Applications of 3D Bioprinting in Oral and Maxillofacial Surgery: An Insight.

Oral and maxillofacial surgery has seen various advancements throughout years. From dental implants to 3D printing, every advancement this field has witnessed has taken it one step ahead into the future. Reconstructive surgeries in oral and maxillofacial surgery have evolved drastically over the years.

Nanoengineering TiO for evaluating performance in dye sensitized solar cells with natural dyes.

The current study employs nanoengineering diatom and TiO NPs to form diatom-Si-TiO nanoengineered structures to fabricate a dye sensitized solar cell (DSSC) (-DSSC). This was characterized and spin coated on a Fluorine-doped Tin Oxide (FTO) anode plate. The counter cathode was prepared by spin coating graphene oxide on a FTO glass plate and using Lugol's iodine as an electrolyte.

Development of QSPR Strategy for the Solubility Prediction.

Introduction: QSPR modelling is one of the major computational tools used to correlate molecular characteristics with physiochemical properties of molecules. In present work, QSPR models are formed using AIC and VIF multicollinearity indicators for descriptors selection taking solubility data of Paclitaxel prodrugs. Geometry optimization of these Paclitaxel prodrugs was performed at the PM6 and AM1levels using Gaussian software.

Molecular Docking and Molecular Dynamics Simulation Based Approach to Explore the Dual Inhibitor Against HIV-1 Reverse Transcriptase and Integrase.

Background: HIV integrase (IN) and reverse transcriptase (RT) are key enzymes for the replication of HIV-1. DNA polymerase and ribonuclease H (RNase H) are the two catalytic domains of HIV-1 RT which are validated as drug targets because of their essence for replication. IN and RNase H domain of RT shares striking structural similarity; it contains conserved DDE triad (two aspartates and one glutamate) and a pair of divalent Mg2+/Mn2+ ions at their catalytic core domain.

Microbial pectinases: an ecofriendly tool of nature for industries.

Pectinases are the growing enzymes of biotechnological sector, showing gradual increase in their market. They hold a leading position among the commercially produced industrial enzymes. These enzymes are ecofriendly tool of nature that are being used extensively in various industries like wine industry; food industry; paper industry for bleaching of pulp and waste paper recycling; in the processing of fruit-vegetables, tea-coffee, animal feed; extraction of vegetable oil and scouring of plant fibres.

Effect of complete decongestive therapy and a home program for patients with post mastectomy lymphedema.

[Purpose] Post mastectomy lymphedema is common among breast cancer survivors. It leads to physical discomfort and functional impairment. Rehabilitation forms the mainstay of treatment and is multidisciplinary.

Mechanistic insight of drug resistance with special focus on iron in estrogen receptor positive breast cancer.

Estrogens along with their receptors are required for the normal physiological development of women. However, in altered physiological conditions a high level of estrogens acts either as initiator or progressor of breast cancer. Approximately in 75% of estrogen dependent breast cancer cases estrogen receptors (ERs) are held responsible.

Knockdown of receptor for advanced glycation end products attenuate 17α-ethinyl-estradiol dependent proliferation and survival of MCF-7 breast cancer cells.

Background: 17α-ethinyl-estradiol (17α-EE), a synthetic estrogen is the world's most widely and commonly used orally bioactive estrogen. Currently, 17α-EE is in use in all formulations of contraceptive pills and is implicated in the complication of breast cancer. Receptor for advanced glycation end products (RAGE) is a cell surface immunoglobulin class of molecule.