Management of first-time patellar dislocation: The ESSKA 2024 formal consensus-Part 2.

Purpose: To provide recommendations for the treatment of patients with first-time patellar dislocation (FTPD). Part 2 focused on nonoperative treatment, bracing, rehabilitation, indications for surgery and surgical strategies.

Methods: The consensus was performed according to the European Society for Sports Traumatology, Knee Surgery and Arthroscopy consensus methodology.

Differential molecular response of larynx cancer cell lines to combined VPA/CDDP treatment.

Successful treatment of advanced larynx squamous cell carcinoma (LSCC) remains a challenge, mainly due to limited response to chemotherapy and the phenomenon of the drug resistance. Therefore, new chemotherapeutic solutions are needed. The aim of this study was to explore benefit of combined cisplatin (CDDP) and valproic acid (VPA) therapy in patients' derived LSCC cell lines.