308 results match your criteria: "Madurai Medical College.[Affiliation]"
Indian J Nephrol
July 2022
Institute of Nephrology, Madras Medical College, Chennai, Tamil Nadu, India.
Introduction: Acute kidney injury (AKI) frequently complicates severe acute pancreatitis (SAP) among the critically ill. We studied clinical profile and risk factors predicting mortality in SAP-AKI.
Materials And Methods: We conducted a prospective observational study of 68 patients with SAP-AKI from September 2015 to September 2019.
Bioinformation
March 2022
Department of Biochemistry, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, India.
We document the Molecular docking analysis of bioactive compounds from with PPAR gamma for further consideration in drug discovery for T2DM.
View Article and Find Full Text PDFBioinformation
March 2022
Department of Biochemistry, Allied Health science, Dr. M.G.R Educational and Research Institute, Chennai India.
Diabetes mellitus is a group of metabolic disorders that has risen to become the third most common cause in humans in recent years. The development of new bioactive substances from natural sources is a relatively new area. Flavonoids are believed to have a variety of beneficial properties in nature, including anti-inflammatory, antimicrobial, anticancer, antioxidant, neuroprotective, and anti-HIV properties.
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March 2022
Department of Biochemistry, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, India.
We report the molecular docking analysis of four analogues of metformin [1-Carbamimidoyl-1,2-dimethylguanidine hydrochloride, Metformin hydrochloride, N1,N1-Dimethyl-N5-methylbiguanide hydrochloride, and N1,N1,N5,N5-Tetrakis (methyl-biguanide hydrochloride] with GSK3.
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March 2022
Department of Biochemistry, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, India.
Natural remedies from medicinal plants are known to be effective and reliable appropriate medicine for illnesses. The current research examined Plectranthus amboinicus' anti diabetic property by docking the bioactive compounds of certain target proteins. We document the molecular docking analysis of bioactive compounds from Plectranthus amboinicus with protein Glucokinase.
View Article and Find Full Text PDFCureus
November 2022
Internal Medicine, Saint Michael's Medical Center, Newark, USA.
Gastrointestinal stromal tumors (GISTs) are uncommon GI tract cancers that develop from immature mesenchymal cells. It might be difficult to get an early diagnosis of people with small bowel GISTs, which can cause delays in therapy. We present here a case of a 62-year-old male with an incidental finding of a small intestine GIST during the workup for umbilical hernia.
View Article and Find Full Text PDFIndian J Anaesth
September 2022
Department of Anaesthesiology and Intensive Care, Gian Sagar Medical College and Hospital, Banur, Patiala, Punjab, India.
Indian J Dermatol
January 2022
Department of Dermatovenereology, Madurai Medical College, Panagal Road, Madurai, Tamil Nadu, India.
Indian J Endocrinol Metab
September 2022
Department of Endocrinology, Madurai Medical College, Madurai, Tamil Nadu, India.
Aim: The prevalence of childhood and adolescent obesity is increasing worldwide as well as in India. Prader--Willi syndrome (PWS) is one of the most common causes of syndromic obesity with varied clinical manifestations across different lifespan. Herewith, we describe clinical and molecular characteristics of eight PWS who were diagnosed in an obesity clinic of tertiary care hospital.
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August 2022
Internal Medicine, Jackson Park Hospital, Chicago, USA.
Serotonin syndrome (SS) is a potentially life-threatening condition caused by drugs that act on serotonergic receptors or alter serotonin metabolism. We present a case of SS in a middle-aged female who was taking trazodone and sertraline as her home medications and developed SS after being started on quetiapine during her hospital course. A 54-year-old female with a past medical history of dementia and bipolar disorder was brought to the emergency department from a nursing home for altered mental status.
View Article and Find Full Text PDFNeurol India
July 2022
Department of Endocrinology, Government Rajaji Hospital and Madurai Medical College, Madurai, Tamil Nadu, India.
Fahr's disease is an idiopathic basal ganglia calcification with autosomal dominant inheritance. Prior to diagnosing Fahr's disease based on computed tomography (CT) and/or magnetic resonance imaging (MRI) of the brain, one should rule out hypoparathyroidism (HP), and pseudohypoparathyroidism (PHP). Treatments of these conditions are entirely different.
View Article and Find Full Text PDFJ Nephrol
January 2023
Department of Nephrology, Madurai Medical College, Madurai, India.
Indian J Endocrinol Metab
April 2022
Department of Endocrinology, Madurai Medical College, Madurai, Tamil Nadu, India.
Aims And Objectives: Clinical, biochemical, and radiological profiles of Addison's disease and to assess the various etiological spectrum of primary adrenal insufficiency (PAI) in adults.
Materials And Methods: A retrospective cohort study was carried out in the Department of Endocrinology, Madurai Medical College, Madurai between January 2014 and January 2021 over a 7-year period.
Inclusion Criteria: All the patients with clinical symptoms and or signs of suspected PAI, such as hyperpigmentation, weight loss, persistent nausea or vomiting, fatigue, and hypotension, were recruited.
Case Rep Nephrol Dial
March 2022
Department of Nephrology, Madurai Medical College and Government Rajaji Hospital, Madurai, India.
Indian J Surg Oncol
March 2022
Department of Surgical Oncology, Madurai Medical College, Tamilnadu, India.
Central compartment nodes of neck are the first echelon nodes in papillary thyroid cancers (PTC). This study analyses the adverse parameters associated with central compartment nodal metastasis in cN0 PTC and also the usefulness of performing central compartment neck dissection routinely. A total of 236 patients with cNo PTC who underwent prophylactic central compartment neck dissection, from January 2008 to June 2017 in the Department of Oncology, Madurai Medical College, were included in study.
View Article and Find Full Text PDFIndian J Endocrinol Metab
February 2022
Department of Endocrinology, Madurai Medical College, Madurai, Tamil Nadu, India.
Aim: Congenital adrenal hyperplasia (CAH) is an autosomal recessive disorder of the adrenal steroidogenic pathway. The most common form of CAH is due to 21-hydroxylase deficiency resulting from mutations in gene. The present study aimed to identify common gene mutations, phenotype correlation, and to analyze the segregation pattern in CAH patients, parents, and siblings.
View Article and Find Full Text PDFInt J Nephrol Renovasc Dis
March 2022
Department of Nephrology, Madurai Medical College, Madurai, Tamil Nadu, India.
Introduction: Sleep disturbances are common in patients with end-stage kidney disease on hemodialysis (hemodialysis population: HDP). Higher rates of primary sleep disorders, demographic characteristics, metabolic abnormalities, and the efficacy of treatment place HDP at higher risk. The pattern observed is delayed onset of sleep, frequent awakening episodes, insomnia, sleep apnoea, excessive daytime sleepiness, restless leg syndrome, abnormal limb movements, pain in limbs, confusion, and nightmares.
View Article and Find Full Text PDFJ Family Med Prim Care
January 2022
Postgraduates, Institute of Community Medicine, Madurai Medical College, Madurai, Tamil Nadu, India.
Introduction: COVID is a new disease; understanding the transmission dynamics and epidemiological characteristics may help in developing the effective control measures. The study is done 1. To determine the various factors influencing the acquisition of COVID-19 infection among high-risk contacts 2.
View Article and Find Full Text PDFIndian J Endocrinol Metab
January 2022
Department of Endocrinology, Government Rajaji Hospital and Madurai Medical College, Madurai, Tamil Nadu, India.
Disorders of sexual development (DSDs) are heterogenous group of disorders characterized by discrepancy in chromosomal, gonadal, and phenotypic sex. DSD is a Medico-Social Emergency. 5 α reductase type 2 deficiency is one of the rare causes of 46 XY DSD.
View Article and Find Full Text PDFKidney Res Clin Pract
May 2022
Department of Nephrology, Madurai Medical College, Madurai, India.
Background: The coronavirus disease 2019 (COVID-19) vaccine is not readily available in many countries where dosing interval is spaced more than ideal. Patients with chronic kidney disease, especially those on maintenance hemodialysis, have a tendency for a reduced immune response. This study was undertaken to demonstrate the distinct humoral immune response to the viral vector COVID-19 vaccine in patients with kidney failure receiving maintenance hemodialysis.
View Article and Find Full Text PDFMolecules
January 2022
Central Research Laboratory, Melmaruvathur Adhiparasakthi Institute of Medical Sciences and Research, Melmaruvathur 603319, India.
Osteoporosis is a skeletal disease that is both systemic and silent characterized by an unbalanced activity of bone remodeling leading to bone loss. Rising evidences demonstrate that thyroid stimulating hormone (TSH) has an important role in the regulation on the metabolism of bone. However, TSH regulation on human osteoblast essential transcriptional factors has not been identified.
View Article and Find Full Text PDFJ Pharm Bioallied Sci
November 2021
Department of OMFS, Sri Venkateshwara Dental College and Hospital, Chennai, Tamil Nadu, India.
Aim: To evaluate the levels of leptin in gingival crevicular fluid (GCF) during orthodontic tooth movement and to find the role of leptin as a mediator for tooth movement.
Materials And Methods: GCF was collected from 25 subjects and the levels of leptin in it were measured. Sample (A) pretreatment, (B) 6 h after applying retractive orthodontic force from right side canine, (C) without retractive force from left side canine, and after 21 days from right canine (D), and left canine (E).
Clin Epidemiol Glob Health
December 2021
Institute of Community Medicine, Madurai Medical College, Madurai, Tamil Nadu, India.
Background: COVID-19 pandemic causes major impact on economic, physical, mental well-being of people all over the world. Doctors are working in stressful, unprepared, limited resource setting, and they are under the continuous threat of getting infection. Managing mental health of these warriors is great importance.
View Article and Find Full Text PDFJ Med Genet
October 2022
Cardiovascular Biology and Disease Theme, Institute for Stem Cell Science and Regenerative Medicine, Bangalore, Karnataka, India
Background: Hypertrophic cardiomyopathy (HCM) is a genetic heart muscle disease with preserved or increased ejection fraction in the absence of secondary causes. Mutations in the sarcomeric protein-encoding genes predominantly cause HCM. However, relatively little is known about the genetic impact of signalling proteins on HCM.
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