Automated Segmentation of Nuclei in Breast Cancer Histopathology Images.

The process of Nuclei detection in high-grade breast cancer images is quite challenging in the case of image processing techniques due to certain heterogeneous characteristics of cancer nuclei such as enlarged and irregularly shaped nuclei, highly coarse chromatin marginalized to the nuclei periphery and visible nucleoli. Recent reviews state that existing techniques show appreciable segmentation accuracy on breast histopathology images whose nuclei are dispersed and regular in texture and shape; however, typical cancer nuclei are often clustered and have irregular texture and shape properties. This paper proposes a novel segmentation algorithm for detecting individual nuclei from Hematoxylin and Eosin (H&E) stained breast histopathology images.

DNA barcoding of mayflies (Insecta: Ephemeroptera) from South India.

In this study, DNA barcodes were generated for 40 species belonging to 32 genera under 10 families of Ephemeroptera from South India. Nucleotide sequence divergences were calculated using the Kimura two-parameter distance model and a neighbour-joining analysis was performed to provide a graphic display of the patterns of divergence among the species. This study demonstrates that COI barcoding is effective in discriminating among the mayfly species of South India, and provides a reference library for their future molecular identification.

A new jumping spider of the genus Stenaelurillus Simon, 1886 from India (Araneae: Salticidae: Aelurillina).

The genus Stenaelurillus Simon, 1886 is known from 35 species worldwide, including 27 species from Africa and eight from Asia (four species known from India, one from Iran, one from China, one from Tibet and one from Vietnam) (World Spider Catalog 2016). The four species known from India are S. albus Sebastian et al.

Overhead tank is the potential breeding habitat of Anopheles stephensi in an urban transmission setting of Chennai, India.

Background: Wells and overhead tanks (OHT) are the major breeding sources of the local malaria vector, Anopheles stephensi in the Indian city of Chennai; they play a significant role in vector breeding, and transmission of urban malaria. Many other man-made breeding habitats, such as cemented cisterns/containers, barrels or drums, sumps or underground tanks, and plastic pots/containers are maintained to supplement water needs, temporarily resulting in enhanced mosquito/vector breeding. Correlating breeding habitats with immature vector abundance is important in effective planning to strengthen operational execution of vector control measures.

Abundant and Altered Expression of PIWI-Interacting RNAs during Cardiac Hypertrophy.

Background: The discovery of PIWI-interacting RNAs (piRNAs) has fundamentally changed our understanding of post transcriptional regulation of transposons and other genes. Unlike miRNA and siRNA, the piRNAs are the most abundant but least studied RNA species in mammals. Although the expression of PIWI proteins and piRNAs has long been regarded as germline specific, increasing evidences suggest the expression of piRNAs in somatic cells.

Role of triton X-100 and hydrothermal treatment on the morphological features of nanoporous hydroxyapatite nanorods.

Hydroxyapatite (HA) particles were synthesized using Ca(NO3)2·4H2O and (NH4)2HPO4 as precursors with varying contents of non-ionic surfactant viz., triton X-100 (organic modifier) via co-precipitation method followed by hydrothermal treatment. The prepared HA particles have been characterized by X-ray diffraction (XRD), Fourier Transform Infrared spectroscopy (FT-IR), Energy Dispersive X-ray Analysis (EDX), High Resolution Scanning Electron Microscopy (HRSEM), High Resolution Transmission Electron Microscopy (HRTEM) and Nitrogen adsorption-desorption experiments.

TiO-NiO p-n nanocomposite with enhanced sonophotocatalytic activity under diffused sunlight.

TiO-NiO composites with p-n junction were developed by assembling p-type NiO on n-type TiO using ultrasound assisted wet impregnation method. The sonophotocatalytic efficiencies of pure TiO and TiO-NiO composites were evaluated under diffused sunlight using methyl orange (MO) as a model pollutant. The impregnation of NiO nanoparticles on TiO considerably enhanced the optical absorption in visible region (500-800nm) due to the formation of p-n junctions at the interface between TiO and NiO.

Larvicidal and repellent potential of Zingiber nimmonii (J. Graham) Dalzell (Zingiberaceae) essential oil: an eco-friendly tool against malaria, dengue, and lymphatic filariasis mosquito vectors?

Mosquitoes (Diptera: Culicidae) are important vectors of terms of public health relevance, especially in tropical and sub-tropical regions. The continuous and indiscriminate use of conventional pesticides for the control of mosquito vectors has resulted in the development of resistance and negative impacts on non-target organisms and the environment. Therefore, there is a need for development of effective mosquito control tools.

Contribution to the knowledge of the mayfly genus Teloganella Ulmer, 1939 (Ephemeroptera: Ephemerelloidea).

We consider the genus Janohyphella Selvakumar, Sivaramakrishnan & Jacobus, 2014 (Ephemeroptera:Teloganodidae) to be a new junior synonym of Teloganella Ulmer, 1939 [=Janohyphella, syn. n.] based on comparative examination of new and previously studied materials from Malaysia and India.

Crystal structure of the adduct (4-chloro-phen-yl)(4-hy-droxy-piperidin-1-yl)methanone-(4-chloro-phen-yl)(piperidin-1-yl)methanone (0.75/0.25).

In the title compound, 0.75C12H14ClNO2·0.25C12H14ClNO, which is an adduct comprising 0.

Crystal structure of (4-hy-droxy-piperidin-1-yl)(4-methyl-phen-yl)methanone.

In the title compound, C13H17NO2, the dihedral angle between the planes of the piperidine and benzene rings is 51.7 (2)°. The bond-angle sum around the N atom [359.

Crystal structure of (4-hy-droxy-piperidin-1-yl)[4-(tri-fluoro-meth-yl)phen-yl]methanone.

The title compound, C13H14NO2F3, crystallises with two mol-ecules, A and B, in the asymmetric unit, with similar conformations. The dihedral angles between the piperidine and phenyl rings are 83.76 (2) and 75.

Crystal structure of [4-(chloro-meth-yl)phen-yl](4-hy-droxy-piperidin-1-yl)methanone.

The title compound, C13H16ClNO2, crystallized with two independent mol-ecules in the asymmetric unit (A and B). The piperidinol ring in mol-ecule B is disordered over two positions with a site occupancy ratio of 0.667 (5):0.

Syndemics of depression, alcohol use, and victimisation, and their association with HIV-related sexual risk among men who have sex with men and transgender women in India.

We examined the presence and co-occurrence of psychosocial health conditions (depression, frequent alcohol use, and victimisation) among men who have sex with men (MSM) and transgender (TG) women in India, and their cumulative association with sexual risk. A survey questionnaire was administered among a convenience sample of 600 participants (MSM = 300; TG women = 300) recruited through six non-governmental organisations in four states. Prevalences of the number of psychosocial health conditions among MSM were: none = 31.

Crystal structure of (E)-1-(1-hy-droxy-naphthalen-2-yl)-3-(2,3,4-tri-meth-oxy-phen-yl)prop-2-en-1-one.

The title compound, C22H20O5, is composed of a hy-droxy-naphthyl ring and a tri-meth-oxy-phenyl ring [the planes of which are inclined to one another by 21.61 (10)°] bridged by an unsaturated prop-2-en-1-one group. The mean plane of the prop-2-en-1-one group [-C(=O)-C=C-] is inclined to that of the naphthyl system and benzene rings by 3.

Contribution to the knowledge of Tenuibaetis Kang & Yang 1994, Nigrobaetis Novikova & Kluge 1987 and Labiobaetis Novikova & Kluge 1987 (Ephemeroptera: Baetidae) from the Western Ghats (India).

As part of ongoing exploration of the mayflies of hill streams of southern Western Ghats, we describe two new species: Nigrobaetis paramakalyani Kubendran & Balasubramanian n. sp. and Labiobaetis jacobusi Kubendran & Balasubramanian n.

Crystal structure of 4-methyl-N-[2-(piperidin-1-yl)eth-yl]benzamide monohydrate.

In the title compound, C15H22N2O·H2O, the dihedral angle between the planes of the piperidine and benzene rings is 31.63 (1)°. The piperidine ring adopts a chair conformation.

Crystal structure of 3-(4-meth-oxy-phen-yl)-2,3-di-hydro-1H-naphtho-[2,1-b]pyran-1-one.

In the title compound, C20H16O3, the hydro-pyran ring adopts a distorted half-chair conformation with the methine C atom and the ring O atom displaced by -0.554 (2) and 0.158 (1) Å, respectively, from the plane of the other four atoms (r.

Micellar effect on the photophysics of heteroleptic ruthenium(II)-phenanthrolinedisulfonato complexes.

Luminescent heteroleptic ruthenium(II) complexes of type RuLn X(3-n) [L = 1,10-phenanthroline (phen), X = 4,7 diphenyl phenanthroline disulfonate, (dpsphen) n = 0,1,2,3] were synthesized and their photophysical properties investigated in homogeneous and cationic (CTAB), anionic (SDS) and nonionic (Triton X-100) micelles. The luminescent quantum yield and lifetime of the complexes were found to increase in the presence of micellar media and on the introduction of a disulfonate ligand into the coordination sphere. Both electrostatic and hydrophobic interactions play an important role in the micellar media.

Crystal structure of 4-chloro-N-[2-(piperidin-1-yl)eth-yl]benzamide monohydrate.

In the title compound, C14H19ClN2O2·H2O, the piperdine ring adopts a chair conformation. The dihedral angle between the mean plane of the piperidine ring and that of the phenyl ring is 41.64 (1)°.

Crystal structure of 5-(4-benzyl-oxyphen-yl)-3-(4-meth-oxy-phen-yl)-6-methyl-cyclo-hex-2-en-1-one.

The title compound, C27H26O3, crystallized with two independent mol-ecules (A and B) in the asymmetric unit. In mol-ecule A, the plane of the central benzene ring forms dihedral angles of 75.78 (14) and 52.

Crystal structure of (2E)-3-(3-eth-oxy-4-hy-droxy-phen-yl)-1-(4-hy-droxy-phen-yl)prop-2-en-1-one.

In the title compound, C17H16O4, the dihedral angle between the benzene rings is 21.22 (1)° and the mean plane of the prop-2-en-1-one group makes dihedral angles of 10.60 (1) and 11.

Crystal structure of (2E)-1-(4-hy-droxy-3-meth-oxy-phen-yl)-3-(4-hy-droxy-phen-yl)prop-2-en-1-one.

In the title moleclue, C16H14O4, the dihedral angle between the benzene rings is 16.1 (3)°. The meth-oxy group is essentially coplanar with the benzene ring to which it is attached, with a C-O-C C torsion angle of 5.

Crystal structure of 4-methyl-N-{[1-(4-methyl-benzo-yl)piperidin-4-yl]meth-yl}benzamide.

In the title compound, C22H27N2O2, the piperidine ring adopts a half-chair conformation with the benzene rings inclined in a trans orientation with respect to the piperidine ring [dihedral angle between the benzene rings = 89.1 (1)°]. In the crystal, a three-centre asymmetric N-H⋯O/C-H⋯O hydrogen-bonding inter-action leads to the formation of chains extending along the a-axis direction.

Crystal structure of 3-[4-(benz-yloxy)phen-yl]-2,3-di-hydro-1H-benzo[f]chromen-1-one.

In the title compound, C26H20O3, the pyran ring has a distorted half-chair conformation and its mean plane is inclined to the naphthalene ring system, to which it is fused, by 10.79 (9)°. The dihedral angles between the napthalene unit and the benzene and phenyl rings are 54.