Maha Sarakham 44150, Thailand.

Gamma-aminobutyric acid (GABA) from plants has several bioactivities, such as neurotransmission, anti-cancer cell proliferation, and blood pressure control. Its bioactivities vary when exposed to pH, heat, and ultraviolet. This study analyzed the protective effect of the GABA encapsulation technique using gum arabic (GA) and maltodextrin (MD) and the freeze-drying method.

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Preparation and Characterization of Cellulose/Silk Fibroin Composite Microparticles for Drug-Controlled Release Applications.

Polymers (Basel)

October 2024

Biodegradable Polymers Research Unit, Department of Chemistry and Centre of Excellence for Innovation in Chemistry, Faculty of Science, Mahasarakham University, Mahasarakham 44150, Thailand.

Microparticles derived from biomaterials are becoming increasingly popular for application in drug delivery systems. In this study, the water-in-oil (W/O) emulsification-diffusion method was used to create cellulose (C), silk fibroin (SF), and C/SF composite microparticles. We then observed the morphology of all obtained microparticles using scanning electron microscopy (SEM), evaluated their functional groups using attenuated total reflection-Fourier transform infrared spectroscopy (ATR-FTIR), and conducted thermogravimetric analysis using a thermogravimetric analyzer (TGA).

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Effect of the MONTANIDE™ IMS 1312 adjuvant on the innate and adaptive immune responses of Nile tilapia (Oreochromis niloticus) against Streptococcusagalactiae through immersion vaccination.

Fish Shellfish Immunol

December 2024

Laboratory of Fish Immunology and Nutrigenomics, Applied Animal and Aquatic Sciences Research Unit, Division of Fisheries, Faculty of Technology, Mahasarakham University, Khamriang Sub-District, Kantarawichai, Mahasarakham, 44150, Thailand. Electronic address:

Streptococcus agalactiae is a common pathogenic bacterium caused of streptococcosis, which has a negative impact on Nile tilapia aquaculture. Numerous vaccines have been developed recently to combat this disease, which are key components of global health efforts to prevent disease outbreaks. MONTANIDE™ IMS 1312 is a micro-emulsion recommended for immersion of fish.

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Ibuprofen adsorption and detection of pristine, Fe-, Ni-, and Pt-doped boron nitride nanotubes: A DFT investigation.

J Mol Graph Model

October 2023

Multidisplinary Research Unit of Pure and Applied Chemistry, Department of Chemistry, Faculty of Science, Mahasarakham University, Kantharawichai, Maha Sarakham, 44150, Thailand; Supramolecular Chemistry Research Unit, Department of Chemistry, Faculty of Science, Mahasarakham University, Kantharawichai, Maha Sarakham, 44150, Thailand. Electronic address:

The main challenge has been focused on ibuprofen drug detection and adsorption of boron nitride nanotube (BNNT) doping with transition metal (TM = Fe, Ni, and Pt) atoms using the density functional theory calculation in gas and water phases. The geometrical structures, adsorption energies, solvation energies, and electronic properties were examined. The optimized geometries show that the ibuprofen molecule oriented itself at different bond distances and angles with respect to BNNT surface.

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In low- and middle-income countries (LMICs), barriers such as low system readiness, contextual mismatches, and resource limitations impede effective implementation of evidence-based interventions. This commentary offers insights into overcoming these challenges with a case study of the PRISM project, designed to reduce behavioral and psychological symptoms of dementia in older adults living in Thailand. The case highlights how combining two evidence-based models - the clinical intervention and the implementation science process enhances program success.

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The COVID-19 pandemic continues to pose significant challenges to global public health, necessitating the development of effective vaccination strategies to mitigate disease transmission. In Thailand, the COVID-19 epidemic has undergone multiple waves, prompting the implementation of various control measures, including vaccination campaigns. Understanding the dynamics of disease transmission and the impact of vaccination strategies is crucial for guiding public health interventions and optimizing epidemic control efforts.

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Article Synopsis
  • * Factors like losing family members to COVID-19, smoking, and alcohol consumption increased the risk of mental health issues and contributed to lower quality of life (QOL).
  • * The study highlights a strong relationship between mental health and QOL, emphasizing the need for targeted interventions to support affected individuals and improve overall well-being.
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Article Synopsis
  • * Phylogenetic and structural analyses confirmed the naming of these CCRs, and their expression increased significantly in the spleen after bacterial infection, highlighting their importance in combating pathogens.
  • * Selection pressure analysis showed varying evolutionary pressures on these receptors, with molecular docking revealing potential ligand interactions for improved understanding of their functions in immune responses.
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