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Article Synopsis
  • The study investigated the effects of erythropoietin (EPO) on bacterial translocation in rats with induced colitis.
  • Rats were divided into three groups: a control group, a colitis group (which received no treatment), and an EPO-treated group that received EPO injections after colitis induction.
  • EPO treatment resulted in significantly reduced inflammation and lower levels of bacterial translocation in various organs compared to the colitis group, indicating EPO's potential protective effects against colitis.
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Background: Postoperative epidural adhesion is a frequent cause of failed back surgery syndrome, manifesting with back and leg pain or neurologic deficits. Development of preventive measures for epidural adhesion after laminectomy is critical to improve outcomes of lumbar surgery. We hypothesized that positive effects of topical application of Contractubex (CTX) gel and benzothiazole (BT) individually and in combination could aid in preventing epidural fibrosis in a rat laminectomy model.

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