Embryonic stem cells overexpressing high molecular weight FGF2 isoform enhance recovery of pre-ganglionic spinal root lesion in combination with fibrin biopolymer mediated root repair.

Background: Spinal ventral root avulsion results in massive motoneuron degeneration with poor prognosis and high costs. In this study, we compared different isoforms of basic fibroblast growth factor 2 (FGF2), overexpressed in stably transfected Human embryonic stem cells (hESCs), following motor root avulsion and repair with a heterologous fibrin biopolymer (HFB).

Methods: In the present work, hESCs bioengineered to overexpress 18, 23, and 31 kD isoforms of FGF2, were used in combination with reimplantation of the avulsed roots using HFB.

ANALYSIS OF PHOTOMETRIC FULL-FACE PARAMETERS WITH A DISTAL BITE TAKING INTO ACCOUNT THE TYPES OF MANDIBULAR GROWTH.

Objective: The aim: Determination of the peculiarities of full-face aesthetics in patients aged 10-13 years with a distal bite with different types of mandibular growth.

Patients And Methods: Materials and methods: 74 patients aged 10-13 years with a distal bite and various types of mandibular growth took part in the study. The methods of photostatic image study described by I.

MANAGEMENT OF COMPLICATIONS FOLLOWING BUTTON BATTERY INGESTION.

Ingestion of button batteries by children is increasing every year, which is becoming a clinical problem for pediatricians. The number of complications and mortality when using batteries exceeds similar indicators when accidentally swallowing other foreign bodies. This is due to the electrochemical and mechanical effect of the battery on the mucous membrane of the gastrointestinal tract and especially the esophagus.

INFECTIONS ASSOCIATED WITH OBSTETRIC AND GYNECOLOGICAL SURGERIES AS A CAUSE OF FEMALE INFERTILITY IN UKRAINE.

Objective: The aim: To assess the role of surgical site infections types associated with obstetric and gynecological surgeries as a cause of infertility among women reproductive age in Ukraine.

Patients And Methods: Materials and methods: We conducted a retrospective multicentre cohort study was based on reproductive health surveillance data among women reproductive age from 2019 to 2021. Definitions of infertility were used from the WHO and surgical site infections were used CDC/ NHSN.

SURGICAL SITE INFECTION AFTER LAPAROSCOPIC HYSTERECTOMY FOR BENIGN GYNECOLOGICAL DISEASE IN UKRAINE.

Objective: The aim: To obtain the first estimates of the current incidence, and risk factors for Surgical Site Infection (SSI) after laparoscopic hysterectomy, and antimicrobial resistance of responsible pathogens in Ukraine.

Patients And Methods: Materials and methods: We performed a multicenter prospective cohort study was patient-based on surveillance data for SSIs were according to CDC/NHSN methodology. This study included women's undergoing a laparoscopic hysterectomy in 8 hospitals from different regions of Ukraine from January 2018 to December 2020.

IMPACT OF MALOCCLUSION OF CLASS ІІ1 ACCORDING TO ANGLE'S CLASSIFICATION METHOD ON FACIAL ESTHETICS.

Objective: The aim: There is no information on the esthetic features of the face, which are typical of the patients with late mixed occlusion with maxillodental anomalies of Angle's class II1 depending on the types of mandible growth in domestic and foreign literature. To study the esthetic peculiarities in the face profile, which are typical of the patients aged 10-13 with maxillodental anomalies of Angle's class II1 with different types of mandible growth.

Patients And Methods: Materials and methods: 55 patients aged 10-13 with maxillodental anomalies of Angle's class II1 were examined.

DIAGNOSTIC FEATURES OF DYSFUNCTION IN CYTOKINE AND SYMPATHOADRENAL SYSTEMS WITH ISCHEMIC STROKE.

Objective: The aim: Was a comprehensive study of the changes in features like structural and functional parameters of brain tissue, cytokine profile and β-adrenoceptor in the acute period of ischemic stroke (IS) to optimise diagnosis and treatment. The study was conducted at the Department of Neurosurgery and Neurology at the Medical Institute of Sumy State University.

Patients And Methods: Materials and methods: Measurements of complex dielectric constant (CDC) were performed by EHF dielectrometry.

Spinal Reflex Recovery after Dorsal Rhizotomy and Repair with Platelet-Rich Plasma (PRP) Gel Combined with Bioengineered Human Embryonic Stem Cells (hESCs).

Dorsal root rhizotomy (DRZ) is currently considered an untreatable injury, resulting in the loss of sensitive function and usually leading to neuropathic pain. In this context, we recently proposed a new surgical approach to treat DRZ that uses platelet-rich plasma (PRP) gel to restore the spinal reflex. Success was correlated with the reentry of primary afferents into the spinal cord.

Noninvasive ventilation (advanced): course report.

http://ow.ly/RiTH30odWuX.

Positive health behaviours Polish and Ukrainian medical students in the context of chronic diseases.

Introduction: Medical studies and practicing the medical professions involve considerable psychological distress. Health risks associated with distress may be greater in people with health problems, especially in the case of insufficient self-care for health.

Aim: Investigating the frequency of positive health behaviours and avoiding risky behaviours among students of medical faculties with and without chronic diseases.

Structural and crystal-chemical characteristics of the apatite deposits from human aortic walls.

Thermal behavior of biological apatite is the object of several studies. Crystal size, carbonate content, phase composition, and other parameters change during annealing up to 900 °C in biological minerals with apatite structure. The way these parameters change reflects the specific properties of the initial bioapatite.

Combination of heterologous fibrin sealant and bioengineered human embryonic stem cells to improve regeneration following autogenous sciatic nerve grafting repair.

Background: Peripheral nerve injury is a worldwide clinical problem, and the preferred surgical method for treating it is the end-to-end neurorrhaphy. When it is not possible due to a large nerve gap, autologous nerve grafting is used. However, these surgical techniques result in nerve regeneration at highly variable degrees.

CHARACTERISTICS OF CHANGES IN COGNITIVE FUNCTIONS OF THE PATIENTS WITH HYPERTENSIVE DISEASE.

Decline of the cognitive functions is one of the modern medicine actual problem. The influence of hypertension as modifiable risk factor in the evolution of cognitive impairment is emphasized in numerous investigations. Almost all the proposed in research literature data were obtained from the investigation of old patients group, who had high indexes of blood pressure and stroke histories.

Pathogenesis of Warthin's tumors.

Introduction: Warthin's tumor, also known as papillary cystadenoma lymphomatosum, monomorphic adenoma, or adenolymphoma, is a benign cystic tumor of the salivary glands containing abundant lymphocytes and lymph node-like stroma. It is named after the pathologist Aldred Scott Warthin, who described two cases in 1929.

Objective: The aim of this study is to analyze the pathogenesis of Warthin's tumor.

Optical coherence tomography diagnostics for onco-urology. Review of clinical perspectives.

Introduction: Optical coherence tomography (OCT) is being investigated widely for use in urologic pathology. The current imaging of urogenital cancers cannot be perfect, thus, routine methods demands new updates or inventions of alternative radiological scope. OCT presents so-called "live" optical biopsy.

[Correlation between long-term proton pump ingibitor use, homocysteine and lipoproteins serum concentrations in patients with comorbidity of ischemic heart disease and acid peptic disease].

Present article is devoted to the study of the correlation between vitamin B12 serum level, hyperhomocysteinaemia and dyslipidemia. During research there were discovered that the lowest vitamin B12 serum level and the highest homocysteine serum level have been registrated in associated pathology (ischemic heart disease and acid peptic disease according to long-term proton pump inhibitor use) patients. It was shown evident correlation between that changes and dyslipidemia.