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Red blood cell transfusion in premature infants leads to worse necrotizing enterocolitis outcomes.
J Surg Res
June 2017
Division of Newborn Medicine, Department of Pediatrics, Magee-Womens Hospital and Children's Hospital of Pittsburgh of University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania. Electronic address:
Background: Necrotizing enterocolitis (NEC) is a severe intestinal disease of premature infants with high mortality. Studies suggest a causative relationship between red blood cell (RBC) transfusion and NEC; however, whether RBC transfusion leads to worse outcomes in NEC is unknown. We sought to determine whether RBC transfusion was associated with an increased risk of surgical NEC and mortality.
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