Designing, Validation, and Feasibility of Integrated Approach of Heartfulness Meditation and Yoga Protocol (IAHFNM & YP) for Hypertensive Participants.

The module was designed and developed at Heartfulness Institute, Kanha Shanti Vanam, Hyderabad. The Department of Medicine, MGM Medical College & Hospital, MGMIHS, Navi Mumbai, carried out the validation and subsequently pilot-tested on volunteers. Forty experts were selected to validate the contents of IAHFNM & YP which was designed after a thorough review of meditation and yoga literature.

A Secondary Analysis of the Prevalence and Clinical Profile of Psychiatric Referrals of Delirium in a Tertiary Care Hospital in Central India.

Introduction: Delirium is a common and serious neuropsychiatric syndrome characterized by acute, fluctuating alterations in consciousness, cognition, and perception. It is associated with increased morbidity, mortality, length of hospital stays, and healthcare costs.

Aim:  The aim of this study was to assess the prevalence and clinical profile of psychiatric referrals of delirium in a tertiary-care hospital.

Managing Hereditary Angioedema in a Three-Generation Family: Danazol's Promise in Resource-Limited Settings.

Background Hereditary angioedema (HAE) is a rare disorder in India, and while prevalence data is limited, it is believed that a significant number of individuals may be affected. Due to restricted access to first-line treatments, older therapies like danazol are commonly used despite associated risks in resource-constrained settings. This study aimed to assess the efficacy of danazol as an affordable long-term prophylaxis (LTP) for HAE in a three-generation family.

Ultrasonography- and Fluoroscopy-Guided Technique for Cooled Radiofrequency Ablation of the Genicular Nerves for Knee Joint Pain.

Knee osteoarthritis is a chronic degenerative disease associated with pain and decreased mobility that affects advanced-age individuals, thus causing further debilitation. Radiofrequency ablation can benefit patients who are not ideal candidates for surgical intervention and for whom conservative management has been unsatisfactory. Currently, radiofrequency ablation is performed using either ultrasonography or fluoroscopy.

The Role of Telemedicine in Enhancing Surgical Care Delivery in Africa: A Literature Review.

Background And Aims: In Africa, telemedicine holds great potential to revolutionize surgical care delivery, especially in areas where access to quality treatment is scarce. Data about the use of these services in African countries is, however, limited. To outline the present issues in surgical care delivery, as well as the significant role of telemedicine in advancing surgical care delivery in Africa.

Microglial Mayhem NLRP3 Inflammasome's Role in Multiple Sclerosis Pathology.

Introduction: This review delves into the intricate relationship between NLR inflammasomes, particularly the NLRP3 inflammasome, and the immune-mediated neurodegenerative disease, multiple sclerosis (MS). While the precise etiology of MS remains elusive, compelling research underscores the pivotal role of the immune response in disease progression. Notably, recent investigations highlight the significant involvement of NLRP3 inflammasomes in various autoimmune diseases, prompting an in-depth exploration of their impact on MS.

Correlations of Anthropometric Measurements With Body Fat Percentage, Fat Mass, and Fat Mass Index in School-Age Children.

Background: Childhood obesity is a growing public health issue globally, including in India. Anthropometric measures such as body mass index (BMI), waist circumference, and skinfold thickness are commonly used to estimate body fat percentage (BF%), but their correlations with fat mass (FM) and fat mass index (FMI) are less emphasized. This study aimed to explore the relationships between anthropometric measurements and body fat indicators (BF%, FM, and FMI) in school-age children and obtain prediction equations for FM and FMI.

Awareness and monitoring of infection control practices among healthcare workers in three primary health centers in India.

Objective: This study aimed to assess the awareness of and adherence to infection control practices among healthcare workers (HCWs) in three primary healthcare centers (PHCs) near Aurangabad City, Maharashtra, India.

Method: A prospective observational study over six months involved 64 HCWs from three PHCs (A, B, and C). Questionnaires and observation checklists based on guidelines from the WHO and the Systems for Improved Access to Pharmaceuticals and Services (SIAPS) were used to evaluate infection control practices across nine modules.

Colours of India: Uniting Endocrinologists in Fitness and Friendship.

Colours of India is an annual cultural phenomenon that transcends the boundaries of professional conferences, uniting endocrinologists through the universal language of music and dance. Since its inception in 2016, this vibrant event has brought together teams from across India and other participating countries, showcasing diverse dance forms while fostering friendships, promoting wellness, and celebrating cultural diversity within the medical community.

Assessing the Utilization of Large Language Model Chatbots for Educational Purposes by Medical Teachers: A Nationwide Survey From India.

Background Large language models (LLMs) are increasingly explored in healthcare and education. In medical education, they hold the potential to enhance learning by supporting personalized teaching, resource development, and student engagement. However, LLM use also raises concerns about ethics, accuracy, and reliance.

Trichosporon infection in chronic kidney disease patients from a tertiary care hospital - a case series or an outbreak? An unanswered question but a well-managed problem.

While the majority of spp. isolated in clinical laboratories are typically associated with episodes of colonization or superficial infections, this fungal species has gained recognition as an opportunistic pathogen, leading to invasive infections worldwide. In this article, we present a case series of spp.

Evaluation of the association between periodontal disease and total cancer risk: A cross-sectional study.

Background: The body is in a continuous state of inflammatory burden due to local and systemic inflammation, which is triggered in periodontal tissues in response to microorganisms. A number of studies have linked periodontitis to systemic diseases such as diabetes mellitus, cardiovascular disease and respiratory disease. Periodontal inflammation acts as a focus of infection, which can cause detrimental effects on distant target organs.

Cardiac output-guided haemodynamic therapy for patients undergoing major gastrointestinal surgery: OPTIMISE II randomised clinical trial.

Objectives: To evaluate the clinical effectiveness and safety of a perioperative algorithm for cardiac output-guided haemodynamic therapy in patients undergoing major gastrointestinal surgery.

Design: Multicentre randomised controlled trial.

Setting: Surgical services of 55 hospitals worldwide.

Effects of Revascularization on Cardiac Autonomic Neuropathy in Type 2 Diabetes Mellitus Patients With Chronic Stable Angina.

Background: Type 2 diabetes mellitus (T2DM) leads to cardiac autonomic neuropathy (CAN), affecting blood flow and heart rate regulation eventually causing chronic stable angina (CSA). Percutaneous coronary intervention (PCI) can correct autonomic dysfunctions and improve myocardial perfusion. This study aimed to assess CAN using heart rate variability (HRV) and cardiovascular reflex tests in T2DM patients with CSA before and after PCI.

Severity prediction markers in dengue: a prospective cohort study using machine learning approach.

Background: Dengue virus causes illnesses with or without warning indicators for severe complications. There are no clear prognostic signs linked to the disease outcomes.

Methods: Clinical and laboratory parameters among 102 adult including 17 severe dengue (SD), 33 with warning and 52 without warning signs during early and critical phases were analysed by statistical and machine learning (ML) models.

Effect of genetically predicted sclerostin on cardiovascular biomarkers, risk factors, and disease outcomes.

Sclerostin inhibitors protect against osteoporotic fractures, but their cardiovascular safety remains unclear. We conducted a cis-Mendelian randomisation analysis to estimate the causal effect of sclerostin levels on cardiovascular risk factors. We meta-analysed three GWAS of sclerostin levels including 49,568 Europeans and selected 2 SNPs to be used as instruments.

Pathology Report Interpretation and Disease Diagnosis Using Fuzzy Logic Embedded in an Artificial Intelligence Framework: A New Paradigm for Digital Technologies.

Introduction Accurate diagnosis is essential for effective treatment in healthcare settings. Digital technologies have revolutionized medical diagnostics, particularly in pathology laboratory report analyses, by enhancing speed, quality, and precision. Diagnostic pathology has advanced significantly with digital imaging, AI algorithms, and computer-assisted techniques.

Ultrasound-guided pulsed radiofrequency ablation of stellate ganglion in upper-extremity phantom limb pain: a case series.

Background: Phantom limb pain (PLP) is the most common type of pain experienced by amputees and is chronic and complex, with manifestations including pain in a limb that no longer exists. To date, treatments that are pharmaceutical or surgical in nature are relatively ineffective at bringing much relief as the pathophysiology of PLP is somewhat obscure. Chronic pain syndromes such as PLP may benefit from sympathetic nervous system modulation through the stellate ganglion.