Immunohistochemical analysis of laminin expression in adenoid cystic carcinoma.

Background And Objectives: This study aims at the observation of the immunohistochemical expression of laminin in adenoid cystic carcinoma (ACC) of salivary gland origin and to analyze the distribution of laminin in various components of the tumor and correlate the expression of laminin with the growth and differentiation of the tumor.

Materials And Methods: THIRTY CASES OF ACC WERE SUBJECTED TO IMMUNOHISTOCHEMICAL STUDY USING POLYCLONAL ANTIHUMAN LAMININ PRIMARY ANTIBODY, DISTRIBUTION OF LAMININ IN EACH CASE OF ACC WAS OBSERVED IN THE FOLLOWING AREAS: Intracellularly, inner borders of the pseudocystic spaces, within the lumen of the pseudocysts, around the tumor islands and in the intervening stroma.

Results: Laminin positivity was observed in the inner aspect of the pseudocystic spaces in 15 cases, within the lumen of pseudocystic spaces in 22 cases, in the intervening stroma in 20 cases, bordering the tumor islands in 16 cases and intracellularly in 4 cases.

Modified distal shoe appliance for premature loss of multiple deciduous molars: a case report.

Preservation of the primary dentition until the normal time of exfoliation is one of the most important factor involved in preventive and interceptive dentistry. The premature loss of second primary molar before the eruption of permanent first molar can create a significant arch space/tooth size discrepancy. Distal shoe space maintainer is a valuable part of the Paediatric Dentist's armamentarium in those cases where the second primary molar is prematurely lost and it helps to guide the first permanent molar into place.

Evaluation of smear layer removal from ultrasonically prepared retrocavities by three agents.

Objectives: To evaluate the efficacy of 35% orthophosphoric acid, 24% ethylenediaminetetraacetic acid (EDTA) and 10% citric acid in the removal of smear layer from retrocavities prepared with ultrasonic retro-tips using scanning electron microscopy.

Materials And Methods: Root canals of fifty single-rooted teeth were cleaned, shaped, and obturated with gutta-percha and AH plus sealer. The apical 3 mm of each root was sectioned with a diamond disc and retrograde cavities were prepared with Kis # 1 ultrasonic retro-tips to a depth of 3 mm.

Quantitative analysis of serum levels of trace elements in patients with oral submucous fibrosis and oral squamous cell carcinoma: A randomized cross-sectional study.

Background And Objectives: Metabolic disorders, oral precancerous conditions and oral cancer are accompanied by alterations in the concentration of one or more trace elements like copper, iron, zinc, magnesium etc., in some body fluids, especially blood serum or plasma, which can help not only in the early diagnosis and treatment but also in prognosis. The objective of the study is to evaluate the levels of circulating trace elements (copper, iron, magnesium, zinc and calcium) in serum of patients with Oral Submucous Fibrosis (OSF) and Oral Squamous Cell Carcinoma (OSCC), to analyze the alteration and identify the best predictors amongst these parameters for disease occurrence and progression and their association with areca nut and betel quid chewing habits.

Implant retained auricular prosthesis with a modified hader bar: a case report.

Auricular prostheses for defects of external ear are retained either by mechanical means or implants. All implant retained prostheses are retained by various means such as bar and clip, magnetic attachments or a combination of bar, clip and magnets. The commonest problem encountered with the bar and clip system is loosening of the clip after 3-4 months.

Utilization of free dental health care services provided to the perinatally infected human immunodeficiency virus children in Bangalore: longitudinal study.

Background: Use of Highly active anti-retroviral therapy have increased the life expectancy of human immunodeficiency virus (HIV) infected patients and hence it is imperative that all efforts have to be made by Pediatric dentists to provide a better oral health for these children.

Aim: The aim of this study was to evaluate the rate of utilization of free dental treatment provided to these perinatally infected HIV positive children who were previously screened as a part of oral health survey.

Design: Purposive sampling was used.

Assessment of high-sensitivity C-reactive protein and lipid levels in healthy adults and patients with coronary artery disease, with and without periodontitis--a cross-sectional study.

Background And Objective: Various epidemiological studies have implied that local infection may increase the levels of systemic inflammatory mediators and lipid mediators, thereby promoting atherosclerosis. The aim of this study was to assess high-sensitivity C-reactive protein (HsCRP) and lipid levels in healthy adults and patients with coronary artery disease (CAD), with and without periodontitis.

Material And Methods: A total of 100 subjects were included in the study and categorized into four groups of 25 subjects each, as follows: subjects with chronic periodontitis with angiographically proven CAD; nonperiodontitis subjects with angiographically proven CAD; otherwise healthy subjects with only chronic periodontitis; and systemically and orally healthy individuals.

Lead exposure and its relation to dental caries in children.

Unlabelled: Environmental pollution is a significant health hazard and is mainly caused by commercialization. The etiology of dental caries is multifactorial and one such factor is exposure to trace element such as lead.

Aim: Hence, the present study was carried out to find out the correlation between the levels of lead in the enamel, saliva and dental caries in children.

Moisture-tolerant resin-based sealant: A boon.

Background And Objectives: Pit and fissure sealants are highly effective in preventing occlusal caries. The present study clinically evaluated and compared the retention and development of caries when sealed with moisture-tolerant resin-based sealant, conventional resin-based sealant with and without a bonding agent, and Glass Ionomer Cement Sealant in young permanent teeth.

Materials And Methods: A total of 80 healthy cooperative children aged 6-9 years who were at high caries risk with all four newly erupted permanent first molars were included in the study.

Estimation and comparison of dental, skeletal and chronologic age in Bangalore south school going children.

Objective: Precise evaluation of the developmental stages of a child is an integral part of both diagnosis and treatment planning of pediatric patients and also essential in forensic medicine and dentistry. As human growth shows considerable variation in chronological age, physiological maturity is preferred over chronological age in the estimation of person's exact age.

Materials And Methods: Two hundred and fifty children consisting of 124 girls and 126 boys were selected randomly from the age group of 6-15 years.

Evaluation of tensile strength of surgical synthetic absorbable suture materials: an in vitro study.

Purpose: The purpose of this study was to evaluate the tensile strength of surgical synthetic absorbable sutures over a period of 14 days under simulated oral conditions.

Methods: Three suture materials (polyglycolic acid [PGA], polyglactin [PG] 910, and poly (glycolide-co-є-caprolactone) [PGC]) were used in 4-0 and 5-0 gauges. 210 suture samples (35 of each material and gauge) were used.

Juvenile idiopathic arthritis: review of the literature and case report.

Juvenile idiopathic arthritis (JIA), previously known as juvenile chronic arthritis or juvenile rheumatoid arthritis, is a chronic disease of childhood with a spectrum of joint involvement and associated systemic involvement. The cause of JIA is poorly understood, and no drugs can cure the disease currently. Pediatric dentists should be familiar with the symptoms, complications, and oral manifestations of JIA to help manage the disease and provide quality care to these patients.

Dental subscale of children's fear survey schedule and dental caries prevalence.

Objective: To assess the level of fear of dental procedures among 6-12 year school children and correlate the prevalence of dental caries with their dental fears scores.

Materials And Methods: The study sample of 444 school children, comprising of 224 girls and 220 boys in the age group of 6-12 years old from a private English medium school were selected. Each student was asked to independently complete a Children's Fear Survey Schedule - Dental Subscale (CFSS-DS) questionnaire.

Torus palatinus in an infant: a case report.

The most significant exostoses of the human jaws are the torus palatinus and torus mandibularis. Torus palatinus has long been reported by various anthropological and anatomical studies. Even if it has no functional importance, it could interfere with oral functions.

Influence of restorative technique, Bevelling and aging on composite bonding to sectioned incisal edges: A comparative in vitro study.

Aim: To evaluate the effect of direct and indirect technique, bevel placement, and aging on the fracture resistance of composite restorations bonded to sectioned incisal edges.

Materials And Methods: Incisal thirds of 80 human maxillary incisors were sectioned. Four treatment groups of 20 teeth each were formed as follows: Direct composite with bevel and without bevel (Adper single bond 2/Filtek Z350); indirect composite with bevel and without bevel (prepolymerized Filtek Z350 cemented with Adper single bond 2/Relay × ARC).

Horizontal ridge augmentation using a combination approach.

Resorption of alveolar bone - a common sequel of tooth loss jeopardizes the functional and esthetic outcome of treatment, especially in the maxillary anterior areas. Therefore, augmentation of deficient alveolar ridges is an important aspect of dental implant therapy. A case of severe maxillary ridge deficiency successfully treated with horizontal ridge augmentation to facilitate implant placement is described.

Thesis, antithesis, and synthesis in periodontal and systemic interlink.

The theory of focal infection, which was promulgated during the 19(th) and early 20(th) centuries, stated that "foci" of sepsis were responsible for the initiation and progression of a variety of inflammatory diseases such as arthritis, peptic ulcers, and appendicitis. In the oral cavity, therapeutic edentulation was common as a result of the popularity of the focal infection theory. Since many teeth were extracted without evidence of infection, thereby providing no relief of symptoms, the theory was discredited and largely ignored for many years.

A technique for impressing the severely resorbed mandibular edentulous ridge.

Patients presenting with severe resorption of the residual alveolar ridges are relatively common today in both private practices and teaching institutions. The severely resorbed mandibular ridge is more challenging to impress than is the maxillary ridge. Accurately capturing the denture-bearing surface in its entirety is crucial to providing the patient with a functionally successful prosthesis.

Breastfeeding: Nature's Safety Net.

Breastfeeding is a natural safety-net for the first few months in order to give the child a fairer start to life. The American Academy of Pediatric Dentistry recognizes the distinct nutritional advantages of human milk for infants and endorsed the position of the American Academy of Pediatrics on the promotion of breastfeeding. It therefore calls for increase in need to negotiate the roles and responsibilities of pediatric dentists to eliminate the existing gaps in preventive care and anticipatory guidance.

In vitro assessment of photocatalytic titanium oxide surface modified stainless steel orthodontic brackets for antiadherent and antibacterial properties against Lactobacillus acidophilus.

Objective: To assess the antiadherent and antibacterial properties of surface modified stainless steel orthodontic brackets with photocatalytic titanium oxide (TiO(2)) against Lactobacillus acidophilus.

Materials And Methods: This study was done on 120 specimens of stainless steel preadjusted edgewise appliance (PEA) orthodontic brackets. The specimens were divided into four test groups.

Critical analysis of biomarkers in the current periodontal practice.

Periodontal disease is a chronic microbial infection that triggers inflammation-mediated loss of the periodontal ligament and alveolar bone that supports the teeth. Because of the increasing prevalence and associated comorbidities, there is a need for the development of new diagnostic tests that can detect the presence of active disease, predict future disease progression, and evaluate the response to periodontal therapy, thereby improving the clinical management of periodontal patients. The diagnosis of active phases of periodontal disease and the identification of patients at risk for active disease represent challenges for clinical investigators and practitioners.

Amelogenesis imperfecta: A challenge to restoring esthetics and function.

Rehabilitation of complicated cases poses difficulty in clinical practice, both with respect to restoring function and with esthetics. One such clinical condition where the dentist has to give importance to proper planning of the treatment and execution of the plan is amelogenesis imperfecta (AI), a condition where both function and esthetics are accommodated. This article discusses both the functional and esthetic rehabilitation of a patient with AI.

Prevalence of dental caries and its correlation with the immunologic profile in HIV-Infected children on antiretroviral therapy.

Aim: To describe the prevalence of dental caries in HIV-infected children on antiretroviral therapy. METHODS One hundred and four HIV positive children on antiretroviral therapy, two to fourteen year old children of both sexes were examined for dental caries. Children were divided into three groups based on the dentition: primary, mixed and permanent.

Spectrophotometric analysis on bleaching efficacy of blood stained demineralized and deproteinized dentin--an in vitro study.

Background And Objective: The objectives of this in vitro study, is to evaluate the influence of various dentin treatment procedures prior to bleaching namely, demineralization and demineralization in conjunction with deproteinization on the dentin permeability and bleaching efficacy.

Method: The study used a total of 40 sound premolars, which were sectioned longitudinally, and their color coefficients and absorption spectrum was recorded and used as control values for the later study. These dentin samples were then discolored by blood and their color coefficients and absorption spectrum were calibrated.