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Madonna University[Affiliation] Publications | LitMetric

191 results match your criteria: "Madonna University[Affiliation]"

Introduction/objectives: Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that frequently involves the lungs, contributing to significant morbidity in hospitalized patients. Critical care survivors with lung involvement in SLE are at particularly high risk for unplanned hospital readmissions, which can reflect the complexity of their disease, which often affects multiple organs and requires immunosuppressive therapy that increases infection risk. Severe pulmonary complications, critical illness sequelae, and challenges in medication adherence or follow-up care further contribute to their vulnerability.

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Doxorubicin, as an antibiotic causes toxicity in human tissues through the generation of oxidant species; however, (Solanaceae) is ethnopharmacologically and scientifically reported to possess antidotal activities. This study was designed to validate the antidotal potency of the plant's bioactive compounds on rats' testes following induction with doxorubicin through the evaluation of oxidative stress markers, lipid peroxidation indices, testes' histological sections, and profiling of the plant's bioactive compounds against some proteins. The collection and preparation of the plant extract, testicular toxicity induction, seminal analysis, assay of testosterone and oxidative stress markers, lipid peroxidation profiling, histomorphological studies, retrieval of catalase, superoxide dismutase, and glutathione peroxidase from PDB, GC-MS, ADME, and docking analyses followed standard protocols.

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Article Synopsis
  • Aluminum alloys are popular for their high strength-to-weight ratio, achieved through alloying elements and heat treatments that create intermetallic particles (IMPs) which affect their corrosion resistance.
  • The review focuses on the electrochemical and galvanic corrosion behaviors of various important intermetallic compounds commonly found in aluminum alloys, detailing specific phases like Q-phase, π-phase, and θ-phase.
  • It also addresses limitations in studying these compounds, identifies research gaps, and discusses phenomena such as galvanic polarity reversal and the self-dissolution of IMPs.
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Article Synopsis
  • Obesity is a major public health challenge in the U.S., linked to numerous chronic diseases and increased death rates; this study examines obesity-related deaths from 2010 to 2020 using CDC data.* -
  • The research found a rise in obesity-related mortality rates from 1.8 to 3.1 per 100,000 people over the decade, with older adults, particularly those aged 55-74, showing the highest rates.* -
  • Significant disparities were observed, with males and Black or African American individuals facing higher mortality rates, indicating a need for targeted public health interventions and further research to address obesity management.*
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Article Synopsis
  • Heart failure is a major global health issue, and managing it effectively is crucial for improving patient outcomes and lowering healthcare costs, with ACE inhibitors and ARBs being common treatments.
  • A study using a decision-analytic Markov model aimed to compare the cost-effectiveness of ACE inhibitors and ARBs, considering medical costs and health outcomes for patients with heart failure.
  • Results indicated that ACE inhibitors had lower costs and slightly better health outcomes (quality-adjusted life years) compared to ARBs, with the findings remaining consistent across various sensitivity and subgroup analyses.
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Background: 2,4-Dinitrophenylhydrazine induces testicular toxicity and can result in reproductive dysfunction in male rats.

Aim: This study investigated the effects of hydromethanolic leaf extract of on phenylhydrazine (PHZ)-induced reproductive dysfunction in male Wistar rats.

Settings And Design: Twenty rats (90-170 g) were grouped into five (A-E) ( = 4) with the approval of the research ethics committee.

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Simulation-based training (SBT) has emerged as a transformative approach in medical education, significantly enhancing healthcare professionals' learning experience and clinical competency. This article explores the impact of SBT, tracing its historical development and examining the various types of simulations utilized today, including high-fidelity mannequins, virtual reality environments, standardized patients, and hybrid simulations. These methods offer a safe and controlled environment for students to practice and hone technical and non-technical skills, ultimately improving patient safety and clinical outcomes.

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Introduction: Ambulatory mobility aids are several devices the elderly may use in order to improve their walking pattern, balance, or safety while mobilizing independently.

Objectives: To assess the effect of ambulatory mobility aid devices on cardiovascular parameters, walking speed, perceived exertion, and balance of older adult men.

Methods: A sample of 156 old men was studied.

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Hypertension, a prevalent chronic condition characterized by elevated blood pressure, is a significant global health burden, contributing to approximately 7.5 million premature deaths annually. While existing literature predominantly focuses on conventional treatment modalities, this paper offers unique insights into dependable approaches to hypertension management.

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Defining Nurse Practitioner Core Entrustable Professional Activities: Essential Step Toward Competency-Based Education.

Nurse Educ

August 2024

Conway School of Nursing, The Catholic University of America, Washington, District of Columbia (Dr Moore); College of Nursing and Health, Madonna University, Livonia, Michigan (Dr Chan); College of Nursing, Rush University, Chicago, Illinois (Dr Doucette); School of Nursing, Beal University, Bangor, Maine (Dr Lipps); and Kirkhof College of Nursing, Grand Valley State University, Allendale, Michigan (Dr Slager).

Background: Gaps between educational preparation and clinical practice readiness have led to innovative approaches to competence assessment. Entrustable professional activities (EPAs) show promise as a competence assessment framework in graduate nursing education.

Purpose: This study sought to develop and validate a set of EPAs that reflect the core activities performed by all nurse practitioners (NPs).

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Developments in anticorrosive organic coatings modulated by nano/microcontainers with porous matrices.

Adv Colloid Interface Sci

August 2024

ZJU-UIUC Institute, International Campus, Zhejiang University, Haining 314400, China; Nigerian Alumni Association of the Institute of Metal Research, Chinese Academy of Sciences (NAAIMCAS), Nigeria; Department of Polymer and Textile Engineering, Federal University of Technology, P.M.B. 1526, Owerri, Nigeria.

The durability and functionality of many metallic structures are seriously threatened by corrosion, which makes the development of anticorrosive coatings imperative. This state-of-the-art survey explores the recent developments in the field of anticorrosive organic coatings modulated by innovations involving nano/microcontainers with porous matrices. The integration of these cutting-edge delivery systems seeks to improve the protective properties of coatings by enabling controlled release, extended durability, targeted application of corrosion inhibitors, and can be co-constructed to achieve defect filling by polymeric materials.

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Testing the inhibition efficiency of the castor oil leaf as corrosion inhibitor of mild steel in HSO.

Heliyon

May 2024

Department of Chemical Engineering, Madonna University, Akpugo Campus, 402105, Akpugo, Enugu State, Nigeria.

This study focused on the testing of castor oil leaf as corrosion inhibitor of mild steel in HSO. It involved the examination of the dynamics of molecular forces at the inhibitor and mild steel interface. Findings of the study will promote industrial diversification of castor oil leaf.

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Background: The increasing resistance to most antimalarial drugs suggests a need for better alternatives. This study evaluated in vivo antimalarial and liver antioxidant profile of dry plantain leaf extract (Musa paradisiaca) on mice infected with Plasmodium berghei.

Methods: Six groups of ten mice each grouped as control, P.

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Sexually transmitted diseases (STDs) pose a significant global health challenge with far-reaching social, economic, and public health implications. These infections have haunted humanity from ancient times to today, transcending geographical boundaries and cultural contexts. This article explores the multifaceted landscape of STDs, delving into their epidemiology, pathophysiology, clinical manifestations, and global response strategies.

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Intrauterine adhesions. A sticky problem without a solution.

Fertil Steril

August 2024

Division of Minimally Invasive Gynecologic Surgery, Department of Obstetrics and Gynecology, University of Florida College of Medicine, Gainesville, Florida.

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PAHs are pervasive pollutants known to bioaccumulate in environmental matrices, plants, and humans. Dr. Iguedo Goko Cleanser® is a polyherbal drug with unsubstantiated claims to treat various diseases in sub-Saharan Africa.

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Article Synopsis
  • A thyroid storm is a critical medical emergency caused by extreme hyperthyroidism, requiring quick diagnosis and treatment for survival.
  • This study reviews current diagnostic criteria and scoring systems for thyroid storm, highlighting tools like the Burch-Wartofsky Point Scale, and assesses their effectiveness in identifying cases.
  • The findings indicate that while existing criteria are helpful, they have significant limitations, such as low sensitivity for milder cases and reliance on subjective clinical judgment, suggesting a need for improved, more objective diagnostic methods in the future.
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In healthcare, continuity of care is a crucial element, especially for patients in the field of psychiatry who have recently been discharged from a hospital. The shift from inpatient to outpatient care poses challenges for patients and healthcare providers, including openness to treatment, competing priorities, financial insecurity, concerns and dilemmas faced by patients regarding their post-hospitalization life after improvements in symptoms, lack of social support, poor patient-doctor relationships, lack of insight, and stigma associated with mental illness. Therefore, it is vital to employ effective strategies to ensure patients receive the required care and support during this transition.

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Objective: Social media is becoming recognized as an effective platform for cancer health promotion, education, care, and support. However, its utility as a health promotion tool remains relatively unexplored.

Methods: Using cross-sectional data from the 2017-2020 Health Information National Trends Survey, we evaluated health-related usage of social media among cancer survivors and individuals without a history of cancer.

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Purpose: The incidence of anal cancer is on the rise in the US, especially among high-risk groups. This study examined the prevalence and determinants of awareness of the causal relationship between HPV and anal cancer among US adults.

Methods: Study data was obtained from the 2017 to 2020 iterations of the Health Information National Trends Survey.

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Background: In sub-Saharan Africa, recent graduates from medical school provide more direct surgical and procedural care to patients than their counterparts from the Global North. Nigeria has no nationally representative data on the procedures performed by trainees before graduation from medical school and their confidence in performing these procedures upon graduation has also not been evaluated.

Methods: We performed an internet-based, cross-sectional survey of recent medical school graduates from 15 accredited Federal, State, and private Nigerian medical schools spanning six geopolitical zones.

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