Midwives' verbal support of nulliparous women in second-stage labor.

Objective: To describe how nurse-midwives verbally support nulliparous women during second-stage labor and document specific details of each second stage.

Design: Descriptive qualitative study.

Setting: A university hospital labor and delivery unit in the southwestern United States.

Hyperglycosylated hCG, hCGβ and Hyperglycosylated hCGβ: interchangeable cancer promoters.

Introduction: Several groups are researching cancers, and showing that hCGβ is a promoter of cancer growth and malignancy. Recent research shows that some hCGβ is present as Hyperglycosylated hCGβ. Other groups studied Hyperglycosylated hCG as a promoter of choriocarcinoma and germ cell malignancies.

Hyperglycosylated hCG, a review.

Hyperglycosylated hCG (hCG-H) is a glycoprotein with the same polypeptide structure as hCG, and much larger N- and O-linked oligosaccharides. The oligosaccharides increase the molecular weight of hCG from 36,000 - 37,000 u to 40,000 - 41,000 u, depending on the extent of hyperglycosylation. hCG-H has triantennary N-linked oligosaccharides and double molecular size O-linked oligosaccharides (hexasaccharide compared with predominantly trisaccharide structures).

Inherited human chorionic gonadotropin.

Objective: To investigate 405 cases of persistent low concentrations of human chorionic gonadotropin (hCG).

Study Design: The USA hCG Reference Service measured total regular hCG, follicle stimulating hormone and luteinizing hormone (LH) with the Siemens (New York, New York) Immulite 1000 assay. Hyperglycosylated hCG, nicked hCG, C-terminal peptide total hCG, intact regular hCG, free beta-subunit and beta-core fragment were measured in manual microtiter plate assays.

Obesity in minority women: calories, commerce, and culture.

Obesity is increasing at epidemic rates in all women, but especially in minority women and children. Factors that contribute to this include changes in caloric intake and expenditure (calories), cost and ease of acquiring food along with pressures from the marketplace and media (commerce) and the community response to the increasing prevalence of obesity and sedentary lifestyle (culture).

Does spontaneous genital tract trauma impact postpartum sexual function?

Changes in sexual function are common in postpartum women. In this comparative, descriptive study, a prospective cohort of midwifery patients consented to documentation of genital trauma at birth and assessment of sexual function at 3 months postpartum. The impact of spontaneous genital trauma on postpartum sexual function was the focus of the study.

Cervical cancer screening in the early post vaccine era.

The Pap test is the foundation of cervical cancer screening in North America and most industrialized countries. It has been widely used in the United States since the 1950s. But are our current screening guidelines still justified? In this article, the author reviews the current recommendations for cervical cancer screening by the American Cancer Society (ACS) and the American College of Obstetricians and Gynecologists (ACOG) and the evidence supporting them, reviews the relative efficacy of liquid-based cytology versus the conventional Pap smear, and discusses the role of HPV DNA testing in primary screening.

Efficacy of tolterodine on overactive bladder symptoms and sexual and emotional quality of life in sexually active women.

We evaluated overactive bladder (OAB) symptoms and sexual and emotional health in sexually active women with OAB/urgency urinary incontinence (UUI) treated with tolterodine extended release (ER). Sexually active women with OAB symptoms were randomized to placebo or tolterodine ER. Five-day bladder diaries, Sexual Quality of Life Questionnaire-Female (SQOL-F), Pelvic Organ Prolapse/Urinary Incontinence Sexual Questionnaire (PISQ), and Hospital Anxiety and Depression Scale (HAD) were completed at baseline and week 12.

Hyperglycosylated hCG.

Hyperglycosylated hCG (hCG-H) is a glycosylation variant of the hormone hCG. Here we review all that is known about this independently functioning molecule. As discussed, it is a very different molecule to the hormone hCG.

Postpartum genitourinary changes.

Genitourinary changes following childbirth and pregnancy are common, and include urinary and anal incontinence, pelvic pain, sexual dysfunction, and pelvic organ prolapse. At present, it is unclear whether or not these changes are a result of the pregnancy itself or the mode of delivery (cesarean section or vaginal birth). In this article, the authors aim to describe genitourinary postpartum pelvic floor changes, and review the literature regarding the impact of pregnancy or childbirth on these changes.

Teaching and evaluating ultrasound skill attainment: competency-based resident ultrasound training for AIUM accreditation.

Modern obstetrics and gynecology practice requires the frequent use of ultrasound and ultrasound training as a required component of obstetrics and gynecology residencies. Although programs do offer training in obstetric ultrasound imaging, education in gynecologic imaging is either absent or limited. This article describes a comprehensive ultrasound curriculum for obstetrics and gynecology residents that has been developed and implemented at the University of New Mexico.

Mental practice and acquisition of motor skills: examples from sports training and surgical education.

Learning surgical skills involves both fine and gross motor skills, and necessitates performance in stressful situations. This environment is similar to the environment in which an athlete performs. Mental imagery has been used successfully in training athletes of all levels of proficiency and enhances both motor skills and motivational skills of performing under stress.

Gestational trophoblastic diseases: 1. Pathophysiology of hyperglycosylated hCG.

Objective: Hyperglycosylated hCG (hCG-H) is a glycosylation variant of hCG produced by cytotrophoblast cells at implantation of pregnancy and in choriocarcinoma. We investigated the biological function of hCG-H in invasion in vitro and in vivo and the use of hCG-H antibodies in blocking tumorigenesis and cancer growth in vivo.

Methods And Results: hCG-H accounts for 43% to 100% of total hCG immunoreactivity in the culture fluid of choriocarcinoma cell lines and 100% in primary cultures of pregnancy cytotrophoblast cells.

Gestational trophoblastic diseases: 4. Presentation with persistent low positive human chorionic gonadotropin test results.

Objectives: A high proportion of women with persistent low levels of hCG, in the absence of pregnancy or any evidence of tumor, have received chemotherapy and hysterectomy for assumed malignancy. Such chemotherapy and surgery were ineffective and unwarranted. This study identifies the causes of persistent low level of hCG and provides guidelines for the management of these patients, preventing unnecessary treatment in the future.