95 results match your criteria: "MRSA Skin Infection in Athletes"
Rapidly in situ forming antibiotic-free injectable hydrogel wound dressing for eradicating drug-resistant bacterial infections in human skin organoids.
Int J Biol Macromol
December 2024
Senior Department of Orthopedics, The Fourth Medical Center of PLA General Hospital, Beijing 100091, China. Electronic address:
The rising prevalence of global antibiotic resistance evokes the urgent requirement to explore the alternative antimicrobial candidates. It is of great significance to overcome these serious threats of multidrug-resistant bacterial infections and difficult-to-heal cutaneous wounds to human health. Herein, we proposed a rapidly in situ forming innovative antibiotic-free hydrogel dressing with excellent biocompatibility, easy injectability, strong tissue adhesion and superior antibacterial activity against drug-resistant bacteria.
View Article and Find Full Text PDFThe two-component regulatory systems GraRS and SrrAB mediate susceptibility to Pep5 produced by clinical isolate of .
Appl Environ Microbiol
July 2024
Department of Bacteriology, Hiroshima University Graduate School of Biomedical and Health Sciences, Hiroshima, Japan.
Article Synopsis
- KSE112, a clinical strain of Staphylococcus aureus, produces the lantibiotic Pep5, which has potential as an antimicrobial agent against severe infections.
- The study involved determining the complete nucleotide sequence of the Pep5-encoding plasmid and assessing the effects of two-component regulatory systems (TCSs) on Pep5 susceptibility, revealing that inactivation of certain TCS mutants altered susceptibility levels.
- Findings suggest that reduced aerobic respiration affects Pep5 effectiveness, highlighting the need for novel antimicrobial strategies to combat drug-resistant bacteria like MRSA.
Article Synopsis
- Outbreaks of PVL-producing MRSA skin infections among Royal Marines at their training center have been a persistent issue, linked to intense training and skin injuries.
- The study aimed to address these infections by using extra swabs on cuts and enhancing a 10-day decolonization program, leading to better identification and management of MRSA carriers.
- During the outbreak, 18 out of 36 recruits developed infections, but strengthened infection control measures effectively contained the outbreak to one troop, reducing further spread.
Cross-sectional study of the association of social relationship resources with Staphylococcus aureus colonization in naturally occurring social groups along the US/Mexico border.
PLoS One
April 2023
Center for Health Equity Research, Northern Arizona University, Flagstaff, AZ, United States of America.
Article Synopsis
- * In a sample of 443 community members in southwestern Arizona, no significant link was found between the number/diversity of social contacts and S. aureus colonization rates, which stood at 64.8%.
- * The findings suggest that social network diversity does not protect against S. aureus, indicating that more personal interactions may be more relevant for its transmission within the community.
"Recommendations for periprosthetic joint infections (PJI) prevention: the European Knee Associates (EKA)-International Committee American Association of Hip and Knee Surgeons (AAHKS)-Arthroplasty Society in Asia (ASIA) survey of members".
Knee Surg Sports Traumatol Arthrosc
December 2022
Department of Orthopaedic Surgery and Traumatology, Kantonsspital Baselland (Bruderholz, Liestal, 4101, Bruderholz, Laufen), Switzerland.
Article Synopsis
- Periprosthetic joint infections (PJIs) are serious complications arising from total joint replacement surgeries, prompting a study by major orthopedic associations to understand prevention strategies among surgeons.
- An online survey targeting surgeons from Europe, the Americas, and Asia gathered data on PJI prevention measures during preoperative, intraoperative, and postoperative phases, covering aspects like risk assessment and antibiotic use.
- Out of 394 participating surgeons, results showed varied practices, such as only 40.6% applying PJI risk thresholds preoperatively, and 43.4% administering a single antibiotic for high-risk patients during surgery, highlighting inconsistent adherence to preventive measures.
Local Application of Vancomycin in One-Stage Revision of Prosthetic Joint Infection Caused by Methicillin-Resistant Staphylococcus aureus.
Antimicrob Agents Chemother
August 2021
Department of Joint Surgery and Sports Medicine, Zhongnan Hospital of Wuhan Universitygrid.413247.7, Wuhan, China.
Article Synopsis
- The study investigates the effectiveness of intraarticular (IA) vancomycin injections for treating methicillin-resistant Staphylococcus aureus (MRSA) periprosthetic joint infections (PJI) after one-stage revision surgery in rats.
- Results showed that IA injection improved health indicators like skin temperature and inflammatory response compared to systemic (intraperitoneal) vancomycin alone.
- The combination of both IA and systemic vancomycin provided the best results, and although IA treatment alone didn't eradicate MRSA, it was deemed safe and more effective than just systemic administration.
2021 Chitranjan S. Ranawat Award: Intraosseous vancomycin reduces periprosthetic joint infection in primary total knee arthroplasty at 90-day follow-up.
Bone Joint J
June 2021
Department of Orthopedics and Sports Medicine, Houston Methodist Hospital, Houston, Texas, USA.
Article Synopsis
- - The study reviews the incidence of periprosthetic joint infections (PJI) in total knee arthroplasties (TKA), focusing on the effectiveness of intravenous (IV) vs. intraosseous (IO) administering of vancomycin, particularly in relation to methicillin-resistant Staphylococcus aureus (MRSA) concerns.
- - A total of 1,060 patients were analyzed, with results indicating a significantly lower infection rate in the IO group (0.22%) compared to the IV group (1.4%) over at least 90 days.
- - The findings suggest that using IO vancomycin, paired with a first-generation cephalosporin, may reduce infection rates in
First Report of Fatal Infection Caused by Community-acquired Methicillin-resistant USA300 Clone in a Collegiate Athlete.
JMA J
January 2020
Emergency and Critical Care Medicine, Tokyo Medical University Hachioji Medical Center, Tokyo, Japan.
Article Synopsis
- Community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) is becoming more common globally and can lead to serious skin and soft tissue infections in otherwise healthy people.
- Panton-Valentine leukocidin (PVL)-positive CA-MRSA strains, while rare in Japan, have the potential to cause severe conditions like septic pulmonary emboli and infectious endocarditis.
- This study highlights a significant case of a 20-year-old Japanese college athlete who faced a life-threatening infection from a PVL-positive CA-MRSA strain, presenting with multiple severe complications including sepsis and deep vein thrombosis.
Outbreak of community-acquired Staphylococcus aureus skin infections in an Australian professional football team.
J Sci Med Sport
June 2021
Susan Wakil School of Nursing and Midwifery, Faculty of Medicine and Health, The University of Sydney, Australia; Marie Bashir Institute for Infectious Diseases and Biosecurity, The University of Sydney, Australia.
Article Synopsis
- * Almost 49% of team members were found to be carriers of MSSA, with a specific cluster of MRSA identified among four players, highlighting serious transmission issues.
- * The outbreak was linked to poor hygiene practices in team facilities, emphasizing the need for better hygiene education and strict adherence to cleaning protocols to prevent future infections.
Methicillin-Resistant : Risk for General Infection and Endocarditis Among Athletes.
Antibiotics (Basel)
June 2020
Department of Molecular Medicine and Medical Biotechnology, University of Naples Federico II, Via S.Pansini 5, 80131 Naples, Italy.
Article Synopsis
- * Recent research using molecular epidemiology has revealed how prolonged contact and sweating among athletes contribute to the transmission of SA infections.
- * The review highlights current SA infection knowledge, diagnostic methods, and emphasizes the importance of preventive strategies to limit its spread in sports environments.
A risk as an infection route: Nasal colonization of methicillin-resistant Staphylococcus aureus USA300 clone among contact sport athletes in Japan.
J Infect Chemother
August 2020
Emergency and Critical Care Medicine, Tokyo Medical University Hachioji Medical Center, 1163 Tatemachi, Hachioji, Tokyo 193-0998, Japan.
Article Synopsis
- The Panton-Valentine leukocidin (PVL)-positive USA300 clone is a dangerous strain of methicillin-resistant Staphylococcus aureus (MRSA) that commonly affects athletes due to their high risk of skin injuries and close interactions.* -
- A case study involved a Japanese collegiate football player who developed serious lung infections from this strain after having deep vein thrombosis, prompting researchers to investigate how teammates might also be carrying the bacteria.* -
- Screening revealed that 5.8% of the nasal samples from teammates tested positive for CA-MRSA, with some showing a direct genetic link to the infected player, highlighting the need for better infection control measures in contact sports to prevent outbreaks.*
Community-associated Methicillin-Resistant Staphylococcus aureus Infection Rates and Management among Student-Athletes.
Med Sci Sports Exerc
September 2018
Misericordia University, Dallas, PA.
Article Synopsis
- CA-MRSA infections in athletics show variability, with higher incidence rates in sports like wrestling and football; 26.8 cases per 10,000 athletes in 2015-2016 and 20.3 in 2016-2017.
- Surveys revealed that around 23-39% of athletic trainers reported physician-confirmed CA-MRSA infections among athletes, highlighting a significant concern.
- Management strategies primarily included athlete education and environmental decontamination, indicating a need for ongoing educational efforts to further reduce infection rates.
Methicillin resistant Staphylococcus Aureus in emergency department patients in the United Arab Emirates.
BMC Emerg Med
May 2018
Department of Emergency Medicine, Brigham & Women's Hospital, Boston, USA.
Article Synopsis
- Community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) has become a significant cause of skin and soft tissue infections worldwide, yet its prevalence in the Middle East is not well understood.
- A study conducted in Dubai involved 100 emergency department patients with purulent infections, revealing a 23% prevalence of MRSA among culture-positive cases and identifying contact sports and female sex as independent risk factors.
- The findings highlight a considerable number of infections attributable to CA-MRSA, suggesting that while incision and drainage are essential for treatment, appropriate antibiotics targeting CA-MRSA should be considered when necessary.
Recommendations for Best Disinfectant Practices to Reduce the Spread of Infection via Wrestling Mats.
J Athl Train
February 2017
Department of Human Performance and Sports Sciences, Ohio Northern University, Ada.
Article Synopsis
- A study commissioned by the National Wrestling Coaches Association analyzed infection transmission among collegiate wrestlers, focusing on the effectiveness of various disinfectants for wrestling mats.
- The research involved both a laboratory setting, testing disinfectants like bleach and OxiTitan against bacterial loads, and empirical testing during two wrestling meets where mat and wrestler bacteria were monitored.
- Results indicated that disinfectants with claimed residual activity significantly reduced bacterial load, and only a small number of wrestlers tested positive for methicillin-resistant Staphylococcus aureus, while skin and respiratory bacteria were predominantly found on the mats.
Cellulitis: A Review.
JAMA
July 2016
Harvard Medical School, Massachusetts General Hospital, Boston.
Article Synopsis
- Cellulitis is a common infection in the skin's deeper layers, leading to symptoms like redness, warmth, and swelling, with over 650,000 hospital admissions annually in the U.S.
- It costs about $3.7 billion in outpatient care each year, but most cases can't identify the specific bacteria causing the infection; when identified, they are mainly from β-hemolytic Streptococcus and Staphylococcus aureus.
- Effective treatment focuses on these bacteria, especially in at-risk groups, with a typical five-day course, while diagnosis relies heavily on clinical evaluation rather than precise testing.
Article Synopsis
- The text discusses a specialized program in the Czech Republic for treating patients with giant complex ventral hernias, emphasizing a high-volume hernia center since 2012.
- From 2012 to 2015, 36 patients were treated using various advanced surgical techniques and emphasized the importance of comprehensive preoperative planning and postoperative care.
- The program is challenging due to its complexity, high costs, and potential for complications, but aims to improve the quality of life for patients with severe health and social issues.
Longitudinal Assessment of Colonization With Staphylococcus aureus in Healthy Collegiate Athletes.
J Pediatric Infect Dis Soc
June 2016
Division of Pediatric Infectious Diseases.
Article Synopsis
- Staphylococcus aureus is a major cause of infections in the U.S. and athletes are at higher risk due to colonization; this study aimed to investigate colonization rates among varsity athletes.
- A study of 377 athletes revealed S. aureus colonization rates between 34% and 62%, with higher rates in summer (notably for MRSA) and identified key genetic markers in the MRSA isolates.
- The findings suggest that seasonal variations in colonization may influence infection rates, indicating the need for preventive measures, particularly during summer when risks are heightened.
Colonization With Methicillin-resistant Staphylococcus aureus and Risk for Infection Among Asymptomatic Athletes: A Systematic Review and Metaanalysis.
Clin Infect Dis
July 2016
Infectious Diseases Division, Warren Alpert Medical School of Brown University, Rhode Island Hospital, Providence.
Article Synopsis
- * The USA300 strain is commonly found, with many strains showing resistance to key antibiotics, raising concerns about treatment options.
- * MRSA colonization increases the risk of subsequent infections by over seven times, highlighting the urgent need for better infection control measures and decolonization strategies in athletic environments.
CA-MRSA Infection Incidence and Care in High School and Intercollegiate Athletics.
Med Sci Sports Exerc
August 2016
1Rocky Mountain University of Health Professions, Provo, UT; 2Idaho State University, Pocatello, ID; 3Misericordia University, Dallas, PA; 4Indiana State University, Terre Haute, IN; 5University of Indianapolis, Indianapolis, IN.
Purpose: Position papers offer solutions to manage community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA), yet few studies establish the infection rate, management protocols, and referral practices among student-athletes. Over the 2012-2013 and 2013-2014 school years, we assessed the annual CA-MRSA infection incidence, sport risk, referral practices, and management steps among high school and intercollegiate athletics.
Methods: This study targeted high school and intercollegiate athletic programs in the Northeastern United States.
Bacterial Skin Infections.
Prim Care
December 2015
Family Medicine and Sports Medicine, Department of Family Medicine, Mayo Clinic, 4500 San Pablo Road, Jacksonville, FL 32224, USA.
Article Synopsis
- Skin and soft tissue infections make up 0.5% of visits to primary care, and are often manageable in an outpatient setting.
- Certain situations, however, may require urgent or inpatient care, as discussed in the article.
- The article serves as a guide for family physicians on how to assess, manage, and follow up on common bacterial skin infections.
Article Synopsis
- Skin infections are a significant issue among athletes, particularly wrestlers, who face an 8.5% incidence of such infections due to close physical contact during matches and practices.
- Common skin infections among high school wrestlers include fungal infections like ringworm, viral infections such as herpes gladiatorum, and bacterial infections including those caused by MRSA.
- In response to an outbreak following a wrestling tournament where wrestlers reported skin lesions, Maricopa County Public Health launched an investigation to understand the infection's causes and recommend prevention strategies.
Staphylococcus aureus and community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) in and around therapeutic whirlpools in college athletic training rooms.
J Athl Train
April 2015
Indiana State University, Terre Haute. Dr Kahanov is now at College of Health Sciences, Misericordia University, Dallas, PA. Young Kyun Kim, MA, is now at Moungji University, Yong-in, South Korea.
Article Synopsis
- Community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) is common in athletic training rooms and can lead to skin infections in athletes.
- A study at a Division I university examined the levels of Staphylococcus aureus and CA-MRSA in whirlpools used by athletes, finding Staphylococcus aureus in 22% of samples but CA-MRSA in only 0.8%.
- The research indicated that the presence of Staphylococcus aureus in these facilities was significant, and adhering to proper cleaning protocols could help minimize bacterial transmission among athletes.
Staphylococcus aureus skin infection recurrences among household members: an examination of host, behavioral, and pathogen-level predictors.
Clin Infect Dis
March 2015
Section of Infectious Diseases, Department of Pediatrics, University of Chicago, Illinois.
Article Synopsis
- A study investigated factors that predict recurrent Staphylococcus aureus infections among treated patients and their household contacts in Los Angeles and Chicago, involving surveys and follow-ups at 3 and 6 months.
- The results revealed that 51% of patients experienced recurrence by month 6, with significant association to factors like recent hospitalization, fomite contamination at home, and absence of recent contact sports.
- The findings suggest that decontaminating household items may help reduce the risk of recurrence in patients suffering from S. aureus skin infections.
Article Synopsis
- The study aimed to evaluate staphylococcal carriage, including MRSA, among nursing students at Texas State University over clinical semester rotations from 2010 to 2012, identifying risk factors associated with colonization.
- A total of 87 nursing students participated, with interventions including nasal decolonization treatment and oral antibiotics; follow-ups were conducted to ensure decolonization before subsequent clinical rotations.
- Results showed that MRSA colonization levels remained stable, while the incidence of Staphylococcus aureus was between 17.7% and 26.4%, with significant associations found between non-S. aureus species and healthcare or gym exposure.
Skin infections caused by community-acquired methicillin-resistant Staphylococcus aureus: clinical and microbiological characteristics of 11 cases.
Actas Dermosifiliogr
March 2014
Servicio de Dermatología, Hospital General Universitario Gregorio Marañón, Madrid, España.
Article Synopsis
- CA-MRSA is a growing concern as it leads to skin and soft-tissue infections, particularly affecting healthy young individuals outside of healthcare settings.
- A study involving 11 patients revealed that the typical manifestation is a skin abscess with significant tissue damage and minimal pus, often occurring in those under 40 years old.
- Effective treatment requires surgical drainage of the abscess, and it's important to avoid β-lactam antibiotics due to prior ineffectiveness in many cases.*