265,664 results match your criteria: "MN & Ridgeview Medical Center[Affiliation]"

Tracking biodiversity across biomes over space and time has emerged as an imperative in unified global efforts to manage our living planet for a sustainable future for humanity. We harness the National Ecological Observatory Network to develop routines using airborne spectroscopic imagery to predict multiple dimensions of plant biodiversity at continental scale across biomes in the US. Our findings show strong and positive associations between diversity metrics based on spectral species and ground-based plant species richness and other dimensions of plant diversity, whereas metrics based on distance matrices did not.

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Endoplasmic Reticulum-Targeted Polymer-Manganese Nanocomplexes for Tumor Immunotherapy.

ACS Nano

January 2025

Key Laboratory of Integrated Oncology and Intelligent Medicine of Zhejiang Province, Affiliated Hangzhou First People's Hospital, School of Medicine, Westlake University, Hangzhou 310006, China.

Manganese ions (Mn) are an immune activator that enhances the activation of both cGAS and STING proteins. The STING signaling activation and subsequential immune responses are predominantly associated with endoplasmic reticulum (ER). Therefore, ER targeting of Mn in the subcellular compartments would promote the activation of STING signaling pathways.

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Exploring Health Educational Interventions for Children With Congenital Heart Disease: Scoping Review.

JMIR Pediatr Parent

January 2025

Department of Design Innovation, College of Design, University of Minnesota, Twin Cities, Minneapolis, MN, United States.

Background: Congenital heart disease (CHD) is the most common birth defect, affecting 40,000 births annually in the United States. Despite advances in medical care, CHD is often a chronic condition requiring continuous management and education. Effective care management depends on children's understanding of their condition.

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Degradation of Methylene Blue by Ozone Oxidation Catalyzed by the Magnetic MnFeO@CoS Nanocomposite.

Langmuir

January 2025

CSSC Nanjing Lvzhou Environmental Protection Co., Ltd, Nanjing 210039, China.

In this study, the MnFeO@CoS magnetic nanocomposite was prepared by a two-step hydrothermal method and used to catalyze the ozone oxidation degradation of methylene blue. It was characterized by XRD, EDS, SEM, FT-IR, and XPS. The results showed that the introduction of CoS made MnFeO grow uniformly on CoS nanosheets, which effectively prevented the agglomeration of MnFeO.

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This current study focusses on the investigation of the self-healing abilities of metallopolymers containing different kinds of metal complexes, which were processed by direct digital light processing (DLP) based three-dimensional (3D) printing. For this purpose, 2‑phenoxyethyl acrylate is mixed with ligand-containing monomers either based on triphenylmethyl(trt)-histidine or terpyridine, respectively. Either zinc(II) or nickel(II) salts are successfully applied for a complexation of the ligand monomers in solution and, subsequently, photopolymerization is performed.

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Background: The reported benefit of poly (ADP-ribose) polymerase inhibitor (PARPi) maintenance in patients with newly diagnosed and platinum (Pt)-sensitive recurrent ovarian cancer (OC) included in randomized clinical trials needs to be corroborated in a less selected population.

Objective: The aim is to increase the evidence on niraparib in a real-world setting.

Methods: This is a retrospective observational study including women with platinum-sensitive relapsed high-grade serous OC who started niraparib maintenance between August 2019 (marketing data, Spain) and May 2022.

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Clinical Diagnosis and Differential Diagnosis Between CSF1R- and AARS2-Related Leukoencephalopathy.

J Mol Neurosci

January 2025

Department of Neurology, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Science/Peking Union Medical College, Beijing, 100730, China.

CSF1R-related leukoencephalopathy (CSF1R-L) and AARS2-related leukoencephalopathy (AARS2-L) were two disease entities sharing similar phenotype and even pathological changes. Although clinically, radiologically, and pathologically similar, they were caused by mutation of two different genes. As the rarity of the two diseases, the differential diagnosis of them was difficult.

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Pollinators help maintain functional landscapes and are sensitive to floral nutritional quality. Both proteins and lipids influence pollinator foraging, but the role of individual biochemical components in pollen remains unclear. We conducted an experiment comprising common garden plots of six plant species (Asteraceae, Rosaceae, Onagraceae, Boraginaceae, and Plantaginaceae).

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Purpose: The brown marmorated stink bug, Halyomorpha halys (Hemiptera: Pentatomidae), is an invasive and a highly polyphagous species with a strong dispersal capacity. Unfortunately, there is currently no effective control method that can prevent or reduce the economic loss caused by this pest. Among natural enemies, microsporidia cause infections in insects so that they can generally shorten life span, reduce fertility and inhibit growth.

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Background: Electroconvulsive therapy (ECT) is an effective treatment for treatment-resistant depression (TRD). There are limited data on the improvement of anxiety symptoms in patients receiving ECT for TRD.

Objective: The aim of the study was to examine the extent to which anxiety symptom severity improves, relative to improvements in depressive symptoms, in TRD patients receiving an acute course of ECT.

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Electroconvulsive therapy (ECT) is an effective treatment for severe depression, especially in treatment-resistant cases. However, its potential cognitive side effects necessitate careful dosing to balance therapeutic benefits and cognitive stability. Recent advances in electric field (E-field) modeling offer promising avenues to optimize ECT dosing.

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Circulating and Magnetic Resonance Imaging Biomarkers of Intestinal Fibrosis in Small Bowel Crohn's Disease.

Inflamm Bowel Dis

January 2025

Division of Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH, USA.

Background: We previously identified circulating and MRI biomarkers associated with the surgical management of Crohn's disease (CD). Here we tested associations between these biomarkers and ileal resection inflammation and collagen content.

Methods: Fifty CD patients undergoing ileal resection were prospectively enrolled at 4 centers.

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Heavy metal pollution in agricultural soils poses a serious threat to food security. Therefore, it is crucial to conduct risk assessments and issue early warnings about high levels of metal contamination for the sustained prosperity of agriculture. To assess the risks, identify the sources, quantify the amounts, and determine the extent of pollution from seven heavy metals, as well as to provide early warnings, 78 soil samples were collected from farmed lands in the Songnen Plain of Jilin Province.

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Prenatal lead (Pb) and manganese (Mn) exposure can impair neurodevelopment, targeting the central nervous system. This study investigated the effects of prenatal exposure to Pb and Mn on neurodevelopment in children at 18 months of age, using data from 607 Italian mother-child pairs enrolled in the Northern Adriatic Cohort II (NAC-II). All children born at term (≥37 weeks) were assessed with the Bayley Scales of Infant and Toddler Development, third edition.

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Assessing Pollution with Heavy Metals and Its Impact on Population Health.

Toxics

January 2025

Department of Civil Engineering, Transilvania University of Brașov, 5 Turnului Str., 500152 Brașov, Romania.

Pollution is one of the most important issues currently affecting the global population and environment. Therefore, determining the zones where stringent measures should be taken is necessary. In this study, Principal Component Analysis (PCA), Factor Analysis (FA), and t-distributed Stochastic Neighbor Embedding (t-SNE) were utilized for dimensionality reduction and clustering of data series containing the concentration of 10 heavy metals collected at 14 locations.

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Heterocyclic aromatic amines (HAAs), formed during the cooking of meat, are potential human carcinogens, underscoring the need for long-lived biomarkers to assess exposure and cancer risk. Frequent consumption of well-done meats containing 2-amino-1-methyl-6-phenylimidazo[4,5-]pyridine (PhIP), a prevalent HAA that is a prostatic carcinogen in rodents and DNA-damaging agent in human prostate cells, has been linked to aggressive prostate cancer (PC) pathology. African American (AA) men face nearly twice the risk for developing and dying from PC compared to White men.

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Particle Size-Dependent Monthly Variation of Pollution Load, Ecological Risk, and Sources of Heavy Metals in Road Dust in Beijing, China.

Toxics

January 2025

Beijing Key Laboratory of Resource-Oriented Treatment of Industrial Pollutants, School of Energy and Environmental Engineering, University of Science and Technology Beijing, Beijing 100083, China.

Road dust carries various contaminants and causes urban non-point source pollution in waterbodies through runoff. Road dust samples were collected in each month in two years and then sieved into five particle size fractions. The concentrations of ten heavy metals (As, Cd, Cr, Cu, Hg, Mn, Ni, Pb, Zn, Fe) in each fraction were measured.

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There is concern over potential toxic elements (PTEs) impacting river ecosystems due to human and industrial activities. The river's water, sediment, and aquatic life are all severely affected by the release of chemical and urban waste. PTE concentrations in sediment, water, and aquatic species from river ecosystems are reported in this review.

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Environmental pollutants significantly impact health and quality of life. High levels of harmful metals in drinking water, vegetables, and soil can accumulate in the body, leading to serious health issues. In Gilgit-Baltistan, Pakistan, the prevalence of cancer is notably high, and heavy metals are considered among the possible risk factors.

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Heat stress (HS) induced by global warming is a real welfare, productivity, and economic burden of cattle production. However, some cattle breeds have superior physiological adaptive traits to others, yet the underlying molecular mechanisms are not fully defined. The present study aimed, therefore, to determine the expression profile of stress-related molecular signatures in the blood of thermosensitive Angus () and thermotolerant Brahman () cattle breeds managed without (CON) or with growth-promoting technology (TRT) during the summer (April-October, 2023) season in Colorado, US.

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Negative Association of Gulf War Illness Symptomatology with Predicted Binding Affinity of Anthrax Vaccine Antigen to Human Leukocyte (HLA) Class II Molecules.

Vaccines (Basel)

January 2025

The GWI and HLA Research Groups, Brain Sciences Center, Department of Veterans Affairs Health Care System, Minneapolis, MN 55417, USA.

Background: Anthrax is a serious disease caused by () with a very high mortality when the spores of are inhaled (inhalational anthrax). Aerosolized spores can be used as a deadly bioweapon. Vaccination against anthrax is the only effective preventive measure and, hence, the anthrax vaccine was administered to United States (and other) troops during the 1990-91 Gulf War.

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Controllable Nano-Crystallization in Fluoroborosilicate Glass Ceramics for Broadband Visible Photoluminescence.

Nanomaterials (Basel)

January 2025

Sino-French Hoffmann Institute, School of Basic Medical Science, Guangzhou Medical University, Guangzhou 511436, China.

A transparent fluoroborosilicate glass ceramic was designed for the controllable precipitation of fluoride nanocrystals and to greatly enhance the photoluminescence of active ions. Through the introduction of BO into fluorosilicate glass, the melting temperature was decreased from 1400 to 1050 °C, and the abnormal crystallization in the fabrication process of fluorosilicate glass was avoided. More importantly, the controlled crystallizations of KZnF and KYbF in fluoroborosilicate glass ceramics enhanced the emission of Mn and Mn-Yb dimers by 6.

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In this work, a series of BaMnCuO samples (x: 1, 0.9, 0.8, and 0.

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This commentary examines Topological Data Analysis (TDA) in radiology imaging, highlighting its revolutionary potential in medical image interpretation. TDA, which is grounded in mathematical topology, provides novel insights into complex, high-dimensional radiological data through persistent homology and topological features. We explore TDA's applications across medical imaging domains, including tumor characterization, cardiovascular imaging, and COVID-19 detection, where it demonstrates 15-20% improvements over traditional methods.

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Biochemical Composition and Seasonal Variations of the Madagascar Algae (, Rhodophyta).

Mar Drugs

January 2025

Laboratoire de Biotechnologie et Chimie Marines (LBCM), EMR CNRS 6076, IUEM, Université Bretagne Sud, Campus Tohannic, 56000 Vannes, France.

Although the density and diversity of seaweeds in Madagascar is particularly high, these resources are underexploited and they are not part of the local population's eating habits. No study has been carried out on the nutritional properties and seasonal variation of species harvested in Madagascar. In this study, was harvested monthly over two years (2021 and 2022) on the northeast coast of Madagascar (Sainte Marie Island).

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