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Impact of heterozygote CFTR mutations in COPD patients with chronic bronchitis.

Respir Res

February 2014

Department of Medicine, University of Alabama at Birmingham, MCLM 706 1918 University Blvd,, Birmingham, AL, USA.

Background: Cigarette smoking causes Chronic Obstructive Pulmonary Disease (COPD), the 3rd leading cause of death in the U.S. CFTR ion transport dysfunction has been implicated in COPD pathogenesis, and is associated with chronic bronchitis.

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